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Bis zum Schulalter fehlt es dem Kind an Einsicht, sich mit seiner Krankheit und den notwendigen Diagnostik- und Therapiemaßnahmen soweit auseinanderzusetzen, dass es diese akzeptiert. Das Erdulden schmerzhafter Prozeduren bedeutet für das Kind Stress, eine adäquate Angst- und Schmerztherapie somit Stressreduktion. Erhöhte Morbidität und Mortalität durch unzureichende Stressprävention gerade auch bei sehr jungen Patienten sind u. a. von (1987), die negativen Langzeiteffekte auf die psychische Entwicklung u.a. von der Arbeitsgruppe um (1998) eindrucksvoll beschrieben worden. Häufige, repetitive Schmerzstimuli leiten Chronifizierungsprozesse ein.

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Literatur

  • Abu-Shahwan I, Mack D (2007) Propofol and Remifentanil for deep sedation in children undergoing gastrointestinal endoscopy. Paediatr Anaesth 17: 460–463

    Article  PubMed  Google Scholar 

  • Adams HA, Werner C (1997) Vom Razemat zum Eutomer: SKetamine, Renaissance einer Substanz? Anaesthesist 46: 1026–1042

    Article  PubMed  CAS  Google Scholar 

  • Aldrete JA (1995) The postoperative recovery score revisited. J Clin Anesth 7: 89–91

    Article  PubMed  CAS  Google Scholar 

  • American Academy of Pediatrics Committee on Drugs (1992) Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures. Pediatrics 89: 1110–1115

    Google Scholar 

  • American Academy of Pediatrics, Committee on Psychosocial Aspects of Child and Family Health (2001) The assessment and management of acute pain in infants, children, adolescents. Pediatrics 108: 793–797

    Article  Google Scholar 

  • American Academy of Pediatrics/American Academy of Pediatric Dentistry. Coté CJ, Wilson S. Workgroup on Sedation (2006) Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics 118; 2587–2602

    Article  Google Scholar 

  • American Society of Anesthesiologists (2002) Practical guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology 96: 1004–1017 (2002)

    Article  Google Scholar 

  • Anand KJ, Sippell WG, Aynsley-Green A (1987) Randomised trial of fentanyl anaesthesia in preterm babies undergoing surgery: effects on the stress response. Lancet I: 243–247

    Article  Google Scholar 

  • Anand KJS (1998) Clinical importance of pain and stress in preterm neonates. Biol Neonate 73: 1–9

    Article  PubMed  CAS  Google Scholar 

  • Anderson JL, Junkins E, Pribble C, Guenther E (2007) Capnography and depth of sedation during propofol sedation in children. Ann Emerg Med 49: 9–13

    Article  PubMed  Google Scholar 

  • Annequin D, Carbajal R, Chauvin P, Gall O, Tourniaire B, Murat I (2000) Fixed 50% Nitrous Oxide Oxygen Mixture for Painful Procedures: A French Survey. Pediatrics 105: 47–53

    Article  Google Scholar 

  • Antmen B, Sasmaz I, Birbicer H, Ozbek H, Burgut R, Isik G, Kilinic Y (2005) Safe and effective sedation and analgesic for bone marrow aspiration procdures in children with alfentanil, remifentanil and combination with midazolam. Pediatr. Anaesth 15: 214–219

    Article  Google Scholar 

  • Axelin A, Salanterä S, Lektonen L (2006) „Facilitated tucking by parents“ in pain management of preterm infants — a randomized crossover trial. Early Hum Dev 82: 341–241

    Article  Google Scholar 

  • Barbi E, Petaros P, Badiona L, Pahor T, Guiseppin I, Biasotto E, Martelossi S, DiLeo G, Sarti A, Ventura A (2006) Deep sedation with propofol for upper gastrointestinal endoscopy in children, administered by specially trained pediatricians: a prospective case series with emphasis on side effects. Endoscopy 38: 368–375

    Article  PubMed  CAS  Google Scholar 

  • Berkenbosch JW, Graff GR, Stark JM, Ner Z, Tobias JD (2004) Use of a remifentanil-propofol mixture for pediatric fiberoptic bronchoscopy sedation. Paediatr Anaesth 14: 941–946

    Article  PubMed  Google Scholar 

  • Berry FA (1998) Preemptive analgesia for postoperative pain. Paed Anaesth 8: 187–188

    Article  CAS  Google Scholar 

  • Bucher HU, Moser T, vonSiebenthal K, Kiel M, Wolf M, Duc G (1995) Sucrose reduces pain reaction to heel lancing in preterm infants. Pediatr Res 83: 332–335

    Google Scholar 

  • Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (2008) Technische Regel für Gefahrstoffe, 525. www baua.de

    Google Scholar 

  • Cignacco E, Hamers JP, Stoffel L, vanLingen RA, Gessler P, McDongall J, Nelle M (2007) The efficacy of non-pharmacological interventions in the management of procedural pain in preterm and term neonates. A systematic literature review. E J Pain, 11: 139–152

    Article  Google Scholar 

  • Cote CJ (1994) Sedation for the pediatric patient — a review. Pediatr North Am 41: 31–58

    CAS  Google Scholar 

  • Cravero JP, Blike GT, Beach M, Gallagher SB, Hertzog JH, Havidich JE, Gelman B and the Pediatric Sedation Research Consortium (2006) Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the pediatric sedation research consortium. Pediatrics 118: 1087–1096

    Article  PubMed  Google Scholar 

  • Dalal PG PG, Murray D, Cox T, McAllister J, Snider R (2006) Sedation and anesthesia protocols used for magnetic resonance imaging studiesin Infants: provider and pharmacological considerations. Anesth Analg 103: 863–868

    Article  PubMed  CAS  Google Scholar 

  • Duce D, Glaisyer H, Sury M (2000) An evaluation of propofol combined with remifentanil: a new intravenous anaesthetic technique for short painful procedures in children. Paed Anaesth 10: 689–690

    Google Scholar 

  • Duncan HP, Zurick NJ, Wolf AR (2001) Should we consider awake neonatal intubation? A review of the evidence and treatment strategies. Paed Anaesth 11: 135–145

    Article  CAS  Google Scholar 

  • Ekbom K, Jakobsson J, Marcus C (2005) Nitrous oxide inhalation is a safe and effective way to facilitate procedures in paediatric outpatient departments. Arch Dis Child 90: 1073–1076

    Article  PubMed  CAS  Google Scholar 

  • Fodale V, La Monaca E (2008) Propofol infusion Syndrome: an overview of a perplexing disease. Drug Saf 31: 293–303

    Article  PubMed  CAS  Google Scholar 

  • Gilchrist F, Whitters CJ, Cairns AM, Simpson M, Hosey MT (2007) Exposure to nitrous oxide in a paediatric dental unit. Int J Paediatr Dent 17: 116–122

    Article  PubMed  Google Scholar 

  • Gottschling S, Meyer S, Reinhard H, Furtwängler R, Klotz D, Graf N (2006) Intraindividual propofol dosage variability in children undergoing repetitive procedural sedations. Pediatr Hematol Oncol 23: 571–578

    Article  PubMed  CAS  Google Scholar 

  • Gourrier E, Karroubi P, el Hanache A, Merbouche S, Mouchino G, Lerailles J (1996) Use of EMLA®-cream in a department of neonatology. Pain 68: 431–343

    Article  PubMed  CAS  Google Scholar 

  • Greenberg SB, Faerber EN, Aspinall CL, Adams RC (1993) Highdose chloralhydrate sedation for children undergoing MR imaging. AJR 161: 639–641

