Skip to main content

Arrhythmias and Electrolyte Imbalances as Consequences of Cancer

  • Chapter
  • First Online:
Manual of Cardio-oncology

Abstract

Both arrhythmias and electrolyte imbalances are rather frequent consequences of cancer itself and of cancer treatments (and their side effects). Arrhythmias may be also a consequence of electrolyte imbalance.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. O’Neal WT, Lakoski SG, Qureshi W, et al. Relation between cancer and atrial fibrillation (from the REasons for Geographic And Racial Differences in Stroke Study). Am J Cardiol. 2015;115:1090–4.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Erichsen R, Christiansen CF, Mehnert F, et al. Colorectal cancer and risk of atrial fibrillation and flutter: a population-based case–control study. Intern Emerg Med. 2012;7:431–8.

    Article  PubMed  Google Scholar 

  3. Guzzetti S, Costantino G, Sada S, Fundarò C. Colorectal cancer and atrial fibrillation: a case–control study. Am J Med. 2002;112:587–8.

    Article  PubMed  Google Scholar 

  4. Onaitis M, D’Amico T, Zhao Y, et al. Risk factors for atrial fibrillation after lung cancer surgery: analysis of the society of thoracic surgeons general thoracic surgery database. Ann Thorac Surg. 2010;90:368–74.

    Article  PubMed  Google Scholar 

  5. Ostan R, Lanzarini C, Pini E, et al. Inflammaging and cancer: a challenge for the Mediterranean diet. Nutrients. 2015;7:2589–621.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Guo Y, Lip GY, Apostolakis S. Inflammation in atrial fibrillation. J Am Coll Cardiol. 2012;60:2263–70. Review.

    Article  CAS  PubMed  Google Scholar 

  7. Guzzetti S, Costantino G, Fundarò C. Systemic inflammation, atrial fibrillation, and cancer. Circulation. 2002;106(9):e40. author reply e40.

    Article  PubMed  Google Scholar 

  8. Erichsen R, Christiansen CF, Frøslev T, et al. Intravenous bisphosphonate therapy and atrial fibrillation/flutter risk in cancer patients: a nationwide cohort study. Br J Cancer. 2011;105:881–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Imperatori A, Mariscalco G, Riganti G, et al. Atrial fibrillation after pulmonary lobectomy for lung cancer affects long-term survival in a prospective single-center study. J Cardiothorac Surg. 2012;7:4.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Cardinale D, Sandri MT, Colombo A, et al. Prevention of atrial fibrillation in high-risk patients undergoing lung cancer surgery: the PRESAGE trial. Ann Surg. 2016;264(2):244–51.

    Google Scholar 

  11. Zhang L, Gao S. Systematic review and meta-analysis of atrial fibrillation prophylaxis following lung surgery. J Cardiovasc Pharmacol. 2016;67(4):351–7.

    Google Scholar 

  12. January CT, Wann LS, Alpert JS, American College of Cardiology/American Heart Association Task Force on Practice Guidelines, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1–76.

    Article  PubMed  Google Scholar 

  13. Wellens HJ, Schwartz PJ, Lindemans FW, et al. Risk stratification for sudden cardiac death: current status and challenges for the future. Eur Heart J. 2014;35:1642–51.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Melichar B, Králíčková P, Hyšpler R, et al. Hypomagnesaemia in patients with metastatic colorectal carcinoma treated with cetuximab. Hepatogastroenterology. 2012;59:366–71.

    CAS  PubMed  Google Scholar 

  15. Dutta S, Horgan PG, McMillan DC. POSSUM and its related models as predictors of postoperative mortality and morbidity in patients undergoing surgery for gastro-oesophageal cancer: a systematic review. World J Surg. 2010;34:2076–82.

    Article  PubMed  Google Scholar 

  16. Filip B, Scarpa M, Cavallin F, et al. Postoperative outcome after oesophagectomy for cancer: nutritional status is the missing ring in the current prognostic scores. Eur J Surg Oncol. 2015;41:787–94.

    Article  CAS  PubMed  Google Scholar 

  17. Wahr JA, Parks R, Boisvert D, et al. Preoperative serum potassium levels and perioperative outcomes in cardiac surgery patients. JAMA. 1999;281:2203–10.

    Article  CAS  PubMed  Google Scholar 

  18. DeCarolis DD, Kim GM, Rector TS, Ishani A. Comparative dose response using the intravenous versus enteral route of administration for potassium replenishment. Intensive Crit Care Nurs. 2016;36:17–23.

    Google Scholar 

  19. Vanden Hoek TL, Morrison LJ, Shuster M, et al. Part 12: cardiac arrest in special situations: 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2010;122:S829–61.

    Article  PubMed  Google Scholar 

  20. Soar J, Deakin CD, Nolan JP, European Resuscitation Council, et al. European Resuscitation Council guidelines for resuscitation 2005. Section 7. Cardiac arrest in special circumstances. Resuscitation. 2005;67 Suppl 1:S135–70. Review.

    Article  PubMed  Google Scholar 

  21. Santarpia L, Koch CA, Sarlis NJ. Hypercalcemia in cancer patients: pathobiology and management. Horm Metab Res. 2010;42:153–64.

