Abstract
Metabolic/endocrinological diseases of bone are a major topic in human medicine, but are not that frequent in veterinary medicine. We will focus on two major bone diseases of human medicine, namely, osteoporosis and hyperparathyroidism, and compare their expression and pathophysiology in companion animals. In humans, postmenopausal osteoporosis is the most frequent and economically most important bone disease, but interestingly has no direct equivalent in veterinary medicine. This is also due to the fact that osteoporosis is not only a matter of low bone mineral density but also of altered bone (micro)structure. Also, hypoestrogenism does not seem to be of that clinical importance in our domestic mammals. On the other hand, hyperparathyroidism, which is frequently diagnosed in humans as well, resembles a clinical problem also the veterinarian has to deal with.
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References for Further Reading
Kleerekoper M (2013) Osteoporosis overview. In: Rosen CJ, Bouillon R, Compston JE, Rosen V et al (eds) Primer on the metabolic bone diseases and disorders of mineral metabolism, 8th edn. Wiley-Blackwell, Ames, pp 345–347
McGavin MD, Zachary JF (eds) (2012) Pathologic basis of veterinary disease, 5th edn. Elsevier Mosby, St. Louis
NIH Consensus Statement (2000) Osteoporosis prevention, diagnosis, and therapy. JAMA 17:1–45
Pietschmann P, Rauner M, Sipos W, Kerschan-Schindl K (2009) Osteoporosis: an age-related and gender-specific disease – a mini-review. Gerontology 55:3–12
Potts JT, Jüppner H (2012) Disorders of the parathyroid gland and calcium homeostasis. In: Longo DL, Kasper DL, Jameson JL, Fauci AS, Hauser SL, Loscalzo J (eds) Harrison’s principles of internal medicine, vol 2, 18th edn. McGraw Hill Medical, New York, pp 3096–3120
Silverberg SJ (2013) Primary hyperparathyroidism. In: Rosen CJ, Bouillon R, Compston JE, Rosen V et al (eds) Primer on the metabolic bone diseases and disorders of mineral metabolism, 8th edn. Wiley-Blackwell, Ames, pp 543–552
Sipos W (2016) Antibodies for the Treatment of Bone Diseases: Preclinical Data. In: Pietshmann P (ed) Principles of osteoimmunology, 2nd edn. Springer, Wien/New York, pp 217–237
Symons JE, Entwistle RC, Arens AM, Garcia TC, Christiansen BA, Fyhrie DP, Stoyer SM (2012) Mechanical and morphological properties of trabecular bone samples obtained from third metacarpal bones of cadavers of horses with a bone fragility syndrome and horses unaffected by that syndrome. Am J Vet Res 73:1742–1751
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Sipos, W., Föger-Samwald, U., Pietschmann, P. (2017). Comparing Two Major Bone Pathologies in Humans and Companion Animals: Osteoporosis and Hyperparathyroidism. In: Jensen-Jarolim, E. (eds) Comparative Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-47007-8_6
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DOI: https://doi.org/10.1007/978-3-319-47007-8_6
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