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Childhood Diarrhea in the Maghreb Arabic Union and Health Benefits of Rotavirus Vaccination

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Handbook of Healthcare in the Arab World

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Abstract

Diarrhea is a leading cause of morbidity and mortality among children under 5 in developing countries. Two rotavirus vaccines have been licensed in more than 100 countries around the world since 2006. In the Arab Maghreb countries, rotavirus vaccines were initially introduced in Morocco in 2010 and then in Libya and Mauritania in 2013 and 2014, respectively. This chapter describes the burden of childhood diarrhea diseases and the health benefits of rotavirus vaccination in the Arab Maghreb countries, with a view to restricting the evolution of the disease and to identify features differentiating its epidemiology. Information provided in this chapter were extracted from the World Health Organization’s weekly reports and information issued by the ministries of health in these countries as well as from published papers. The data shows a high rate of diarrhea morbidity among children less than 5 years of age and highlights the benefits of vaccination in reducing the health burden of severe childhood diarrhea. This study should provide evidence that can be used to sustain vaccine use not only in the Maghreb Arabic Union but also in the Arabic region in general.

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References

  • Ahmed MLCB, Weddih A, Benhafid M, Bollahi MA, Sidatt M, Makhalla K, Mokdad AH, Heukelbach J, Filali-Maltouf A (2018) Hospitalizations and deaths associated with diarrhea and respiratory diseases among children aged 0–5 years in a referral Hospital of Mauritania. Trop Med Infect Dis 3. https://doi.org/10.3390/tropicalmed3030103

  • Ahmed M-LC, Heukelbach J, Weddih A, Filali-Maltouf A, Sidatt M, Makhalla K, Ahmed ACC, El-Mami MV, Tate JE, Parashar UD (2019) Reduction of hospitalizations with diarrhea among children aged 0–5 years in Nouakchott, Mauritania, following the introduction of rotavirus vaccine. Vaccine 37(11):1407–1411

    Article  Google Scholar 

  • Al Awaidy SA, Bawikar S, Al Busaidy S, Baqiani S, Al Abedani I, Varghese R, Abdoan HS, Al Abdoon H, Bhatnagar S, Al Hasini KS (2009) Considerations for introduction of a rotavirus vaccine in Oman: rotavirus disease and economic burden. J Infect Dis 200:S248–S253

    Article  Google Scholar 

  • Al-Ghamdi MA, Bentham G, Hunter PR (2009) Environmental risk factors for diarrhoea among male schoolchildren in Jeddah City, Saudi Arabia. J Water Health 7:380–391

    Article  Google Scholar 

  • Ali MB, Ghenghesh KS, Aissa RB, Abuhelfaia A, Dufani M (2005) Etiology of childhood diarrhea in Zliten, Libya. Saudi Med J 26:1759–1765

    PubMed  Google Scholar 

  • Al-Mohammed HI, Amin TT, Aboulmagd E, Hablus HR, Zaza BO (2010) Prevalence of intestinal parasitic infections and its relationship with socio–demographics and hygienic habits among male primary school children in Al–Ahsa, Saudi Arabia. Asian Pac J Trop Med 3:906–912

    Article  Google Scholar 

  • Andrews JR, Leung DT, Ahmed S, Malek MA, Ahmed D, Begum YA, Qadri F, Ahmed T, Faruque ASG, Nelson EJ (2017) Determinants of severe dehydration from diarrheal disease at hospital presentation: evidence from 22 years of admissions in Bangladesh. PLoS Negl Trop Dis 11:e0005512. https://doi.org/10.1371/journal.pntd.0005512

    Article  PubMed  PubMed Central  Google Scholar 

  • Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A, Flemban H, Al-Nassir WN, Balkhy HH, Al-Hakeem RF (2013) Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 13:752–761

    Article  Google Scholar 

  • Bado AR, Susuman AS, Nebie EI (2016) Trends and risk factors for childhood diarrhea in sub-Saharan countries (1990–2013): assessing the neighborhood inequalities. Glob Health Action 9:30166

    Article  Google Scholar 

  • Bbaale E (2011) Determinants of diarrhoea and acute respiratory infection among under-fives in Uganda. Australas Med J 4:400

    Article  CAS  Google Scholar 

  • Bendib A, Dekkar N, Lamdjadani N (1993) Factors associated with neonatal, infant and child mortality. Results of a national survey in Algeria. Arch Fr Pediatr 50:741–747

    CAS  PubMed  Google Scholar 

  • Benhafid M, Youbi M, Klena JD, Gentsch JR, Teleb N, Widdowson M-A, ElAouad R (2009) Epidemiology of rotavirus gastroenteritis among children< 5 years of age in Morocco during 1 year of sentinel hospital surveillance, June 2006–May 2007. J Infect Dis 200:S70–S75

    Article  Google Scholar 

  • Benhafid M, Rguig A, Trivedi T, Elqazoui M, Teleb N, Mouane N, Maltouf AF, Parashar U, Patel M, Aouad RE (2012) Monitoring of rotavirus vaccination in Morocco: establishing the baseline burden of rotavirus disease. Vaccine 30:6515–6520. https://doi.org/10.1016/j.vaccine.2012.08.058

    Article  PubMed  Google Scholar 

  • Benhafid M, Elomari N, Idrissi MA, Rguig A, Gentsch JR, Parashar U, ElAouad R (2015) Effect of monovalent rotavirus vaccine on rotavirus disease burden and circulating rotavirus strains among children in Morocco. J Med Virol 87:944–956. https://doi.org/10.1002/jmv.24122

    Article  PubMed  Google Scholar 

  • Benmessaoud R, Jroundi I, Nezha M, Moraleda C, Tligui H, Seffar M, Alvarez Martínez MJ, Pons MJ, Chaacho S, Hayes EB (2015) Aetiology, epidemiology and clinical characteristics of acute moderate-to-severe diarrhoea in children under 5 years of age hospitalized in a referral paediatric hospital in Rabat, Morocco. J Med Microbiol 64(Pt 1):84–92. Society for General Microbiology

    Article  Google Scholar 

  • Boschi-Pinto C, Velebit L, Shibuya K (2008) Estimating child mortality due to diarrhoea in developing countries. Bull World Health Organ 86:710–717

    Article  Google Scholar 

  • Bourrous M, Elmjati H, Amine M, El Omari J, Bouskraoui M (2010) Diarrheal disease in the region of Marrakech, Morocco. Med Trop (Mars) 70:145–148

    CAS  Google Scholar 

  • Chouikha A, Fodha I, Noomen S, Bouzid L, Mastouri M, Peenze I, De Beer M, Dewar J, Geyer A, Sfar T, Gueddiche N, Messaadi F, Trabelsi A, Boujaafar N, Steele AD (2007) Group A rotavirus strains circulating in the eastern center of Tunisia during a ten-year period (1995–2004). J Med Virol 79:1002–1008. https://doi.org/10.1002/jmv.20919

    Article  CAS  PubMed  Google Scholar 

  • Colvin CJ, Smith HJ, Swartz A, Ahs JW, de Heer J, Opiyo N, Kim JC, Marraccini T, George A (2013) Understanding careseeking for child illness in sub-Saharan Africa: a systematic review and conceptual framework based on qualitative research of household recognition and response to child diarrhoea, pneumonia and malaria. Soc Sci Med 86:66–78

    Article  Google Scholar 

  • Das JK, Salam RA, Bhutta ZA (2014) Global burden of childhood diarrhea and interventions. Curr Opin Infect Dis 27:451–458

    Article  Google Scholar 

  • Ghanim MA, Taher IAA, Ahmaida AI, Tobgi RS (2003) Etiology of childhood diarrhea in Benghazi, Libya. Garyounis Med J 20:22–24

    Google Scholar 

  • Gusbi MM (2007) Aetiology of acute diarrhoea in hospitalized children Tripoli, Libya. University of Salford

    Google Scholar 

  • Hassine-Zaafrane M, Sdiri-Loulizi K, Salem IB, Kaplon J, Ayouni S, Ambert-Balay K, Sakly N, Pothier P, Aouni M (2011) The molecular epidemiology of circulating rotaviruses: three-year surveillance in the region of Monastir, Tunisia. BMC Infect Dis 11:266. https://doi.org/10.1186/1471-2334-11-266

