Abstract
There is increasing evidence to support the view that angiogenesis and inflammation are mutually dependent (Fig. 6.1) (Mueller 2008). During inflammatory reactions, immune cells synthesize and secrete pro-angiogenic factors that promote neovascularization. Among the cytokines, IL-6, TNF-α and CXCR2 chemokine receptor and its ligand promote angiogenesis in tumor microenvironment.
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References
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Ribatti, D. (2017). Inflammation and Angiogenesis. In: Inflammation and Angiogenesis. Springer, Cham. https://doi.org/10.1007/978-3-319-68448-2_6
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DOI: https://doi.org/10.1007/978-3-319-68448-2_6
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