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New Developments and Treatment Options of Cellulitis in the Hospital

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Clinical Approaches to Hospital Medicine

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Abstract

Cellulitis is a common problem encountered in both outpatient and inpatient medicine and is a large contributor to healthcare expenditure. The best way to cut down on spending due to lengthy hospital stays and high readmission rates is to improve diagnostic accuracy, prescribe effective antibiotics, and address underlying risk factors for development of cellulitis. Patients with risk factors such as stasis dermatitis should be regularly checked for the development of infection. Current antibiotic choice for cellulitis infections is guided by the commonly suspected pathogens: Staphylococcus aureus and Group A Streptococcus. Patients who do not respond to outpatient therapy or who meet SIRS criteria should be considered for inpatient therapy. New emerging treatment options have become available that have proven to be very effective. This ranges from a once weekly antibiotic, Dalbavancin, to one that can effectively eradicate the infection with one dose; Oritavancin. These new antibiotic choices can improve patient adherence to treatment and help reduce antibiotic resistant infections.

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References

  1. Stevens DL, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59(2):e10–52.

    Article  PubMed  Google Scholar 

  2. Eljaaly K, et al. Antibiotic dosing discrepancies in the 2014 skin and soft tissue infections guidelines. Clin Infect Dis. 2015;60(11):1731–2.

    Article  PubMed  Google Scholar 

  3. Wolff K, Johnson RA, Saavedra AP. Fitzpatricks color atlas and synopsis of clinical dermatology. 7th ed. New York: McGraw-Hill; 2013. p. 531–41.

    Google Scholar 

  4. Raff AB, Kroshinsky D. Cellulitis: a review. JAMA. 2016;316(3):325–37.

    Google Scholar 

  5. Moran GJ, et al. Acute bacterial skin infections: developments since the 2005 Infectious Diseases Society of America (IDSA) guidelines. J Emerg Med. 44(6):e397–412.

    Google Scholar 

  6. Miller LG, et al. Clindamycin versus trimethoprim-sulfamethoxazole for uncomplicated skin infections. NEJM. 2015;372(12):1093–103.

    Google Scholar 

  7. Chen KC, et al. An overview of point-of-care ultrasound for soft tissue and musculoskeletal applications in the emergency department. Journal of intensive care. 2016;4:55.

    Google Scholar 

  8. Ibrahim F, Khan T, Pujalte GG. Bacterial skin infections. Prim Care. 2015;42(4):485–99. doi:10.1016/j.pop.2015.08.001. Review.

  9. Corey GR, et al. Single-dose oritavancin in the treatment of acute bacterial skin infections. N Engl J Med. 2014;370(23):2180–90.

    Google Scholar 

  10. Dryden MS. Complicated skin and soft tissue infection. J Antimicrob Chemother. 2010;65(Suppl 3):iii35–44.

    Google Scholar 

  11. Creech CB, Al-Zubeidi DN, Fritz SA. Prevention of recurrent staphylococcal skin infections. Infect Dis Clin N Am. 2015;29(3):429–64.

    Google Scholar 

  12. Yue J, Dong B R, Yang M, Chen X, Wu T. & Liu G. J. Linezolid versus vancomycin for skin and soft tissue infections. Evidence‐Based Child Health: A Cochrane Review Journal. 2014;9(1):103–66.

    Google Scholar 

  13. Prokocimer P, De Anda C, Fang E, Mehra P, & Das A. Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial. Jama. 2013;309(6):559–69.

    Google Scholar 

  14. Pulia, M. S., Calderone, M. R., Meister, J. R., Santistevan, J., & May, L. Update on management of skin and soft tissue infections in the emergency department. Current infectious disease reports. 2014;16(9):418.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Ochsner Health Center, New Orleans, LA, USA

    Stephanie Bender

  2. Ochsner Clinical School, The University of Queensland, New Orleans, LA, USA

    Katherine Oakden

Authors
  1. Stephanie Bender
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  2. Katherine Oakden
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Correspondence to Stephanie Bender .

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Editors and Affiliations

  1. Medical Director of Community Affairs and Health Policy, Ochsner Health Systems, New Orleans, Louisiana, USA

    Kevin Conrad

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Bender, S., Oakden, K. (2018). New Developments and Treatment Options of Cellulitis in the Hospital. In: Conrad, K. (eds) Clinical Approaches to Hospital Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-64774-6_6

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  • DOI: https://doi.org/10.1007/978-3-319-64774-6_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-64773-9

  • Online ISBN: 978-3-319-64774-6

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