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Egypt and Autism

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Encyclopedia of Autism Spectrum Disorders

Historical Background

Egypt is located in North Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip. Genetic diseases in Egyptians have been known since the days of the pharaohs as recorded in the ancient history. Gene flow to Egyptian population occurred from Greco-Roman, Arab, Turkish, French, and English settlers. For reasons of custom, tradition, culture, and socioeconomic benefit, consanguineous marriages occur in approximately half, and first-cousin marriages occur in one third of Egyptians (Yamamah 2012). The population of the region is characterized by large family size, high maternal and paternal age, and a high level of inbreeding with consanguinity rates. Women are continuing to bear children until menopause increasing the predisposition to inherited disorders.

Developing countries are facing an alarming gap between innovations in childhood learning and developmental disabilities (LDD) research and their delivery to communities. Important problems...

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References and Reading

  • Abdel Razek, A., Mazroa, J., & Baz, H. (2013). Assessment of white matter integrity of autistic preschool children with diffusion weighted MR imaging. Brain and Development, 36(1), 28–34.

    Google Scholar 

  • Abdel, H., Ramadan, E., & Elshair, I. (2012). The effect of educational program on caregivers (knowledge and practicing) toward their autistic children. Journal of American Science, 8(1), 1–6. http://www.jofamericanscience.org

  • Abrahams, B. S., & Geschwind, D. H. (2008). Advances in ASD genetics: On the threshold of a new neurobiology. Nature Reviews. Genetics, 9, 341–355.

    PubMed  PubMed Central  Google Scholar 

  • Allam, H., ElDine, N. G., & Helmy, G. (2008). Scalp acupuncture effect on language development in children with autism: A pilot study. Journal of Alternative and Complementary Medicine, 14(2), 109–114.

    PubMed  Google Scholar 

  • Al-Farsi, Y. M., Al-Sharbati, M. M., Al-Farsi, O. M., Al-Shafaee, M. S., Brooks, D. R., Waly, M. I. (2010). Brief report: prevalence of autistic spectrum disorders in the sultanate of oman. Journal of Autism and Developmental Disorders, 41(6), 821–825.

    Google Scholar 

  • Al-Salehi, S. M., Al-Hifthy, E. H., & Ghaziuddin, M. (2009). Autism in Saudi Arabia: Presentation, clinical correlates and comorbidity. Transcultural Psychiatry, 46(2), 340–347.

    PubMed  Google Scholar 

  • Cohen, N. J., & Volkmar, F. R. (2005). Handbook of autism and pervasive developmental disorders (2nd ed.). New York: Wiley.

    Google Scholar 

  • Eapen, V., MabroukAA Zoubeidi, T., Yunis, F. (2007). Prevalence of pervasive developmental disorders in preschool children in the UAE. Journal of Tropical Pediatrics, 53(3), 202–205.

    Google Scholar 

  • El Baz, F., Ismael, N., & Nour El-Din, S. (2011). Risk factors for autism: An Egyptian study. The Egyptian Journal of Medical Human Genetics, 12, 31–38.

    Google Scholar 

  • Elbahnasawy, H., & Girgis, M. (2011). Counseling for mothers to cope with their autistic children. Journal of American Science, 7(7), 183–192.

    Google Scholar 

  • Elsabbagh, M., Divan, G., Koh, Y.-J., Kim, Y. S., Kauchali, S., Marcín, C., Montiel-Nava, C., Pate, V., Paula, C. S., Wang, C., Yasamy, M. T., & FombonneGlobal, E. (2012). Prevalence of autism and other pervasive developmental disorders. Autism Research, 5(3), 160–179.

    PubMed  PubMed Central  Google Scholar 

  • Gebril, O., & Meguid, N. (2011). HFE gene polymorphisms and the risk for autism in Egyptian children and impact on the effect of oxidative stress. Disease Markers, 31(5), 289–294.

    PubMed  PubMed Central  Google Scholar 

  • Helping Egyptian children with autism – The Egyptian Gazette 213.158.162.45/~egyptian/index.php?action = news&id = 18159…May 14, 2011 – Dr Shawkia S. Abdel-Halim of the Nutritional Institute

    Google Scholar 

  • Hong, K. M., Yamazaki, K., & Banaag, C. G. (2004). Systems of care in Asia. In H. Remschmidt, M. Belfer, & I. Goodyer (Eds.), Facilitating pathways: Care, treatment and prevention in Child and Adolescent Mental Health (pp. 58–70). Berlin: Springer.

    Google Scholar 

  • Hussein, H., Taha, G. H., & Almanasef, A. (2011). Characteristics of autism spectrum disorders in a sample of Egyptian and Saudi patients: Transcultural cross sectional study. Child and Adolescent Psychiatry and Mental Health, 5, 34.

    PubMed  PubMed Central  Google Scholar 

  • Hussein, H., Shaker, N., El-Sheikh, M., & Ramy, H. A. (2012). Pathways to child mental health services among patients in an urban clinical setting in Egypt. Psychiatric Services, 63(12), 1225–1230.

    PubMed  Google Scholar 

  • Ibrahim, K. S., & El-Sayed, E. M. (2012). Proposed remedies for some developmental disorders. Toxicology and Industrial Health, 29(4), 367–384.

    PubMed  Google Scholar 

  • Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217.

    Google Scholar 

  • Kawashti, M. I., Amin, O. R., & Rowehy, N. G. (2006). Possible immunological disorders in autism: Concomitant autoimmunity and immune tolerance. Egyptian Journal of Immunology, 13(1), 99–104.

    PubMed  Google Scholar 

  • King, G., Zwaigenbaum, L., King, S., & Baxter, D. (2006). A qualitative investigation of changes in the belief systems of families of children with autism or Down syndrome. Child Care, Health & Development, 3, 353–368.

    Google Scholar 

  • Leibson, C. L., Katusic, S. K., Barbaresi, W. J., et al. (2001). Use and costs of medical care for children and adolescents with and without attention-deficit-hyperactivity disorder. JAMA, 285, 60–66.

    PubMed  Google Scholar 

  • Longe, C. I., & Asuni, T. (1972). Four cases of Infantile autism in Nigerian children. Paper presented at Third Pan African Psychiatric Conference, Khartoum, 1972.

    Google Scholar 

  • Lotter, V. (1978). Childhood autism in Africa. Journal of Child Psychology and Psychiatry, 19(3), 231–244.

    PubMed  Google Scholar 

  • Lotter, V. (1980). Cross cultural perspectives on childhood autism. Journal of Tropical Pediatrics, 26(4), 131–133.

    PubMed  Google Scholar 

  • Meguid, N. A., Dardir, A. A., El-Sayed E. M., Ahmed H. H., Hashish A. F., Ezzat A. (2010). Homocysteine and oxidative stress in Egyptian children with Down syndrome. Clin Biochem. 43(12), 963–967.

    PubMed  Google Scholar 

  • Meguid, N. A., Hashish, A. F., Anwar, M., & Sidhom, G. (2010a). Assessment of 25-Hydroxy and 1, 25-Dihydroxy vitamin D in Egyptian children with autism. Journal of Alternative and Complementary Medicine, 16(6), 641–645.

    PubMed  Google Scholar 

  • Meguid, N. A., Fahim, C., Uicheul, Y., Nashaat, N., Samir, A., Mancini-Marie, A., Brandner, C., & Evans, A. C. (2010b). Brian morphology in autism and Fragile X syndrome correlates with Social IQ. Journal of Child Neurology, 25(5), 599–608.

    PubMed  Google Scholar 

  • Meguid, N. A., Dardir, A. A., Abdel-Raouf, E. R., & Hashish, A. (2011). Evaluation of oxidative stress in autism: Defective antioxidant enzymes and increased lipid peroxidation. Biological Trace Element Research, 143(1), 58–65.

