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Tumour Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD) — Bearing Tissue

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Laser Spectroscopy VII

Part of the book series: Springer Series in Optical Sciences ((SSOS,volume 49))

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Abstract

Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced fluorescence from HPD, and b) for photodynamic therapy (HPD-PDT) using a localized HPD-assisted singlet oxygen release induced by irradiation of 630 nm laser light. This rapidly developing field has recently been reviewed by DOUGHERTY [1].

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References

  1. T.J. Dougherty: CRC Critical Reviews in Oncology/Hemato- logy, S. Davis, Ed. ( CRC Press, Florida 1984 ).

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Authors and Affiliations

  1. Department of Physics, Lund Institute of Technology, P.O. Box 118, S-221 00, Lund, Sweden

    S. Andersson, S. Montán, E. Sjöholm & S. Svanberg

  2. Wallenberg Laboratory and Department of Internal Medicine, Lund University Hospital, S-221 85, Lund, Sweden

    J. Ankerst & K. Svanberg

  3. Department of Oncology, Lund University Hospital, S-221 85, Lund, Sweden

    E. Kjellén

Authors
  1. S. Andersson
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  2. J. Ankerst
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  3. E. Kjellén
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  4. S. Montán
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  5. E. Sjöholm
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  6. K. Svanberg
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  7. S. Svanberg
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Editor information

Editors and Affiliations

  1. Department of Physics, Stanford University, 94305, Stanford, CA, USA

    Theo W. Hänsch

  2. Department of Physics, University of California, 94720, Berkeley, CA, USA

    Yuen Ron Shen

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© 1985 Springer-Verlag Berlin Heidelberg

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Andersson, S. et al. (1985). Tumour Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD) — Bearing Tissue. In: Hänsch, T.W., Shen, Y.R. (eds) Laser Spectroscopy VII. Springer Series in Optical Sciences, vol 49. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-39664-2_126

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  • DOI: https://doi.org/10.1007/978-3-540-39664-2_126

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-15253-9

  • Online ISBN: 978-3-540-39664-2

  • eBook Packages: Springer Book Archive

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