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Systemischer Lupus erythematodes und seltene rheumatische Erkrankungen (Mixed connective tissue disease, Sjögren-Syndrom, eosinophile Fasziitis)

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Pädiatrie

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Definition. Der systemische Lupus erythemathodes (SLE) ist eine B-Zell-vermittelte, chronisch-entzündliche Autoimmunkrankheit, die gekennzeichnet ist durch Produktion von Autoantikörpern gegen Zellkernbestandteile und Ablagerung von Immunkomplexen, die eine Vaskulitis verursachen. Zahlreiche Organe wie z. B. Haut, Niere, Lunge und ZNS können betroffen sein. Die Erstbeschreibung des SLE als Systemerkrankung erfolgte durch Kaposi 1872 (Abb. 87.1 , 87.2).

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Author information

Authors and Affiliations

  1. Klinik für Kinder- und Jugendmedizin der RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany

    Prof. Dr. med. N. Wagner

  2. Pädiatrisches Zentrum, Pädiatrie 1, Olgahospital, Bismarckstr. 8, 70031, Stuttgart, Germany

    Prof. Dr. G. Dannecker

Authors
  1. Prof. Dr. med. N. Wagner
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  2. Prof. Dr. G. Dannecker
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Editor information

Editors and Affiliations

  1. Universitäts-Kinderklinik, Adenauerallee 119, 53113, Bonn, Germany

    Michael J. Lentze

  2. Universitäts-Kinderklinik, Martinistr. 52, 20246, Hamburg, Germany

    Franz J. Schulte

  3. Universitäts-Kinderklinik, Schwanenweg 20, 24105, Kiel, Germany

    Jürgen Schaub

  4. Universitäts-Kinderklinik, Langenbeckstr. 1, 55101, Mainz, Germany

    Jürgen Spranger

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© 2007 Springer Medizin Verlag Heidelberg

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Wagner, N., Dannecker, G. (2007). Systemischer Lupus erythematodes und seltene rheumatische Erkrankungen (Mixed connective tissue disease, Sjögren-Syndrom, eosinophile Fasziitis). In: Lentze, M.J., Schulte, F.J., Schaub, J., Spranger, J. (eds) Pädiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76460-1_88

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  • DOI: https://doi.org/10.1007/978-3-540-76460-1_88

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-71895-6

  • Online ISBN: 978-3-540-76460-1

  • eBook Packages: Medicine (German Language)

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