    PubMed  Google Scholar 

  • Meguid, N. A., Ehab R Abdel-Raouf, Ahmed A Dardir, Mostafa K. (2007): Prevalence of fragile X syndrome among school-age Egyptian males. World J Pediatr. 3(4):271–275.

    Google Scholar 

  • Mostafa, G. A., & Kitchener, N. (2009). Serum anti-nuclear antibodies as a marker of autoimmunity in Egyptian autistic children. Pediatric Neurology, 40(2), 107–112.

    PubMed  Google Scholar 

  • Mostafa, G. A., El-Sayed, Z. A., El-Aziz, M. M., & El-Sayed, M. F. (2008). Serum anti-myelin-associated glycoprotein antibodies in Egyptian autistic children. Journal of Child Neurology, 23(12), 1413–1418.

    PubMed  Google Scholar 

  • Mostafa, G. A., Shehab, A. A. (2010): The link of C4B null allele to autism and to a family history of autoimmunity in Egyptian autistic children. Journal of Neuroimmunology, 223(1–2):115–9.

    Google Scholar 

  • Mostafa, G. A., Shehab, A. A., Al-Ayadhi, L. Y. (2012). The link between some alleles on human leukocyte antigen system and autism in children. Journal of Neuroimmunology, 255(1–2):70–4.

    Google Scholar 

  • Mostafa, G. A., Shehab, A. A., & Al-Ayadhi, L. Y. (2013). The link between some alleles on human leukocyte antigen system and autism in children. Journal of Neuroimmunology, 255(1–2), 70–74.

    PubMed  Google Scholar 

  • Novarino, G., El-Fishawy, P., Kayserili, H., Meguid, N. A., Scott, E. M., Schroth, J., Silhavy, J. L., Kara, M., Khalil, R. O., Ben-Omran, T., Ercan-Sencicek, A. G., Hashish, A. F., Sanders, S. J., Gupta, A. R., Hashem, H. S., Matern, D., Gabriel, S., Sweetman, L., Rahimi, Y., Harris, R. A., State, M. W., & Gleeson, J. G. (2012). Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy. Science, 338, 394–397.

    PubMed  PubMed Central  Google Scholar 

  • Obaid, M. (2012). Parental attitudes towards autistic child. European Journal of Social Sciences, 31(1), 103–114.

    Google Scholar 

  • Okasha, A. (2004). Focus on psychiatry in Egypt. British Journal of Psychiatry, 185, 266–272.

    Google Scholar 

  • Robertson, B., Mandlhate, C., & Seif El-Din, A. (2004). Systems of care in Africa. In H. Remschmidt, M. Belfer, & I. Goodyer (Eds.), Facilitating pathways: Care, treatment and prevention in child and adolescent mental health (pp. 71–88). Berlin: Springer.

    Google Scholar 

  • Samadi, S. A., & McConkey, R. (2011). Autism in Developing Countries: Lessons from Iran. Autism Research and Treatment, 1–11.

    Google Scholar 

  • Seif Eldin, A., Habib, D., Noufal, A., Farrag, S., Bazaid, K., Al-Sharbati, M., Badr, H., Moussa, S., Essali, A., & Gaddour, N. (2008). Use of M-CHAT for a multinational screening of young children with autism in the Arab countries. International Review of Psychiatry, 20(3), 281–289.

    PubMed  Google Scholar 

  • Yamamah, G., Abdel-Raouf, E., Talaat, A., Saad-Hussein, A., Hamamy, H., Meguid, N. A. (2012). Prevalence of consanguineous marriages in south Sinai, Egypt. J Biosoc Sci, 14, 1–9.

    Google Scholar 

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Correspondence to Nagwa Abdel Meguid .

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Meguid, N.A. (2021). Egypt and Autism. In: Volkmar, F.R. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-91280-6_102026

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