Abstract
Drug delivery is attractive approach for medicine field, as more potent and specific drugs are being developed. With the integration of nanotechnology, so-called smart drug-delivery systems integrate biosensing functionalities which sustain independently in vivo reaction control that resulting in part unique features of the term Nanomedicine. Nanotechnology is one of the very frontiers of science today. Current polymeric research is dominantly participating in the advancement of nanotechnology by offering the controlled release of therapeutic agents in constant doses over prolong periods, cyclic dosage, and tunable release of both hydrophilic and hydrophobic drugs. Many biomaterials can be used to this end, offering extensive chemical diversity and the potential for further modification using nanoparticles. Conventional methods of drug delivery present several disadvantages, mainly due to off-target effects that may originate severe side and toxic effect to healthy tissues. New drug delivery systems based on nanoscale devices showing new and improved properties and developed as promising solutions for achieving desirable therapeutic efficacy. Here, we provide a broad overview of novel nanoparticle based drug delivery systems, covering its innovations, applications and commercialization systems using both natural and synthetic polymers.
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Bhatia, S. (2016). Nanotechnology and Its Drug Delivery Applications. In: Natural Polymer Drug Delivery Systems. Springer, Cham. https://doi.org/10.1007/978-3-319-41129-3_1
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