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Total Body Irradiation in Stem Cell Transplant

  • Living reference work entry
  • First Online:
Contemporary Bone Marrow Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

Abstract

Total body irradiation (TBI) is a radiation therapy technique that is designed to deliver radiation to the entire body and has been used to treat a variety of malignant and benign disorders. Total body irradiation sequenced with chemotherapy remains a significant part of hematopoietic stem cell transplantation (HSCT). Better understanding of biological effects of ionizing radiation, improved dosimetry, and enhanced knowledge of radiation therapy-chemotherapy and/or biological interactions has led to refinement in the technique and the use of TBI. This chapter comprehensively addresses TBI in allogeneic stem cell transplantation.

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Authors and Affiliations

  1. Department of Radiation Oncology, Tata Medical Center, Kolkata, India

    Rimpa Achari, Abhijit Das & Anurupa Mahata

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  1. Rimpa Achari
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  2. Abhijit Das
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  3. Anurupa Mahata
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Correspondence to Rimpa Achari .

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Editors and Affiliations

  1. Tata Medical Center, Kolkata, West Bengal, India

    Mammen Chandy

  2. CLINICAL HAEMATOLOGY and HCT, Tata Medical Center, Kolkata, West Bengal, India

    Vivek S Radhakrishnan

  3. Oncology Centre of Excellence, Tata Medical Center, Kolkata, West Bengal, India

    Reghu Sukumaran

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  1. Tata Medical Center, Kolkata, India

    Vivek Radhakrishnan

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Achari, R., Das, A., Mahata, A. (2020). Total Body Irradiation in Stem Cell Transplant. In: Chandy, M., Radhakrishnan, V., Sukumaran, R. (eds) Contemporary Bone Marrow Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-64938-2_23-1

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  • DOI: https://doi.org/10.1007/978-3-319-64938-2_23-1

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