Skip to main content
SpringerLink
Log in

Polycythemia Vera

  • Chapter
  • First Online:
Consults in Obstetric Anesthesiology

  • 131 Accesses

Abstract

Polycythemia vera is a myeloproliferative neoplasm resulting in unregulated erythropoiesis. The overall incidence is relatively low in the child-bearing age population, with fewer than 50 cases reported in pregnant women. Mainstays of treatment include reduction of the hemoglobin and mitigation of the increased risk of thrombosis. Live birth rates in patients with polycythemia vera are low but can potentially be improved with treatment. Anesthetic management centers around venous thromboembolism prophylaxis. Common anesthetic agents are believed to be safe in patients with polycythemia vera. Neuraxial anesthesia is likely safe as long as the platelet and neutrophil counts are adequate and the patient is not currently receiving anticoagulation.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Tefferi A, Thiele J, Orazi A, et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel. Blood. 2007;110:1092–7.

    Article  CAS  Google Scholar 

  2. Johansson P. Epidemiology of the myeloproliferative disorders polycythemia vera and essential thrombocythemia. Semin Thromb Hemost. 2006;32(3):171.

    Article  Google Scholar 

  3. Aggarwal N, Chopra S, Suri V, Sikka P, Goundan A, Malhotra P. Polycythemia vera and pregnancy: experience of four pregnancies in a single patient. Arch Gynecol Obstet. 2011;283:393–5.

    Article  Google Scholar 

  4. Vannucchi AM. How I treat polycythemia vera. Blood. 2014;124:3212–20.

    Article  CAS  Google Scholar 

  5. Tiede A, Rand JH, Budde U, Ganser A, Federici AB. How I treat the acquired von Willebrand syndrome. Blood. 2011;117:6777–85.

    Article  CAS  Google Scholar 

  6. Robinson S, Bewley S, Hunt BJ, Radia DH, Harrison CN. The management and outcome of 18 pregnancies in women with polycythemia vera. Haematologica. 2005;90:1477–83.

    PubMed  Google Scholar 

  7. Griesshammer M, Struve S, Harrison CM. Essential thrombocythemia/polycythemia vera and pregnancy: the need for an observational study in Europe. Semin Thromb Hemost. 2006;32:422–9.

    Article  Google Scholar 

  8. Toogeh G, Ferdowsi S, Naadali F, et al. Concomitant presence of JAK2 V617F mutation and BCR-ABL translocation in a pregnant woman with polycythemia vera. Med Oncol. 2011;28:1555–8.

    Article  CAS  Google Scholar 

  9. Sethi S, Kumari K. Anesthetic management of a patient with polycythemia vera for nephrectomy. Int J Anesthesiol Res. 2015;3:147–9.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Anesthesiology, University of Cincinnati Medical Center, Cincinnati, OH, USA

    Andrea Girnius M.D.

  2. Division Director Obstetric Anesthesia, University of Cincinnati Medical Center and West Chester Hospital, Cincinnati, OH, USA

    Lesley Gilbertson M.D.

Authors
  1. Andrea Girnius M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lesley Gilbertson M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Andrea Girnius M.D. .

Editor information

Editors and Affiliations

  1. Associate Professor, Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA

    Suzanne K. W. Mankowitz

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Girnius, A., Gilbertson, L. (2018). Polycythemia Vera. In: Mankowitz, S. (eds) Consults in Obstetric Anesthesiology. Springer, Cham. https://doi.org/10.1007/978-3-319-59680-8_125

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-59680-8_125

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-59679-2

  • Online ISBN: 978-3-319-59680-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation