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Pulmonary Complications of Neuromuscular and Other Genetic Disorders

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Pulmonary Complications of Non-Pulmonary Pediatric Disorders

Part of the book series: Respiratory Medicine ((RM))

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Abstract

The respiratory system is a complex system involving different organs which interact with each other to provide an efficient breathing, adapted to growth and physiological situations such as rest, sleep, and exercise. Prominent among them are the nervous (especially the central nervous system) and the musculoskeletal systems whose malfunction can have profound effects on breathing even when the respiratory system per se is normal and healthy. The following chapter reviews the physiology of breathing with emphasis on the changes that occur during exercise and sleep. In addition it reviews the effects of the failure of the “respiratory pump” due to the various neuromuscular and skeletal disorders as well as the effects of specific genetic disorders on breathing.

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Author information

Authors and Affiliations

  1. Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker Enfants-Malades, Paris, France

    Alessandro Amaddeo M.D., Sonia Khirani Ph.D. & Brigitte Fauroux MD, PhD

  2. Paris Descartes Faculty, Paris, France

    Alessandro Amaddeo M.D. & Brigitte Fauroux MD, PhD

  3. Research Unit Inserm U 955, Team 13, Créteil, France

    Alessandro Amaddeo M.D. & Brigitte Fauroux MD, PhD

  4. ASV Santé, Gennevilliers, France

    Sonia Khirani Ph.D.

Authors
  1. Alessandro Amaddeo M.D.
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  2. Sonia Khirani Ph.D.
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  3. Brigitte Fauroux MD, PhD
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Corresponding author

Correspondence to Brigitte Fauroux MD, PhD .

Editor information

Editors and Affiliations

  1. George Washington University School of Medicine, Children’s National Medical Center, Washington, DC, USA

    Anastassios C. Koumbourlis

  2. Ann & Robert H. Lurie Children’s Hospital, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA

    Mary A. Nevin

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Amaddeo, A., Khirani, S., Fauroux, B. (2018). Pulmonary Complications of Neuromuscular and Other Genetic Disorders. In: Koumbourlis, A., Nevin, M. (eds) Pulmonary Complications of Non-Pulmonary Pediatric Disorders. Respiratory Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-69620-1_7

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  • DOI: https://doi.org/10.1007/978-3-319-69620-1_7

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-69619-5

  • Online ISBN: 978-3-319-69620-1

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