    PubMed  CAS  Google Scholar 

  • Grunau RE (1998) Longterm effects of pain. Res Clin Forum 20/4: 19–28

    Google Scholar 

  • Halperin SA, Smith B, Houston T (2000) Lidocaine-prilocaine patch decreases the pain associated with the subcutaneous administration of measles-mumps-rubella vaccine but does not adversely affect the antibody response. J Ped 136: 189–194

    Article  Google Scholar 

  • Helbo-Hansen S, Westergaard V, Krogh BL, Svendson HP (1988) The reduction of pain on injection of propofol: The effect of addition of lignocaine. Acta Anaesth Scand 32: 502–504

    Article  PubMed  CAS  Google Scholar 

  • Höhne C, Reinhold P (2008) Stellungnahme zur Verwendung von Lachgas zur Sedierung von Kindern bei zahnärztlichen Eingriffen. Anästhesiologie und Intensivmedizin 10: 534–535

    Google Scholar 

  • Holroyd I (2008) Conscious sedation in pediatric dentistry. A short review of the current guidelines and the technique of inhalational sedation with nitrous oxide. Paediatr Anaesth 18: 13–17

    PubMed  CAS  Google Scholar 

  • Jamieson J (1999) Anesthesia and sedation in the endoscopy suite? (influences and options). Curr Opin Anaesthesiol 12: 417–423

    Article  PubMed  CAS  Google Scholar 

  • Jayabose S, Levendoglu-Tugal O, Giamelli J, Grodin W, Cohn M, Sandoval C, Ozkaynak F, Kubal K, Nosetti M, Uman J, Visintainer P (2001) Intravenous anesthesia with propofol for painfull procedures in children with cancer. J Pediatr Hematol Oncol 23: 290–293

    Article  PubMed  CAS  Google Scholar 

  • Kanagasundaram SA, Lane LJ, Cavaletto BP, Keneally JP, Cooper MG (2001) Efficacy and safety of nitrous oxide in alleviating pain and anxiety during painful procedures. Arch Dis Child 84: 492–495

    Article  PubMed  CAS  Google Scholar 

  • Karl HW, Keifer AT, Rosenberger JL, Larach MG, Ruffle JM (1992) Comparison of safety and efficacy of intranasal midazolam orsufentanilfor preinduction of anesthesia in pediatric patients. Anesthesiology 76: 209–215

    Article  PubMed  CAS  Google Scholar 

  • Keidan I, Gozal D, Minuskin T, Weinberg M, Barkaly H, Augarten A (2004) The effect of fasting practise on sedation with chloral hydrate. Pediatr Emerg Care 20: 805–807

    Article  PubMed  Google Scholar 

  • Keidan I, Berkenstadt H, Sidi A, Perel A (2001) Propofol/remifentanil vs. propofol alone for bone marrow aspiration in paediatric haematooncological patients. Paed Anaesth 11: 297–301

    Article  CAS  Google Scholar 

  • Koscielniak-Nielsen Z, Hesselbjerg L, Brushoj J, Jensen MB, Pedersen HS (1998) EMLA®-patch for spinal puncture. Anaesthesia 53: 1209–1227

    Article  Google Scholar 

  • Kraus GB, Gruber RG, Knoll R, Danner U (1989) Pharmakokinetische Untersuchungen nach intravenöser und rektaler Applikation von Midazolam bei Kindern. Anaesthesist 38: 658–663

    PubMed  CAS  Google Scholar 

  • Kuiper M de (1999) Schmerz und Schmerzmanagement bei Kindern. Ullstein Medical, Wiesbaden

    Google Scholar 

  • Lamireau T, Dubbreuil M, Daconceicao, M (1998) Oxygen saturation during esophagogastroduodeno-scopy in children: general anesthesia vs. intravenous sedation. J Ped Gastroenterol Nutr 8: 491–499

    Google Scholar 

  • Larsson BA, Jylli L, Langercrantz H, Olsson GL (1995) Does a local anaesthetic cream (EMLA®) alleviate pain from heel-lancing in neonates? Acta Anaesthesiol Scand 23: 1028–1031

    Article  Google Scholar 

  • Larsson BA, Tannfeldt G, Langercrantz H, Olsson GL (1998) Alleviation of the pain of venepuncture in neonates. Acta Paediatr 87: 774–779

    Article  PubMed  CAS  Google Scholar 

  • Lefever EB, Poter PS, Seeley NR (1993) Propofol sedation for pediatric MRI (letter) Anesth Analg 76: 919–920

    Article  PubMed  CAS  Google Scholar 

  • Lehn BM (1993) Psychologische Methoden der Schmerzbehandlung bei Kindern. In: Meier H, Kaiser R, Moir CR (Hrsg) Schmerz beim Kind. Springer, Berlin Heidelberg New York Tokio

    Google Scholar 

  • Litman RS, Bakowitz RJ, Ward DS (1996) Levels of conciousness and ventilatory parameters in young children during sedation with oral midazolam and nitrous oxide. Arch Pediatr Adolesc Med 150: 671–675

    PubMed  CAS  Google Scholar 

  • Lerman J, Strong HA, Ledez KM (1989) Effects of age on the serum concentration of AAE and the binding of lidocaine in pediatric patients. Clin Pharmacol Ther 46: 219–225

    PubMed  CAS  Google Scholar 

  • Lesmes CE, Hager H, Nussenson E, Katz Y (1998) Sedation of paediatric endoscopic procedures: comparison of two techniques. Br J Anaesth 80 (Suppl): 142–14344.

    Google Scholar 

  • Machata AM, Willschke H, Kabon B, Kettner SC, Marhofer P (2008) Propofol-based sedation regime for infants and children undergoing ambulatory magnetic resonance imaging. Br J Anaesth 101: 239–243

    Article  PubMed  CAS  Google Scholar 

  • Malinovsky JM, Lejus C, Servin F, Leplage F, Le Normand Y, Testa S, Cozian A, Pinaud M (1993) Plasmaconcentrations of midazolam after i. v., nasal or rectal administration in children. Br J Anaesth 70: 617–620

    Article  PubMed  CAS  Google Scholar 

  • Malviya S, Voelpel-Lewis T, Tait AR (1997) Adverse events and risk factors associated with the sedation of children by nonanesthesiologists. Anesth Analg 85: 1207–1213

    Article  PubMed  CAS  Google Scholar 

  • Mart CR, Parrish M, Rosen KL, Dettorre MD, Ceneviva GD, Lucking SE, Thomas NJ (2006) Safety and efficacy of sedation with propofol for transoesophageal echocardiography in children in an outpatient setting. Cardiol Young 16: 152–156

    Article  PubMed  Google Scholar 

  • Marx CM, Stein J, Tylor MK Nieder ML, Shurin SB, Blumer JL (1997) Ketamine-midazolam vs meperidine-midazolam for painful procedures on pediatric oncology patients. J Clin Oncol 15: 94–102

    PubMed  CAS  Google Scholar 

  • McCarty EC, Mencio GA, Walker LA, Green NE (2000) Ketamine sedation for the reduction of children’s fractures in the emergency department. J Bone Joint Surg Am 82: 912–918

    PubMed  Google Scholar 

  • McDowall RH, Scher CS, Barst SM (1995) Total intravenous anesthesia for children undergoing brief diagnostic or therapeutic procedures. J Clin Anesth 7: 273–280

    Article  PubMed  CAS  Google Scholar 

  • McIntosh N, vanVeen L, Brameyer H (1994) Alleviation of the pain of heel prick in preterm infants. Arch Dis Child 7177–181

    Google Scholar 

  • Melloni C (2007) Anesthesia and sedation outside the operating room: how to prevent risk and maintain good quality. Curr Opin Anaesthesiol 20: 513–519

