Abstract
Debated for years, the indication of whether or not to perform interval colectomy after perforated diverticular disease is again on trial, essentially due to the increasing use of laparoscopy to treat perforated colonic diverticular disease.
Most of the traditional indications for elective interval colectomy (after one acute episode for patients under 50 years of age, after two or more episodes of uncomplicated bouts of diverticulitis, or patients with complicated diverticular disease (abscess, perforation, fistula), not treated by emergency colectomy) have been recently challenged and are no longer the standard of care. According to the most recent (2014) practice parameters, neither young age nor the number of attacks of uncomplicated diverticulitis is a factor in defining the need for surgery. Patients in the so-called immunocompromised patient group, including transplant patients, patients on chronic corticosteroid therapy, or patients with chronic renal failure or collagen-vascular disease, may be candidates for early interval colectomy, while elective colectomy in anticipation of transplant remains controversial.
Routine elective surgery after nonsurgical treatment of abscesses remains debatable. As recommended by several learned societies, mesocolic abscesses of ≥5 cm or pelvic abscesses might justify surgery but the level of evidence is not strong.
For perforated diverticular disease, two randomized controlled trials comparing one-stage to two-stage treatment (initial suturing, drainage, colostomy) via laparotomy for perforated diverticular disease have published conflicting results. Since the advent of laparoscopic surgery, more and more patients are treated with simple lavage and/or drainage alone. The original tenors of this strategy advocated interval laparoscopic colectomy. While there are no clear recommendations from learned societies, the three randomized trials comparing the two strategies do not provide any definite answer as to whether interval colectomy is necessary or not, except for patients with diverticular disease complicated by hollow organ fistula or stenosis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- ACPGBI:
-
Association of Coloproctology of Great Britain and Ireland
- ASCRS:
-
American Society of Colon and Rectal Surgeons
- ASN:
-
Association of Surgeons of the Netherlands
- DSS:
-
Danish Surgical Society
- EAES:
-
European Association for Endoscopic Surgery
- WSES:
-
World Society for Emergency Surgery
References
Kohler L, Sauerland S, Neugebauer E. Diagnosis and treatment of diverticular disease: results of a consensus development conference. Surg Endosc. 1999;13:430–6.
Stollman NH, Raskin JB. Diagnosis and management of diverticular disease of the colon in adults. Ad Hoc Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol. 1999;94:3110–21.
Wong WD, Wexner SD, Lowry A, Vernava A, Burnstein M, Denstman F, Fazio V, Kerner B, Moore R, Olivier G, Peters W, Ross T, Senagore P, Simmang C. Practice parameters for the treatment of sigmoid diverticulitis. The Standards Task Force. The American Society of Colon and Rectal Surgeons. Dis Colon Rectum. 2000;43:289–97.
Janes S, Meagher A, Frizelle FA. Elective surgery after acute diverticulitis. Br J Surg. 2005;92:133–42.
Murphy SF, Waters PS, Waldron RM, Bennani F, Ryan RS, Khan W, Khan IZ, Barry K. Predictive factors for colonic resection in patients less than 49 years with symptomatic diverticular disease. Am J Surg. 2016;212(1):47–52.
Feingold D, Steele SR, Lee S, Kaiser A, Boushey R, Buie WD, Rafferty JF. Practice parameters for the treatment of sigmoid diverticulitis. Dis Colon Rectum. 2014;57:284–94.
Rafferty J, Shellito P, Hyman NH, Buie WD, The Standards Committee of The American Society of Colon and Rectal Surgeons. Practice parameters for sigmoid diverticulitis. Dis Colon Rectum. 2006;49:939–44.
Hwang SS, Cannom RR, Abbas MA, Etzioni D. Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: a systematic review. Dis Colon Rectum. 2010;53:1699–707.
Klarenbeek BR, Samuels M, van der Wal MA, van der Peet DL, Meijerink WJ, Cuesta MA. Indications for elective sigmoid resection in diverticular disease. Ann Surg. 2010;251:670–4.
Chapman J, Davies M, Wolff B, et al. Complicated diverticulitis: is it time to rethink the rules? Ann Surg. 2005;242:576–81.