    Article  PubMed  PubMed Central  Google Scholar 

  • Hay SI (2017) Burden of diarrhea in the Eastern Mediterranean Region, 1990–2015: findings from the Global Burden of Disease 2015 Study. Int J Public Health 63(Suppl 1):109–121

    Google Scholar 

  • Howidi M, Al Kaabi N, El Khoury AC, Brandtmüller A, Nagy L, Richer E, Haddadin W, Miqdady MS (2012) Burden of acute gastroenteritis among children younger than 5 years of age – a survey among parents in the United Arab Emirates. BMC Pediatr 12:74

    Article  Google Scholar 

  • Khalil M, Azhar E, Kao M, Al-Kaiedi N, Alhani H, Al Olayan I, Pawinski R, Gopala K, Kandeil W, Anis S, Van Doorn LJ, DeAntonio R (2015) Gastroenteritis attributable to rotavirus in hospitalized Saudi Arabian children in the period 2007–2008. Clin Epidemiol 7:129–137. https://doi.org/10.2147/CLEP.S69502

    Article  PubMed  PubMed Central  Google Scholar 

  • Khoury H, Ogilvie I, El Khoury AC, Duan Y, Goetghebeur MM (2011) Burden of rotavirus gastroenteritis in the Middle Eastern and North African pediatric population. BMC Infect Dis 11:9. https://doi.org/10.1186/1471-2334-11-9

    Article  PubMed  PubMed Central  Google Scholar 

  • Knope K, Giele C (2013) Increasing notifications of dengue in Australia related to overseas travel, 1991 to 2012. Commun Dis Intell Q Rep 37:E55

    PubMed  Google Scholar 

  • Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J, Lawn JE, Cousens S, Mathers C, Black RE (2016) Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet 388:3027–3035

    Article  Google Scholar 

  • Marino DD (2007) Water and food safety in the developing world: global implications for health and nutrition of infants and young children. J Am Diet Assoc 107:1930–1934. https://doi.org/10.1016/j.jada.2007.08.013

    Article  PubMed  Google Scholar 

  • Musaiger AO, Hassan AS, Obeid O, Musaiger AO, Hassan AS, Obeid O (2011) The paradox of nutrition-related diseases in the Arab countries: the need for action. Int J Environ Res Public Health 8:3637–3671. https://doi.org/10.3390/ijerph8093637

    Article  PubMed  PubMed Central  Google Scholar 

  • Prüss-Üstün A, Bonjour S, Corvalán C (2008) The impact of the environment on health by country: a meta-synthesis. Environ Health 7:7

    Article  Google Scholar 

  • Publication des données du SNIS. http://www.snisrim.org/websnis/Pg_Publication_SNIS/TAwAACeYtwNISGxOcndTQ1BYAwA. Accessed 13 Oct 2018

  • Sdiri-Loulizi K, Gharbi-Khélifi H, de Rougemont A, Chouchane S, Sakly N, Ambert-Balay K, Hassine M, Guédiche MN, Aouni M, Pothier P (2008) Acute infantile gastroenteritis associated with human enteric viruses in Tunisia. J Clin Microbiol 46:1349–1355. https://doi.org/10.1128/JCM.02438-07

    Article  PubMed  PubMed Central  Google Scholar 

  • Sy I, Keita M, Lo B, Tanner M, Cisse G (2012) Prevalence of infantile diarrhea in districts of Nouakchott (Mauritania) in 2008: analysis of local hygiene. Med Sante Trop 22:217–219. https://doi.org/10.1684/mst.2012.0031

    Article  CAS  PubMed  Google Scholar 

  • Sy I, Traore D, Niang Diene A, Kone B, Lo B, Faye O, Utzinger J, Cisse G, Tanner M (2017) Water, sanitation and diarrheal risk in Nouakchott Urban Community, Mauritania. Sante Publique 29:741–750. https://doi.org/10.3917/spub.175.0741

    Article  PubMed  Google Scholar 

  • Szajewska H, Dziechciarz P (2010) Gastrointestinal infections in the pediatric population. https://insights.ovid.com/crossref?an=00001574-201001000-00008. Accessed 15 Oct 2018

  • Tate JE, Patel MM, Steele AD, Gentsch JR, Payne DC, Cortese MM, Nakagomi O, Cunliffe NA, Jiang B, Neuzil KM (2010) Global impact of rotavirus vaccines. Expert Rev Vaccines 9:395–407

    Article  Google Scholar 

  • Touray S, Ba H, Ba O, Koita M, Salem CBOA, Keita M, Traore D, Sy I, Winkler MS, Utzinger J, Cisse G (2012) Absence of dry season Plasmodium parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in preschool-aged children in Kaedi, southern Mauritania. Parasit Vectors 5:193. https://doi.org/10.1186/1756-3305-5-193

    Article  PubMed  PubMed Central  Google Scholar 

  • Traore D, Sy I, Utzinger J, Epprecht M, Kengne IM, Lo B, Odermatt P, Faye O, Cisse G, Tanner M (2013) Water quality and health in a Sahelian semi-arid urban context: an integrated geographical approach in Nouakchott, Mauritania. Geospat Health 8:53–63. https://doi.org/10.4081/gh.2013.54

    Article  PubMed  Google Scholar 

  • UNICEF (2015) Enquête par Grappes à Indicateurs Multiples (MICS)

    Google Scholar 

  • UNICEF, WHO (2009) Diarrhea: why children are still dying and what can be done. The United Nations Children’s Fund. World Health Organization, Geneva, pp 1–58

    Google Scholar 

  • Urbani C, Toure A, Hamed AO, Albonico M, Kane I, Cheikna D, Hamed NO, Montresor A, Savioli L (1997) Intestinal parasitic infections and schistosomiasis in the valley of the Senegal river in the Islamic Republic of Mauritania. Med Trop (Mars) 57:157–160

    CAS  Google Scholar 

  • Vallieres F, Cassidy EL, McAuliffe E, Isselmou SO, Hamahoullah MS, Lang J (2013) Where are the gaps in improving maternal and child health in Mauritania? The case for contextualised interventions: a cross sectional study. Pan Afr Med J 14:97. https://doi.org/10.11604/pamj.2013.14.97.2292

    Article  PubMed  PubMed Central  Google Scholar 

  • Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, Casey DC, Charlson FJ, Chen AZ, Coates MM (2016) Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388:1459–1544

    Article  Google Scholar 

  • WHO (2018) Cholera – Algeria. WHO. http://www.who.int/csr/don/14-september-2018-cholera-algeria/en/. Accessed 24 Feb 2019

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Authors and Affiliations

  1. The Mauritania Association for Scientific Research Development (AMDRS), University of Nouakchott Al-Assriya (UNA), Nouakchott, Mauritania

    Mohamed Lemine Cheikh Brahim Ahmed & Abdallah El-Vally

  2. Research Unity on Public Health and Epidemiology (URSPE), Faculty of Medicine, University of Nouakchott Al-Assriya (UNA), Nouakchott, Mauritania

    Mohamed Lemine Cheikh Brahim Ahmed & Abdallah El-Vally

Authors
  1. Mohamed Lemine Cheikh Brahim Ahmed
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  2. Abdallah El-Vally
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Corresponding author

Correspondence to Mohamed Lemine Cheikh Brahim Ahmed .

Editor information

Editors and Affiliations

  1. Dept. Pharmacology Therapeutics, University of British Colombia Dept. Pharmacology Therapeutics, VANCOUVER, BC, Canada

    Ismail Laher

Section Editor information

  1. School of Nursing and Midwifery, Edith Cowan University, Joondalup, WA, Australia

    Diana Arabiat

  2. Faculty of Nursing, The University of Jordan, Amman, Jordan

    Diana Arabiat

  3. Department of Community Medicine and Public Health, Faculty of Medicine and Health Sciences, University of Aden, Aden, Yemen

    Huda Omer Basaleem

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Ahmed, M.L.C.B., El-Vally, A. (2020). Childhood Diarrhea in the Maghreb Arabic Union and Health Benefits of Rotavirus Vaccination. In: Laher, I. (eds) Handbook of Healthcare in the Arab World. Springer, Cham. https://doi.org/10.1007/978-3-319-74365-3_114-1

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  • DOI: https://doi.org/10.1007/978-3-319-74365-3_114-1

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  • Print ISBN: 978-3-319-74365-3

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