    PubMed  Google Scholar 

  • Meyer S, Shamdeen MG, Kegel B, Mencke T, Gottschling S, Gortner L, Grundmann U (2006) Effect of propofol on seizure-like phenomena and electroencephalograpgic activity in children with epilepsy vs children with learning difficulties. Anaesthesia 61: 1040–1047

    Article  PubMed  CAS  Google Scholar 

  • Meyer S, Aliani S Graf N, Gottschling (2004) Inter-and intraindividual variability in ketamine dosage in repetitive procedures in children with malignancies. Pediatr Hematol Oncol 21: 161–166

    Article  PubMed  CAS  Google Scholar 

  • Mitchell RK, Koury S, Stone CK (1996) Respiratory arrest after intramuscular ketamine in a 2-year-old child. Am J Emerg Med 14: 580–581

    Article  PubMed  CAS  Google Scholar 

  • Molter G, Castor G, Altmayer P, Büch U (1990) Psychosomatische, sedative und hämodynamische Reaktionen nach präoperativer oraler Gabe von Midazolam bei Kindern. Kl in Pädiatr 202: 328–333

    Article  CAS  Google Scholar 

  • Morton NS (1998) Total intravenous anaesthesia (TIVA) in pediatrics: advantages and disadvantages. Paed Anaesth 8: 189–194

    Article  CAS  Google Scholar 

  • Muray DJ, Mehta MP, Forps RB, Dull DL. (1990) Additive contribution of nitrous oxide to halothane MAC in infants and children. Anesth Analg 71: 120–124

    Article  Google Scholar 

  • Niesel HC, Kaiser H (1991) Grenzdosis für Lokalanästhetika. Empfehlungen nach toxikologischen und pharmakokinetischen Daten. Regionalanästhesie 14: 79

    CAS  Google Scholar 

  • Parker RI, Mahan RA, Giugliano D, Parker MM (1997) Efficacy and safety of intravenous midazolam and ketamine as sedation for therapeutic and diagnostic procedures in children. Pediatrics 99: 427–431

    Article  PubMed  CAS  Google Scholar 

  • Raoof AA, van Obbergh LJ, Verbeck RK (1995) Propofol pharmacokinetics in children with biliary atresia. Br J Anaesth 74: 46–49

    Article  PubMed  CAS  Google Scholar 

  • Reeves ST, Havidich JE, Tobin DP (2004) Conscious sedation of children with propofol is anything but conscious. Pediatrics 114: 74–76

    Article  Google Scholar 

  • Reinhold P, Graichen B (1999) Propofol zur Sedierung bei pädiatrischen Kernspintomographie-Untersuchungen. Klin Pädiatr 211: 40–43

    Article  PubMed  CAS  Google Scholar 

  • Reinhold p Usselmann B (1999) Der nichtbestimmungsgemäße Gebrauch zugelassener Medikamente in der Anästhesie. Anästh Intensivmed 40: 701–708

    Google Scholar 

  • Rey E, Delauny L, Pons G, Murat I, Richard MO, Saint-Maurice C, Olive G (1991) Pharmacokinetics of midazolam in children: Comparative study of intranasal and intravenous administration. Eur J Clin Pharmacol 41: 355–357

    Article  PubMed  CAS  Google Scholar 

  • Richardson J, Smith JE, McCall G, Pilkington K (2006) Hypnosis for procedure-related pain and distress in pediatric cancer patients: a systematic review of effectiveness and methodology related to hypnosis interventions. J Pain Symptom Manage 31: 70–84

    Article  PubMed  Google Scholar 

  • Robbertze R, Posner KL, Domino KB (2006) Closed claims review of anesthesia for procedures outside the operating room. Curr Opin Anaesthesiol 19: 436–442

    Article  PubMed  Google Scholar 

  • Schmitt EL, Baum VC (2008) Nitrous oxide in pediatric anesthesia: friend or foe? Curr Opin Anaesthesiol 21: 356–359

    Article  PubMed  Google Scholar 

  • Sievers TD, Yee JD, Foley RN, Blanding PJ, Berde CB (1991) Midazolam for conscious sedation during pediatric oncology procedures: safety and recovery parameters. Pediatrics 88: 1172–1179

    PubMed  CAS  Google Scholar 

  • Singer AJ, Taira BR, Chisena EN, Gupta N, Chipley J (2008) Warm lidocaine/tetracaine patch versus placebo before pediatric intravenous cannulation: a randomized controlled trial. Ann Emerg Med 52: 41–47

    Article  PubMed  Google Scholar 

  • Stevens B, Yamada J, Ohlsson A (2001) Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev 4: CD 001069

    Google Scholar 

  • Taddio A, Shennan AT, Stevens B, Leeder JS (1995) Safety of lidocaine-prilocaine-cream in the treatment of preterm neonates. Pediatrics 127: 1002–1005

    Article  CAS  Google Scholar 

  • Taddio A, Ohlsson, A, Einarson TR, Stevens B, Koren G (1998) A systematic review of lidocaine-prilocaine-cream (EMLA®) in the treatment of acute pain in neonates. Pediatrics 101: E1

    Article  PubMed  CAS  Google Scholar 

  • Tashiro C, Matsui Y, Nakano S (1991) Respiratory outcome in extremely premature infants following ketamine anaesthesia. Can J Anaesth 38: 287–291

    Article  PubMed  CAS  Google Scholar 

  • Tobias JD, Phipps S, Smith B, Mulhern RK (1992) Oral ketamine premedication to alleviate the distress of invasive procedures in pediatric oncology patients. Pediatrics 90: 537–541

    PubMed  CAS  Google Scholar 

  • Tosun Z, Aksu R, Guler G, Esmaoglu A, Akin A, Aslan, Boyaci A (2007) Propofol-ketamine vs propofol-fentanyl for sedation during pediatric upper gastrointestinal endoscopy. Paediatr Anaesth 17: 983–988

    Article  PubMed  Google Scholar 

  • Vandermeersch E, van Hemelrijck J, Byttebier G, van Aken H (1989) Pharmacokinetics of propofol during continuous infusion for pediatric anesthesia. Acta Anaesth Belg 40: 161–165

    PubMed  CAS  Google Scholar 

  • Vangerven M, Van Hemelrijck J, Wouters P, Vandermeersch E, Van Aken H (1992) Light anaesthesia with propofol for pediatric MRI. Anaesthesia 47: 706–707

    Article  PubMed  CAS  Google Scholar 

  • Vasile B, Masulo F, Candiani A, Latronico N (2003) The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med 29: 1417–1425

    Article  PubMed  Google Scholar 

  • Von Heijne M, Bredlöv B, Söderhäll S, Ollson GL (2004) Propofol or propofol-alfentanil anesthesia for painful procedures in the pediatric oncology ward. Ped. Anesth 14: 670-675 Zeltzer LK, Altman A, Cohen D et al. (1990) Report of the subcommitee on the management of pain associated procedures in children with cancer. Pediatrics 86: 826–831

    Google Scholar 

  • Zernikow B, Meyerhoff U, Michel E, Wiesel T, Hasan C, Janssen G, Kuhn N, Kontny U, Fengler R, Görtitz I, Andler W (2005) Pain in pediatric oncology-children’s and parent’s perspectives. Eur J Pain 9: 495–406

    Article  Google Scholar 

  • Ziegler JW, Todres ID (1992) Intubation in newborns. Am J Dis Child 146: 147–149

    PubMed  CAS  Google Scholar 

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Reinhold, P., Köster-Oehlmann, P. (2009). Schmerzhafte interventionelle Eingriffe. In: Zernikow, B. (eds) Schmerztherapie bei Kindern, Jugendlichen und jungen Erwachsenen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74065-0_13

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