Shaikh S, Krukowski ZH. Outcome of a conservative policy for managing acute sigmoid diverticulitis. Br J Surg. 2007;94:876–9.
Binda GA, Arezzo A, Serventi A, Italian Study Group on Complicated Diverticulosis (GISDIC), et al. Multicentre observational study of the natural history of left-sided acute diverticulitis. Br J Surg. 2012;99:276–85.
Ritz JP, Lehmann KS, Frericks B, Stroux A, Buhr HJ, Holmer C. Outcome of patients with acute sigmoid diverticulitis: multivariate analysis of risk factors for free perforation. Surgery. 2011;149:606–13.
Salem L, Veenstra DL, Sullivan SD, Flum DR. The timing of elective colectomy in diverticulitis: a decision analysis. J Am Coll Surg. 2004;199:904–12.
Salem TA, Molloy RG, O’Dwyer PJ. Prospective, five-year follow-up study of patients with symptomatic uncomplicated diverticular disease. Dis Colon Rectum. 2007;50:1460–4.
Kaiser AM, Jiang JK, Lake JP, et al. The management of complicated diverticulitis and the role of computed tomography. Am J Gastroenterol. 2005;100:910–7.
Ambrosetti P, Chautems R, Soravia C, Peiris-Waser N, Terrier F. Long-term outcome of mesocolic and pelvic diverticular abscesses of the left colon: a prospective study of 73 cases. Dis Colon Rectum. 2005;48:787–91.
Tursi A, Papa A, Danese S. Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon. Aliment Pharmacol Ther. 2015;42:664–84.
Rose J, Parina RP, Faiz O, Chang DC, Talamini MA. Long-term outcomes after initial presentation of diverticulitis. Ann Surg. 2015;262(6):1046–53.
Li D, Baxter NN, McLeod RS, Moineddin R, Nathens AB. The decline of elective colectomy following diverticulitis: a population-based analysis. Dis Colon Rectum. 2016;59:332–9.
O’Sullivan GC, Murphy D, O’Brien MG, Ireland A. Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. Am J Surg. 1996;171:432–4.
Myers E, Hurley M, O’Sullivan GC, Kavanagh D, Wilson I, Winter DC. Laparoscopic peritoneal lavage for generalized peritonitis due to perforated diverticulitis. Br J Surg. 2008;95:97–101.
Kronborg O. Treatment of perforated sigmoid diverticulitis: a prospective randomized trial. Br J Surg. 1993;80:505–7.
Zeitoun G, Laurent A, Rouffet F, Hay JM, Fingerhut A, Paquet JC, Peillon C. Multicentre randomized clinical trial of primary vs. secondary sigmoid resection in generalized peritonitis complicating sigmoid diverticulitis. Br J Surg. 2000;87:1366–74.
Devaraj B, Liu W, Tatum J, Cologne K, Kaiser AM. Medically treated diverticular abscess associated with high risk of recurrence and disease complications. Dis Colon Rectum. 2016;59:208–15.
Faranda C, Barrat C, Catheline JM, Champault GG. Two-stage laparoscopic management of generalised peritonitis due to perforated sigmoid diverticula: eighteen cases. Surg Laparosc Endosc Percutan Tech. 2000;10(3):135–8.
Taylor CJ, Layani L, Ghusin MA, White SI. Perforated diverticulitis managed by laparoscopic lavage. ANZ J Surg. 2006;76:962–5.
Vennix S, Morton DG, Hahnloser D, Lange JF, Bemelman WA, Research Committee of the European Society of Coloproctocology. Systematic review of evidence and consensus on diverticulitis: an analysis of national and international guidelines. Color Dis. 2014;16:866–78.
Vennix S, Musters GD, Mulder IM, Swank HA, Consten EC, Belgers EH, van Geloven AA, Gerhards MF, Govaert MJ, van Grevenstein WM, Hoofwijk AG, Kruyt PM, Nienhuijs SW, Boermeester MA, Vermeulen J, van Dieren S, Lange JF, Bemelman WA, Ladies Trial Collaborators. Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet. 2015;386:1269–77.