    Article  CAS  PubMed  Google Scholar 

  22. Maier JD, Levine SN. Hypercalcemia in the intensive care unit: a review of pathophysiology, diagnosis, and modern therapy. J Intensive Care Med. 2015;30:235–52.

    Article  PubMed  Google Scholar 

  23. Le Grand SB. Modern management of malignant hypercalcemia. Am J Hosp Palliat Care. 2011;28:515–7.

    Article  Google Scholar 

  24. Sabry NA, Habib EE. Zoledronic acid and clodronate in the treatment of malignant bone metastases with hypercalcaemia; efficacy and safety comparative study. Med Oncol. 2011;28:584–90.

    Article  CAS  PubMed  Google Scholar 

  25. Overgaard-Steensen C, Ring T. Clinical review: practical approach to hyponatraemia and hypernatraemia in critically ill patients. Crit Care. 2013;17:206.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Nagler EV, Vanmassenhove J, Van der Veer SN, Nistor I, Van Biesen W, Webster AC, Vanholder R. Diagnosis and treatment of hyponatremia: a systematic review of clinical practice guidelines and consensus statements. BMC Med. 2014;12:231.

    Article  Google Scholar 

  27. Adrogue HJ, Madias NE. Primary care: hyponatremia. New Engl J Med. 2000;342:1581–9.

    Article  CAS  PubMed  Google Scholar 

  28. Adrogue HJ, Madias NE. Primary care: hypernatremia. New Engl J Med. 2000;342:1493–9.

    Article  CAS  PubMed  Google Scholar 

  29. Ye Z, Palazzo JP, Lin L, et al. Postoperative hyperphosphatemia significantly associates with adverse survival in colorectal cancer patients. J Gastroenterol Hepatol. 2013;28:1469–75.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Mughal T, Ejaz AA, Foringer JR, Coiffier B. An integrated clinical approach for the identification, prevention, and treatment of tumor lysis syndrome. Cancer Treat Rev. 2010;36:164–76.

    Article  PubMed  Google Scholar 

  31. Mika D, Ahmad S, Guruvayoorappan C. Tumour lysis syndrome: implications for cancer therapy. Asian Pac J Cancer Prev. 2012;13:3555–60. Review.

    Article  PubMed  Google Scholar 

  32. Akoz AG, Yildirim N, Engin H, et al. An unusual case of spontaneous acute tumor lysis syndrome associated with acute lymphoblastic leukemia: a case report and review of the literature. Acta Oncol. 2007;46:1190–2. Review.

    Article  PubMed  Google Scholar 

  33. Rasool M, Malik A, Qureshi MS, et al. Development of tumor lysis syndrome (TLS): a potential risk factor in cancer patients receiving anticancer therapy. Bioinformation. 2014;10:703–7.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Darmon M, Vincent F, Camous L, Groupe de Recherche en Réanimation Respiratoire et Onco-Hématologique (GRRR-OH), et al. Tumour lysis syndrome and acute kidney injury in high-risk haematology patients in the rasburicase era. A prospective multicentre study from the Groupe de Recherche en Réanimation Respiratoire et Onco-Hématologique. Br J Haematol. 2013;162:489–97.

    Article  CAS  PubMed  Google Scholar 

  35. Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol. 2004;127:3–11. Review.

    Article  PubMed  Google Scholar 

  36. Howard SC, Jones DP, Pui CH. The tumor lysis syndrome. N Engl J Med. 2011;364:1844–54. Review.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Montesinos P, Lorenzo I, Martín G, et al. Tumor lysis syndrome in patients with acute myeloid leukemia: identification of risk factors and development of a predictive model. Haematologica. 2008;93:67–74.

    Article  CAS  PubMed  Google Scholar 

  38. Weeks AC, Kimple ME. Spontaneous tumor lysis syndrome: a case report and critical evaluation of current diagnostic criteria and optimal treatment regimens. J Investig Med High Impact Case Rep. 2015;3:2324709615603199.

    PubMed  PubMed Central  Google Scholar 

  39. Wilson FP, Berns JS. Tumor lysis syndrome: new challenges and recent advances. Adv Chronic Kidney Dis. 2014;21:18–26.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Malaguarnera G, Giordano M, Malaguarnera M. Rasburicase for the treatment of tumor lysis in hematological malignancies. Expert Rev Hematol. 2012;5:27–38.

    Article  CAS  PubMed  Google Scholar 

  41. Browning LA, Kruse JA. Hemolysis and methemoglobinemia secondary to rasburicase administration. Ann Pharmacother. 2005;39(11):1932–5.

    Article  PubMed  Google Scholar 

  42. Cheuk DK, Chiang AK, Chan GC, Ha SY. Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer. Cochrane Database Syst Rev. 2014;8:CD006945.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Iris Parrini .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Maurea, N., Parrini, I., Lestuzzi, C. (2017). Arrhythmias and Electrolyte Imbalances as Consequences of Cancer. In: Lestuzzi, C., Oliva, S., Ferraù, F. (eds) Manual of Cardio-oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-40236-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-40236-9_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-40234-5

  • Online ISBN: 978-3-319-40236-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics