Synonyms
“Pain” pathway; Nociceptive Projecting Neurons; visceral pain; angina pectoris
Characteristics
Spinothalamic tract cells - Spinal cord processing
The spinothalamic tract originates from cells in the dorsal gray matter, ascends in the contralateral anterolateral funiculus and terminates in the thalamus. The dorsal and intermediate gray matter of the spinal dorsal is made up of cells serving as interneurons and as the origin of ascending pathways that transmit visceral information to areas of the brain processing sensory information and participating in pain perception (Fig. 1) (reviewed in Willis and Westlund 1997). Of the ascending pathways, the STT is the most studied system for transmitting visceral afferent information to the brain. Axons of STT cells generally cross over in the white commissure to the contralateral side within one or two segments and then ascend generally in the anterolateral quadrant. Recent studies, however, have shown that some axons remain on the...
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References
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Foreman, R., Qin, C. (2007). Spinothalamic Tract Neurons, Visceral Input. In: Schmidt, R., Willis, W. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29805-2_4178
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