Angenete E, Thornell A, Burcharth J, Pommergaard H-C, Skullman S, Bisgaard T, Jess P, Lackberg Z, Matthiessen P, Heath J, Rosenberg J, Haglind E. Laparoscopic lavage is feasible and safe for the treatment of perforated diverticulitis with purulent peritonitis. The first results from the randomized controlled trial DILALA. Ann Surg. 2016;263:117–22.
Schultz JK, Yaqub S, Wallon C, Blecic L, Forsmo HM, Folkesson J, Buchwald P, Korner H, Dahl FA, Oresland T, SCANDIV Study Group. Laparoscopic lavage vs primary resection for acute perforated diverticulitis the SCANDIV randomized clinical trial. JAMA. 2015;314(13):1364–75.
Afshar S, Kurer MA. Laparoscopic peritoneal lavage for perforated sigmoid diverticulitis. Color Dis. 2011;14:135–42.
Cuomo R, Barbara G, Pace F, Annese V, Bassotti G, Binda GA, Casetti T, Colecchia A, Festi D, Fiocca R, Laghi A, Maconi G, Nascimbeni R, Scarpignato C, Villanacci V, Annibale B. Italian consensus conference for colonic diverticulosis and diverticular disease. United European Gastroenterol J. 2014;2(5):413–42.
Andersen JC, Bundgaard L, Elbrond H, et al. Danish national guidelines for treatment of diverticular disease. Dan Med J. 2012;59:C4453.
Andeweg CS, Mulder IM, Felt-Bersma RJ, et al. Guidelines of diagnostics and treatment of acute left-sided colonic diverticulitis. Dig Surg. 2013;30:278–92.
Agresta F, Ansaloni L, Baiocchi GL, et al. Laparoscopic approach to acute abdomen from the Consensus Development Conference of the Societa Italiana di Chirurgia Endoscopica e nuove tecnologie (SICE), Associazione Chirurghi Ospedalieri Italiani (ACOI), Societa Italiana di Chirurgia (SIC), Societa Italiana di Chirurgia d’Urgenza e del Trauma (SICUT), Societa Italiana di Chirurgia nell’Ospedalita Priv ata (SICOP), and the European Association for Endoscopic Surgery (EAES). Surg Endosc. 2012;26:2134–64.
Solkar MH, Forshaw MJ, Sankararajah D, Stewart M, Parker MC. Colovesical fistula–is a surgical approach always justified? Color Dis. 2005;7:467–71.
Sallinen V, Mentula P, Leppaniemi A. Risk of colon cancer after computed tomography-diagnosed acute diverticulitis: is routine colonoscopy necessary? Surg Endosc. 2014;28:961–6.
Lau KC, Spilsbury K, Farooque Y, Kariyawasam SB, Owen RG, Wallace Afshar S, Kurer MA. Laparoscopic peritoneal lavage for perforated sigmoid diverticulitis. Color Dis. 2011;14:135–42.
Sharma PV, Eglinton T, Hider P, Frizelle F. Systematic review and meta-analysis of the role of routine colonic evaluation after radiologically confirmed acute diverticulitis. Ann Surg. 2014;259(2):263–72.
Fozard JB, Armitage NC, Schofield JB, Jones OM. ACPGBI position statement on elective resection for diverticulitis. Color Dis. 2011;13(Suppl 3):1–11.
van de Wall BJ, Draaisma WA, van Iersel JJ, Consten EC, Wiezer MJ, Broeders IA. Elective resection for ongoing diverticular disease significantly improves quality of life. Dig Surg. 2013;30:190–7.
Mäkelä JT, Kiviniemi HO, Laitinen ST. Elective surgery for recurrent diverticulitis. Hepato-Gastroenterology. 2007;54:1412–6.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this chapter
Cite this chapter
Fingerhut, A., Boni, L., Justin, V., Uranues, S. (2018). Perforated Diverticulitis: When Is Interval Resection Really Indicated?. In: Schlachta, C., Sylla, P. (eds) Current Common Dilemmas in Colorectal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-70117-2_13
Download citation
DOI: https://doi.org/10.1007/978-3-319-70117-2_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-70116-5
Online ISBN: 978-3-319-70117-2
eBook Packages: MedicineMedicine (R0)