Skip to main content
  • 919 Accesses

Abstract

The history of kidney transplantation is a history of modern medicine. While the early work was conducted in Europe, the postwar efforts were on both sides of the Atlantic. From the earliest days, it was recognized that transplantation involved more than mere surgery, challenging though as it was. Transplantation necessitated an understanding of the differences between species and between humans. Its history has paralleled and incorporated that of immunology, nephrology, and pharmacology. It spawned the field of histocompatibility. It was a prime generator of bioethics. Transplantation has a multidisciplinary history and is a multidisciplinary endeavor.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Carrel A. La technique operatoire des anastomoses vasculaires et la transplantation des visceres. Lyon Med. 1902;98:859.

    Google Scholar 

  2. Ullman E. Experimentelle nierentransplantation. Wien Klin Wochenschr. 1902;11:281–5.

    Google Scholar 

  3. Ullman E. Tissue and organ transplantation. Ann Surg. 1914;60:195–219.

    Article  CAS  Google Scholar 

  4. Jaboulay M. Greffe de reins au pli de coude par soudures artérielles et veineuses. Lyon Med. 1906;107:575–7.

    Google Scholar 

  5. Voronoy Y. Sobre el bloqueo del aparato reticuloendotelial del hombre en algunas formas de intoxicacion por el sublimado y sobre la transplantacion del rinon cadaverico como metodo de tratamiento de la anuria consecutive a aquella intoxicacion. Siglo Med. 1936;97:296–7.

    Google Scholar 

  6. Redman E. To save his dying sister-in-law, Charles Lindbergh invented a medical device. Smithsonian.com. September 9, 2015.

  7. Hume DM, Merrill JP, Miller BF, Thorn GW. Experiences with renal homotransplantations in the human: report of nine cases. J Clin Invest. 1955;34:327–82.

    Article  CAS  Google Scholar 

  8. Kuss R, Teinturier J, Milliez P. Quelques essais de greffe de rein chez l’homme. Mem Acad de Chir. 1951;77:755–64.

    CAS  Google Scholar 

  9. Michon L, Hamburger J, Oeconomos N, Delinotte P, Richet G, Vaysse J, Antoine B. Un etentative de transplantation renale chez l'homme: aspects medicaux et biologique. Presse Med. 1953;61:1419–23.

    CAS  PubMed  Google Scholar 

  10. Merrill JP, Murray JE, Harrison JH, Guild WR. Successful homotransplantation of the human kidney between identical twins. JAMA. 1956;160:277–82.

    Article  CAS  Google Scholar 

  11. Gibson T, Medawar PB. The fate of skin homografts in man. J Anat. 1943;77:299–310.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Owen RD. Immunogenetic consequences of vascular anastomoses between bovine twins. Science. 1945;102:400–1.

    Article  CAS  Google Scholar 

  13. Burnet FM, Fenner F. The production of antibodies. Melbourne: Macmillan; 1949.

    Google Scholar 

  14. Billingham RE, Brent L, Medawar PB. ‘Actively acquired tolerance’ of foreign cells. Nature. 1953;172:603–6.

    Article  CAS  Google Scholar 

  15. Billingham RE, Brent L, Medawar PB. Quantitative studies on tissue transplantation immunity. III Actively acquired tolerance. Phil Trans R Soc Lond B. 1956;239:357–414.

    Article  Google Scholar 

  16. Dausset J. Iso-leuco-anticorps. Acta Haematol. 1958;20:156–66.

    Article  CAS  Google Scholar 

  17. Payne R. Leukocyte agglutinins in human sera: correlation between blood transfusions and their development. AMA Arch Intern Med. 1957;99:587–606.

    Article  CAS  Google Scholar 

  18. Murray JE, Merrill JP, Dammin GJ, Dealy JB Jr, Alexandre GW, Harrison JH. Kidney transplantation in modified recipients. Ann Surg. 1962;156:337–55.

    Article  CAS  Google Scholar 

  19. Hamburger J, Vaysse J, Crosnier J, Auvert J, Lalanne CM, Hopper J Jr. Renal homotransplantation in man after radiation of the recipient: experience with six patients since 1959. Am J Med. 1962;32:854–71.

    Article  CAS  Google Scholar 

  20. Kuss R, Legrain M, Mathe G, Nedey R, Camey M. Homologous human kidney transplantation: experience with six patients. Postgrad Med J. 1962;38:528–31.

    Article  CAS  Google Scholar 

  21. Murray JE, Merrill JP, Harrison JH, Wilson RE, Dammin GJ. Prolonged survival of human-kidney homografts by immunosuppressive drug therapy. N Engl J Med. 1963;268:1315–23.

    Article  CAS  Google Scholar 

  22. Starzl TE, Marchioro TL, Waddell WR. The reversal of rejection in human renal homografts with subsequent development of homograft tolerance. Surg Gynecol Obstet. 1963;117:385–95.

    CAS  PubMed  PubMed Central  Google Scholar 

  23. Barker CF, Markmann JF. Historical overview of transplantation. Cold Spring Harb Perspect Med. 2013;3:a014977.

    Article  Google Scholar 

  24. Reemtsma K, McCracken BH, Schlegel JU, Pearl MA, Pearce CW, DeWitt CW, Smith PE, Hewitt RL, Flinner RL, Creech O Jr. Renal heterotransplantation in man. Ann Surg. 1964;160:384–410.

    Article  CAS  Google Scholar 

  25. Williams GM, Hume DM, Hudson RP Jr, Morris PJ. Hyperacute renal-homograft rejection in man. N Engl J Med. 1968;279:611–8.

    Article  CAS  Google Scholar 

  26. Patel R, Terasaki PI. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med. 1969;280:735–9.

    Article  CAS  Google Scholar 

  27. Terasaki PI, McClelland JD. Microdroplet assay of human serum cytotoxins. Nature. 1964;204:998–1000.

    Article  CAS  Google Scholar 

  28. Opelz G, Sengar DP, Mickey MR, Terasaki PI. Effect of blood transfusions on subsequent kidney transplants. Transplant Proc. 1973;5:253–9.

    CAS  PubMed  Google Scholar 

  29. Salvatierra O Jr, Vincenti F, Amend W, Potter D, Iwaki Y, Opelz G, Terasaki P, Duca R, Cochrum K, Hanes D, Stoney RJ, Feduska NJ. Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach. Ann Surg. 1980;192:543–52.

    Article  Google Scholar 

  30. Ting A, Morris P. Matching for B-cell antigens of the HLA-DR series in cadaver renal transplantation. Lancet. 1978;311:575–7.

    Article  Google Scholar 

  31. Delmonico FL. The concept of death and deceased organ donation. Int J Organ Transplant Med. 2010;1:15–20.

    CAS  PubMed  PubMed Central  Google Scholar 

  32. United States. National Organ Transplant Act: Public Law 98-507. US Statut Large. 1984;98:2339–48.

    Google Scholar 

  33. Montgomery RA. One kidney for life. Am J Transplant. 2014;14:1473–4.

    Article  CAS  Google Scholar 

  34. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, Held PJ, Port FK. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341:1725–30.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to John D. Scandling .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Scandling, J.D. (2019). History of Renal Transplantation. In: Sher, Y., Maldonado, J. (eds) Psychosocial Care of End-Stage Organ Disease and Transplant Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-94914-7_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-94914-7_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-94913-0

  • Online ISBN: 978-3-319-94914-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics