Skip to main content

Enteral and Parenteral Nutrition: Considerations for Visceral Transplant Patients

  • Chapter
  • First Online:
Psychosocial Care of End-Stage Organ Disease and Transplant Patients

Abstract

Intestinal failure (IF) is a complex malabsorptive disorder that not only leads to multiple health-related complications, but is also closely associated with a reduced quality of life (QOL) due to an intolerance of an oral diet, usually resulting in complete reliance on alternative means of nutrition support. Severe reduction of gut function, impaired intestinal transit time, hypophagia, and almost complete malabsorption of oral macro- and micronutrients are defining characteristics of IF. Due to these complications, patients with IF are often dependent on parenteral nutrition (PN) as the intravenous method for nutrition supplementation to sustain health. Chronic use of PN, however, may result in metabolic and infectious complications. For patients who have irreversible IF and experience complications from PN, multivisceral and intestinal (MV/I) transplantation may be necessary for long-term survival. In addition, protein-calorie malnutrition (PCM) negatively impacts all solid organ and bone marrow transplant outcomes; therefore, a referral to a registered dietitian for nutrition assessment and intervention is crucial to optimize pre-transplant and post-transplant nutrition care. The ultimate goal of MV/I transplantation is to optimize a patient’s QOL by establishing full nutritional autonomy, with a full wean from PN and transition to enteral nutrition (EN) and oral diet.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Pironi L, Arends J, Baxter J, et al. ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. Clin Nutr. 2015;34:171–80.

    Article  Google Scholar 

  2. Pironi L, Arends J, Bozzetti F, et al. ESPEN guidelines on chronic intestinal failure in adults. Clin Nutr. 2016;35:247–307.

    Article  Google Scholar 

  3. Winkler M, DiMaria-Ghalili R, Guenter P, Resnick H, Robinson L, Lyman B, Ireton-Jones C, Banchik L, Steiger E. Characteristics of a cohort of home parenteral nutrition patients at the time of enrollment in the sustain registry. J Parenter Enter Nutr. 2016;40:1140–9.

    Article  Google Scholar 

  4. Grant D, Abu-Elmagd K, Mazariegos G, Vianna R, Langnas A, Mangus R, Farmer D, Lacaille F, Iyer K, Fishbein T. Intestinal transplant registry report: global activity and trends. Am J Transplant. 2014;15:210–9.

    Article  Google Scholar 

  5. Matarese L, Costa G, Bond G, Stamos J, Koritsky D, O’Keefe S, Abu-Elmagd K. Therapeutic efficacy of intestinal and multivisceral transplantation: survival and nutrition outcome. Nutr Clin Pract. 2007;22:474–81.

    Article  Google Scholar 

  6. Jensen G, Bistrian B, Roubenoff R, Heimburger D. Malnutrition syndromes: a conundrum vs continuum. J Parenter Enter Nutr. 2009;33:710–6.

    Article  Google Scholar 

  7. White J, Guenter P, Jensen G, Malone A, Schofield M. Consensus statement of the academy of nutrition and dietetics/American Society for Parenteral and Enteral Nutrition: characteristics recommended for the identification and documentation of adult malnutrition (undernutrition). J Acad Nutr Diet. 2012;112:730–8.

    Article  Google Scholar 

  8. Jensen G, Compher C, Sullivan D, Mullin G. Recognizing malnutrition in adults. J Parenter Enter Nutr. 2013;37:802–7.

    Article  Google Scholar 

  9. Hasse J. Nutrition assessment and support of organ transplant recipients. J Parenter Enter Nutr. 2001;25:120–31.

    Article  CAS  Google Scholar 

  10. Carey E. Sarcopenia in solid organ transplantation. Nutr Clin Pract. 2014;29:159–70.

    Article  Google Scholar 

  11. Stephenson G, Moretti E, El-Moalem H, Clavien P, Tuttle-Newhall J. Malnutrition in liver transplant patients. Transplantation. 2001;72:666–70.

    Article  CAS  Google Scholar 

  12. Merli M, Giusto M, Giannelli V, Lucidi C, Riggio O. Nutritional status and liver transplantation. J Clin Exp Hepatol. 2011;1:190–8.

    Article  Google Scholar 

  13. Makhija S, Baker J. The subjective global assessment: a review of its use in clinical practice. Nutr Clin Pract. 2008;23:405–9.

    Article  Google Scholar 

  14. Lacey K, Pritchett E. Nutrition care process and model: ADA adopts road map to quality care and outcomes management. J Am Diet Assoc. 2003;103:1061–72.

    Article  Google Scholar 

  15. Esper D. Utilization of nutrition-focused physical assessment in identifying micronutrient deficiencies. Nutr Clin Pract. 2015;30:194–202.

    Article  CAS  Google Scholar 

  16. Klein C, Stanek G, Wiles C. Overfeeding macronutrients to critically ill adults. J Am Diet Assoc. 1998;98:795–806.

    Article  CAS  Google Scholar 

  17. Staun M, Pironi L, Bozzetti F, et al. ESPEN guidelines on parenteral nutrition: home parenteral nutrition (HPN) in adult patients. Clin Nutr. 2009;28:467–79.

    Article  Google Scholar 

  18. Skallerup A, Nygaard L, Olesen S, Vinter-Jensen L, Køhler M, Rasmussen H. Can we rely on predicted basal metabolic rate in patients with intestinal failure on home parenteral nutrition? J Parenter Enter Nutr. 2016;41:1139–45.

    Article  Google Scholar 

  19. AraĂºjo E, Suen V, Marchini J, Vannucchi H. Ideal weight better predicts resting energy expenditure than does actual weight in patients with short bowel syndrome. Nutrition. 2007;23:778–81.

    Article  Google Scholar 

  20. Davila J, Konrad D. Metabolic complications of home parenteral nutrition. Nutr Clin Pract. 2017;32:753–68.

    Article  Google Scholar 

  21. Limketkai B, Choe M, Patel S, Shah N, Medici V. Nutritional risk factors in the pathogenesis of parenteral nutrition-associated liver disease. Curr Nutr Rep. 2017;6:281–90.

    Article  CAS  Google Scholar 

  22. Weimann A, Braga M, Harsanyi L, et al. ESPEN guidelines on enteral nutrition: surgery including organ transplantation. Clin Nutr. 2006;25:224–44.

    Article  CAS  Google Scholar 

  23. Matarese LE. Nutrition interventions before and after adult intestinal transplantation: the Pittsburgh experience. Pract Gastroenterol. 2010;34(11):11–30.

    Google Scholar 

  24. Rovera G, Schoen R, Goldbach B, Janson D, Bond G, Rakela J, Graham T, O’Keefe S, Abu-Elmagd K. Intestinal and multivisceral transplantation: dynamics of nutritional management and functional autonomy. J Parenter Enter Nutr. 2003;27:252–9.

    Article  Google Scholar 

  25. Obayashi P. Food safety for the solid organ transplant patient. Nutr Clin Pract. 2012;27:758–66.

    Article  Google Scholar 

  26. Bonnes S, Salonen B, Hurt R, McMahon M, Mundi M. Parenteral and enteral nutrition—from hospital to home: will it be covered? Nutr Clin Pract. 2017;32:730–8.

    Article  Google Scholar 

  27. DiMartini A, Rovera G, Graham T, Furukawa H, Todo S, Funovits M, Lu S, Abu-Elmagd K. Quality of life after small intestinal transplantation and among home parenteral nutrition patients. J Parenter Enter Nutr. 1998;22:357–62.

    Article  CAS  Google Scholar 

  28. Avitzur Y, Miserachs M. Quality of life on long-term parenteral nutrition. Curr Opin Organ Transplant. 2018;23:1–8.

    Article  Google Scholar 

  29. Richards D, Irving M. Assessing the quality of life of patients with intestinal failure on home parenteral nutrition. Gut. 1997;40:218–22.

    Article  CAS  Google Scholar 

  30. Abu-Elmagd K, Kosmach-Park B, Costa G, et al. Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation. Ann Surg. 2012;256:494–508.

    Article  Google Scholar 

  31. Pironi L, Baxter J, Lauro A, Guidetti M, Agostini F, Zanfi C, Pinna A. Assessment of quality of life on home parenteral nutrition and after intestinal transplantation using treatment-specific questionnaires. Am J Transplant. 2012;12:S60–6.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Neha D. Shah MPH, RD, CNSC .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Shah, N.D., Stroebe, M. (2019). Enteral and Parenteral Nutrition: Considerations for Visceral Transplant Patients. In: Sher, Y., Maldonado, J. (eds) Psychosocial Care of End-Stage Organ Disease and Transplant Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-94914-7_31

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-94914-7_31

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-94913-0

  • Online ISBN: 978-3-319-94914-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics