Skip to main content
SpringerLink
Log in

Neurophysiologic Mapping for Glioma Surgery: Preservation of Functional Areas

  • Reference work entry
Textbook of Stereotactic and Functional Neurosurgery

Abstract

The resection of tumors located within or adjacent to eloquent cortical regions is often necessary to alleviate focal neurological deficits secondary to mass effect and increased intracranial pressure. In addition, there is growing evidence that greater extent of tumor resection correlates with increased time to tumor progression and overall survival for glioma patients [1,2–4]. The surgical aim is to achieve maximal tumor removal without producing permanent morbidity. Neurophysiological mapping of functional areas is critical for minimizing the morbidity associated with removing abnormal tissue from eloquent cortex.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 899.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Berger MS, Deliganis AV, Dobbins J, Keles GE. The effect of extent of resection on recurrence in patients with low grade cerebral hemisphere gliomas. Cancer 1994;74:1784–91.

    Article  PubMed  CAS  Google Scholar 

  2. Keles GE, Anderson B, Berger MS. The effect of extent of resection on time to tumor progression and survival in patients with glioblastoma multiforme of the cerebral hemisphere. Surg Neurol 1999;52:371–9.

    Article  PubMed  CAS  Google Scholar 

  3. Keles GE, Lamborn KR, Berger MS. Low-grade hemispheric gliomas in adults: a critical review of extent of resection as a factor influencing outcome. J Neurosurg 2001;95:735–45.

    Article  PubMed  CAS  Google Scholar 

  4. Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi W, DeMonte F, Lang FF, McCutcheon IE, Hassenbusch SJ, Holland E, Hess K, Michael C, Miller D, Sawaya RA. multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 2001;95:190–8.

    Article  PubMed  CAS  Google Scholar 

  5. Penfield W, Boldrey E. Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 1937;60:389–443.

    Article  Google Scholar 

  6. Berger MS, Kincaid J, Ojemann GA, Lettich E. Brain mapping techniques to maximize resection, safety, and seizure control in children with brain tumors. Neurosurgery 1989;25:786–92.

    Article  PubMed  CAS  Google Scholar 

  7. Skirboll SS, Ojemann GA, Berger MS, Lettich E, Winn HR. Functional cortex and subcortical white matter located within gliomas. Neurosurgery 1996;38:678–84; discussion 675–84.

    Article  PubMed  CAS  Google Scholar 

  8. Benzel EC, Lewine JD, Bucholz RD, Orrison WW Jr. Magnetic source imaging: a review of the Magnes system of biomagnetic technologies incorporated. Neurosurgery 1993;33:252–9.

    Article  PubMed  CAS  Google Scholar 

  9. Gallen CC, Sobel DF, Waltz T, Aung M, Copeland B, Schwartz BJ, Hirschkoff EC, Bloom FE. Noninvasive presurgical neuromagnetic mapping of somatosensory cortex. Neurosurgery 1993;33:260–8; discussion 268.

    Article  PubMed  CAS  Google Scholar 

  10. Berman JI, Berger MS, Mukherjee P, Henry RG. Diffusion-tensor imaging-guided tracking of fibers of the pyramidal tract combined with intraoperative cortical stimulation mapping in patients with gliomas. J Neurosurg 2004;101:66–72.

    Article  PubMed  Google Scholar 

  11. Berman JI, Berger MS, Chung SW, Nagarajan SS, Henry RG. Accuracy of diffusion tensor magnetic resonance imaging tractography assessed using intraoperative subcortical stimulation mapping and magnetic source imaging. J Neurosurg 2007;107:488–94.

    Article  PubMed  Google Scholar 

  12. Ojemann GA. The neurobiology of language and verbal memory: observations from awake neurosurgery. Int J Psychophysiol 2003;48:141–6.

    Article  PubMed  Google Scholar 

  13. Ojemann G, Ojemann J, Lettich E, Berger M. Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients. J Neurosurg 1989;71:316–26.

    Article  PubMed  CAS  Google Scholar 

  14. Lucas TH II, McKhann GM II, Ojemann GA. Functional separation of languages in the bilingual brain: a comparison of electrical stimulation language mapping in 25 bilingual patients and 117 monolingual control patients. J Neurosurg 2004;101:449–57.

    Article  PubMed  Google Scholar 

  15. Roux FE, Tremoulet M. Organization of language areas in bilingual patients: a cortical stimulation study. J Neurosurg 2002;97:857–64.

    Article  PubMed  Google Scholar 

  16. Walker JA, Quinones-Hinojosa A, Berger MS: Intraoperative speech mapping in 17 bilingual patients undergoing resection of a mass lesion. Neurosurgery 2004;54:113–17; discussion 118.

    Article  PubMed  Google Scholar 

  17. Bello L, Acerbi F, Giussani C, Baratta P, Taccone P, Songa V, Fava M, Stocchetti N, Papagno C, Gaini SM. Intraoperative language localization in multilingual patients with gliomas. Neurosurgery 2006;59:115–25; discussion 115-25.

    Article  PubMed  Google Scholar 

  18. Roux FE, Boulanouar K, Lotterie JA, Mejdoubi M, LeSage JP, Berry I. Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation. Neurosurgery 2003;52:1335–45; discussion 1337–45.

    Article  PubMed  Google Scholar 

  19. Duffau H, Capelle L, Sichez N, Denvil D, Lopes M, Sichez JP, Bitar A, Fohanno D. Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study. Brain 2002;125:199–214.

    Article  PubMed  Google Scholar 

  20. Bello L, Gallucci M, Fava M, Carrabba G, Giussani C, Acerbi F, Baratta P, Songa V, Conte V, Branca V, Stocchetti N, Papagno C, Gaini SM. Intraoperative subcortical language tract mapping guides surgical removal of gliomas involving speech areas. Neurosurgery 2007;60:67–80; discussion 62–80.

    Article  PubMed  Google Scholar 

  21. Haglund MM, Berger MS, Shamseldin M, Lettich E, Ojemann GA. Cortical localization of temporal lobe language sites in patients with gliomas. Neurosurgery 1994;34:567–76; discussion 576.

    Article  PubMed  CAS  Google Scholar 

  22. Canolty RT, Edwards E, Dalal SS, Soltani M, Nagarajan SS, Kirsch HE, Berger MS, Barbaro NM, Knight RT. High gamma power is phase-locked to theta oscillations in human neocortex. Science 2006;313:1626–8.

    Article  PubMed  CAS  Google Scholar 

  23. Keles GE, Lundin DA, Lamborn KR, Chang EF, Ojemann G, Berger MS. Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients. Journal of neurosurgery 2004;100(3):369–75.

    Article  PubMed  Google Scholar 

Download references

Authors
  1. R. M. Richardson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. S. Berger
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Canadian Research Chair in Neuroscience (Tier 1), 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Andres M. Lozano (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery) (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery)

  2. Houston Stereotactic Concepts, Inc., 2260 West Holcombe Boulevard Suite 309, Houston, Texas, 77030, USA

    Philip L. Gildenberg

  3. University of Toronto, 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Ronald R. Tasker

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Richardson, R.M., Berger, M.S. (2009). Neurophysiologic Mapping for Glioma Surgery: Preservation of Functional Areas. In: Lozano, A.M., Gildenberg, P.L., Tasker, R.R. (eds) Textbook of Stereotactic and Functional Neurosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69960-6_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69960-6_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69959-0

  • Online ISBN: 978-3-540-69960-6

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation