Auszug
Nozizeption ist bereits ab der 20.–22. Schwangerschaftswoche (SSW) möglich. Kortikale Schmerzverarbeitung geschieht ab der 24. Schwangerschaftswoche (Wolf 1999; ▸ Kap. 1 u. 2) Dabei ist bei Früh- und Neugeborenen das zentrale Schmerzhemmungssystem deutlich schlechter ausgebildet als das nozizeptive System, sodass beim Früh- und Neugeborenen generell vom Überwiegen nozizeptiven Stresses auszugehen ist (▸ Kap. 2).
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Hünseler, C., Roth, B., Michel, E., Dubbel, G., Zernikow, B. (2009). Klinisch-pharmakologische Grundlagen der Schmerztherapie. In: Zernikow, B. (eds) Schmerztherapie bei Kindern, Jugendlichen und jungen Erwachsenen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74065-0_6
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