Abstract
The conjugation of steroid hormones with sulphate provides a means of excretion and inactivation of such steroids but also, and perhaps more importantly, provides a pool of steroid that can be reactivated intracellularly. The relationship of the sulphotransferase and sulphatase enzymes is discussed along with problems arising in deficiency states.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Further Reading
Geyer J, Bakhaus K, Bernhardt R, et al. The role of sulfated steroid hormones in reproductive processes. J Steroid Biochem Mol Biol. 2017;172:207–21.
Reed LJ, Purohit A, Woo LWL, Newman SP, Potter BVL. Steroid sulfatase: molecular biology, regulation and inhibition. Endocr Rev. 2005;26:171–202.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Rumsby, G. (2019). Steroid Sulphotransferase and Sulphatase Deficiency. In: Rumsby, G., Woodward, G. (eds) Disorders of Steroidogenesis. Springer, Cham. https://doi.org/10.1007/978-3-319-96364-8_13
Download citation
DOI: https://doi.org/10.1007/978-3-319-96364-8_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-96363-1
Online ISBN: 978-3-319-96364-8
eBook Packages: MedicineMedicine (R0)