Proteins embedded in the shell of lipoproteins. They serve as scaffold for assembly of the lipoprotein particle in the endoplasmic reticulum. In addition, they control metabolism of lipoproteins in the circulation by interaction with enzymes such as lipases. Finally, apolipoproteins determine cellular uptake of the particles by interaction with specific lipoprotein receptors expressed on the surface of target cells.
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© 2008 Springer-Verlag Berlin Heidelberg New York
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(2008). Apolipoproteins. In: Offermanns, S., Rosenthal, W. (eds) Encyclopedia of Molecular Pharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-38918-7_5178
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DOI: https://doi.org/10.1007/978-3-540-38918-7_5178
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-38916-3
Online ISBN: 978-3-540-38918-7
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