Abstract
Central venous pressure influences FFR measurements because it decreases the perfusion gradient distal to the stenosis proportionally more than it does proximal to it. The impact of central venous pressure is minimal for normal pressure values and for FFR values away from the threshold. However, in conditions where FFR is close to 0.80 and central venous pressure is high, it might play an important role in reclassifying stenoses from not relevant to relevant.
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Reference
Toth GG, de Bruyne B, Rusinaru D, Di Gioia G, Bartunek J, Pellicano M, et al. Impact of right atrial pressure on fractional flow reserve measurements: comparison of fractional flow reserve and myocardial fractional flow reserve in 1,600 coronary stenoses. JACC Cardiovasc Interv. 2016;9:453–9.
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Gori, T. (2016). The Impact of Venous Pressure on FFR: Do Diuretics Affect FFR?. In: Gori, T., Fineschi, M. (eds) Atlas of FFR-Guided Percutaneous Coronary Interventions. Springer, Cham. https://doi.org/10.1007/978-3-319-47116-7_37
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DOI: https://doi.org/10.1007/978-3-319-47116-7_37
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