Skip to main content

Toxicological Approaches for Developing Drinking Water Standards

  • Chapter
Quality and Treatment of Drinking Water II

Part of the book series: The Handbook of Environmental Chemistry ((HEC5,volume 5 / 5C))

  • 768 Accesses

Abstract

Drinking-water guidelines and standards are an important tool to protect public health and provide regulator agencies and drinking-water producers with guidance on the production of adequate and safe drinking water. The potential hazard of chemicals polluting drinking water or resulting from the treatment of water are widely understood but often overestimated in relation to microbiological hazards. This chapter will provide some insight into the toxicological evaluation which forms the basis for the derivation of guidelines for drinking-water quality as set by the World Health Organization and will touch upon some differences between health-based guidelines and national standards. Special attention will be given to the toxicological impact of chemicals present in drinking water such as inorganic pollutants, pesticides and disinfectants and disinfectant by-products.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Abbreviations

BW:

body weight

C:

concentration

2,4 D:

2,4 dichlorophenoxyacetic acid

2,4 DB:

4-(2,4 dichlorophenoxy)butyric acid

DBP:

disinfection by product

DNA:

deoxyribonucleic acid

EU:

European Union

FAO:

Food and Agricultural Organization

GV:

guideline value

LOAEL:

lowest observed adverse effect level

NOAEL:

no observed adverse effect level

OECD:

Organization for Economic Co-operation and Development

ppb:

parts per billion

TDI:

tolerable daily intake

TWI:

tolerable weekly intake

USEPA:

United States Environmental Protection Agency

WHO:

World Health Organization

References

  1. WHO (1992) Our planet, our health, Report of the WHO Commission on Health and Environment, Geneva, Switzerland

    Google Scholar 

  2. WHO (1993) Guidelines for Drinking-Water Quality, 2nd edn: Recommendations, vol 1, Geneva, Switzerland

    Google Scholar 

  3. Van Dijk-Looiijaard A (1995) In: Hrubec J. (ed), Quality and treatment of drinking water, The Handbook of Environmental Chemistry, vol 5B, Springer, Berlin Heidelberg New York

    Google Scholar 

  4. WHO (1984) Guidelines for Drinking-Water Quality, Recommendations, vol 1, Geneva, Switzerland

    Google Scholar 

  5. WHO (1996) Rolling Revision of the WHO Guidelines for Drinking-water Quality, Report WHO/EOS/ECEH/96. 1, Geneva, Switzerland

    Google Scholar 

  6. OECD (1987) Guidelines for the Testing of Chemicals, OECD, Paris, France

    Google Scholar 

  7. WHO (1991) 38th report of the Joint FAO/WHO Expert Committee on Food Additives, WHO Technical report Series 815, Geneva, Switzerland

    Google Scholar 

  8. International Programme on Chemical Safety (1992) Report on IPCS discussions on deriving guidance values for health-based exposure limits, PCS/92. 6, Geneva, Switzerland

    Google Scholar 

  9. Cotruvo JA (1988) Regulatory Toxicol and Pharmacol 8: 288

    Article  CAS  Google Scholar 

  10. Crump K, Allen B, Shipp A (1989) Health Phys. 57 (Suppl. 1): 387

    Article  CAS  Google Scholar 

  11. WHO (1987) Report of the 30th Meeting of the Joint FAO/WHO Expert Committee on Food Additives, WHO Food Additives Series 21, Geneva, Switzerland

    Google Scholar 

  12. WHO (1996) Report of the 44th Meeting of the Joint FAO/WHO Expert Committee on Food Additives, WHO Food Additive Series 35, Geneva, Switzerland

    Google Scholar 

  13. WHO (1985) Report on a WHO meeting, Environmental Health Series No. 1, WHO Regional Office, Copenhagen, Denmark

    Google Scholar 

  14. Gangolli SD, van den Brandt PA, Feron VJ, Janzowsky C, Koeman JH, Speijers GJA, Spiegelhalder B, Walker R, Wisnok JS (1994) Eur J Pharmcol, Environ Toxicol Pharmacol Section, 292: 1

    Article  CAS  Google Scholar 

  15. Kleinjans JCS, Albering HJ, Marx A, van Maanen JMS, van Agen B, ten Hoor F, Swaen GMH, Mertens PLJM (1991) Environ Health Perspect 94: 189

    Article  CAS  Google Scholar 

  16. Fawell JK (1991) BCPC Monograph No. 47, p 205

    CAS  Google Scholar 

  17. Council of the European Communities (1980) Directive relating to the quality of water intended for human consumption, 80/778/EEC, Official Journal L229, Brussels, Belgium

    Google Scholar 

  18. Galal-Gorchev H (1993) XXX, In: Craun GF (ed) Safety of water disinfection: Balancing chemical and microbiological risks, ILSI Press Washington, DC, p 463

    Google Scholar 

  19. International Agency for the Research on Cancer (1991) IARC Monograph on the evaluation of carcinogenic risks to humans, No. 52, Lyon, France

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

van Leeuwen, F.X.R. (1998). Toxicological Approaches for Developing Drinking Water Standards. In: Hrubec, J. (eds) Quality and Treatment of Drinking Water II. The Handbook of Environmental Chemistry, vol 5 / 5C. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68089-5_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-68089-5_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-14774-0

  • Online ISBN: 978-3-540-68089-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics