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MEG in Epilepsy

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Textbook of Stereotactic and Functional Neurosurgery

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Abstract

The field of magnetoencephalography (MEG) began in 1968 when Cohen used a 1-million-turn single induction coil to measure human alpha activity [1]. MEG was first applied to epilepsy by Barth et al. recording interictal spike discharges using a one-channel MEG sensor in two patients with partial seizures [2]. By 1989, multi-channel MEG sensors (37-channels) covering a relatively large region of the scalp were commercially available, making the clinical application of MEG efficient for patients with epilepsy. Currently all MEG machines are whole-head style and effectively cover most of the brain, making detection of intracerebral epileptic discharges feasible on a routine basis. This chapter describes basic physiology of MEG, characteristics of MEG spike sources, diagnosis of epilepsy, and epilepsy surgery.

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Authors
  1. A. Fujimoto
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  2. T. Akiyama
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  3. H. Otsubo
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Editor information

Editors and Affiliations

  1. Canadian Research Chair in Neuroscience (Tier 1), 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Andres M. Lozano (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery) (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery)

  2. Houston Stereotactic Concepts, Inc., 2260 West Holcombe Boulevard Suite 309, Houston, Texas, 77030, USA

    Philip L. Gildenberg

  3. University of Toronto, 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Ronald R. Tasker

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Fujimoto, A., Akiyama, T., Otsubo, H. (2009). MEG in Epilepsy. In: Lozano, A.M., Gildenberg, P.L., Tasker, R.R. (eds) Textbook of Stereotactic and Functional Neurosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69960-6_158

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  • DOI: https://doi.org/10.1007/978-3-540-69960-6_158

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69959-0

  • Online ISBN: 978-3-540-69960-6

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