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Automatic Classification and Clustering of Caenorhabditis Elegans Using a Computer Vision System

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Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 2690))

Abstract

In this paper, we introduce a computer vision system for automatic classification and clustering of C. elegans according to their behavioral phenotypes. We extract three kinds of features such as worm movement, body size, and body shape. A total of 117 features are extracted for each worm. Then the features are used to build an optimal classification tree using the CART(Classification and Regression Tree). We also try to find optimal clusters by using the gap statistic and hierarchical clustering method. For the experiment, we use 860 sample worms of 9 types (wild, goa-1, nic-1, egl-19, tph-1, unc-2, unc-29, unc-36, and unc-38). According to our experimental results, average success classification rate for wild, goa-1, nic-1, and egl-19 types is 92.3% while the rate for the other types is 70.3%. And the optimal number of clusters is 8 in our case.

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References

  1. Hodkin, J.: Male phenotypes and mating efficiency in Caenorhabditis elegans. Genetics, 43–64 (1983)

    Google Scholar 

  2. Waggoner, L., et al.: Control of behavioral states by serotonin in Caenorhabditis elegans. Neuron, 203–214 (1998)

    Google Scholar 

  3. Zhou, G.T., Schafer, W.R., Schafer, R.W.: A three-state biological point process model and its parameter estimation. IEEE Trans On Signal Processing, 2698–2707 (1998)

    Google Scholar 

  4. Hastie, T., et al.: Estimating the number of clusters in a dataset via the Gap statistic. Tech. Report. Department of Statistics at Stanford University (2000)

    Google Scholar 

  5. Duda, R., Hart, P., Stork, D.: Pattern Classification. John Wiley & Sons, Inc., New York (2001)

    MATH  Google Scholar 

  6. Nah, W., Hong, S.B.: Feature Extraction for Classification of Caenorhabditis Elegans Behavioural Phenotypes. In: Chung, P.W.H., Hinde, C.J., Ali, M. (eds.) IEA/AIE 2003. LNCS, vol. 2718. Springer, Heidelberg (2003) (to be appeared)

    Chapter  Google Scholar 

  7. Gonzalez, R.C., Woods, R.E.: Digital Image Processing. Prentice Hall Inc., New Jersey (2002)

    Google Scholar 

  8. Jain, R., Kasturi, R., Schunck, B.G.: Machine Vision. McGraw-Hill Inc., New York (1995)

    Google Scholar 

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© 2003 Springer-Verlag Berlin Heidelberg

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Hong, SB., Nah, W., Baek, JH. (2003). Automatic Classification and Clustering of Caenorhabditis Elegans Using a Computer Vision System. In: Liu, J., Cheung, Ym., Yin, H. (eds) Intelligent Data Engineering and Automated Learning. IDEAL 2003. Lecture Notes in Computer Science, vol 2690. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-45080-1_100

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  • DOI: https://doi.org/10.1007/978-3-540-45080-1_100

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-40550-4

  • Online ISBN: 978-3-540-45080-1

  • eBook Packages: Springer Book Archive

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