Abstract
Symbolic dynamics was used to investigate the effect of breath-holding on brain functional Magnetic Resonance Imaging (fMRI). Data from an open Internet database were used. Two conditions were compared: breath-holding (on-off task period of 30 seconds) and resting. A symbolic dynamics parameter P(n), equal to the proportion of brain voxels with positive derivatives at each scan in a run, was calculated from the blood oxygenation level dependent (BOLD) signal. The robustness of P(n) was assessed by comparing the results of the original data and data split into odd and even slices. Slice-time correction was also investigated. The average normalized spectrum of P(n) of all breath-holding runs had greater power peaks at the breath-holding frequency (fbh=1/30 Hz), contributing with about 35% of the total signal power, whereas none of the resting runs showed similar behavior. In all cases, P(n) indicated global, periodic effects caused by the respiratory modulation in all breath-holding runs, as opposed to the resting runs.
Keywords
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Referências
Ogawa S, Lee TM et al. (1990). Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci 87:9868–9872
Raj D, Paley DP et al. (2000). A model for susceptibility artifacts from respiration in functional echo-planar magnetic resonance imaging. Physics in Med and Biol 45:3809–3820
Posse S, Olthoff U, Weckesser M et al. (1997) Regional Dynamic Signal Changes during Controlled Hyperventilation Assessed with Blood Oxygen Level-Dependent Functional MR Imaging. Amer Jn Neuroradiology 18:1763–1770.
Hoge RD, Atkinson J, Gill B et al. (1999). Investigation of BOLD Signal Dependence on Cerebral Blood Flow and Oxygen Consumption: The Deoxyhemoglobin Dilution Model. Magn Res in Med; 42:849–863
Windischberger C, Langenberger H, Sycha T et al. (2002) On the origin of respiratory artifacts in BOLD-EPI of the human brain. Magn Res Imaging; 20:575–582.
Stillman AE, Hu X, Jerosch-Herold M. (1995) Functional MRI of brain during breath holding at 4 T. Magn Res Imaging; 13(6): 893–897.
Kastrup A., Li TQ, Glover GH et al. (1999) Cerebral blood flowrelated signal changes during breath holding. Amer Jn of Neuroradiology; 20(7): 1233–1238.
Weckesser M, Posse S, Olthoff U et al. (1999) Functional Imaging of the Visual Cortex with Bold-Contrast MRI: Hyperventilation Decreases Signal Response. Magn Res in Med; 41:213–216.
Abbott DF, Opdam HI, Briellmann RS et al. (2005) Brief Breath Holding May Confound Functional Magnetic Resonance Imaging Studies. Hum Brain Map; 24:284–290
Kastrup, A., Kruger, G., Glover et al. (1999). Assessment of cerebral oxidative metabolism with breath holding and fMRI. Magn. Reson. Med. 42(3), 608–611.
K.C. Andrade, O.M. Pontes-Neto, J.P. Leite et al. (2006) Quantitative Aspects of Brain Perfusion Dynamic Induced by BOLD fMRI. Arq. Psiquiatria 64(4):895–898
Jensen EW, Guillen P, Limn H et al. (2000) Symbolic Dynamics Applied to EEG Signal for Monitoring Anaesthetic Depth During Propofol Infusion. In: Proc 22nd Annual EMBS Confe. Chicago, 2000.
Projeto First BIRN. Dados de “Phase I”, (accession number undefined). Site: http://www.nbirn.net
Macey PM, Macey KE et al. (2004) A method for removal of global effects from fMRI time series. Neuroimage 22:360–366.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Elefteriadis, C., Jandre, F.C., Infantosi, A.F.C. (2007). Dinâmica Simbólica Aplicada à Análise do Efeito da Apneuse em Imagens de Ressonância Magnética Funcional Cerebral. In: Müller-Karger, C., Wong, S., La Cruz, A. (eds) IV Latin American Congress on Biomedical Engineering 2007, Bioengineering Solutions for Latin America Health. IFMBE Proceedings, vol 18. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74471-9_73
Download citation
DOI: https://doi.org/10.1007/978-3-540-74471-9_73
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-74470-2
Online ISBN: 978-3-540-74471-9
eBook Packages: EngineeringEngineering (R0)