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Venereal Disease II: Chlamydia trachomatis Infection, Gonorrhoea

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Antibiotic and Antifungal Therapies in Dermatology

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Abstract

Chlamydia trachomatis infection and gonorrhoea are the first two most reported STIs, and often the patients are infected with the both pathogenic agents. Clinical diagnosis may be hampered when the infections run asymptomatic or oligosymptomatic courses. Untreated infections can result in local, regional or systemic complications with severe outcome (e.g. infertility). Classic laboratory investigations such as cultures, microscopy and immunostaining have been widely replaced in industrialized countries by molecular diagnostic methods. The treatment is based on guidelines that need constant updates due to the rapid development of resistance of C. trachomatis and N. gonorrhoeae to antibiotic treatments. C. trachomatis treatment is based on azithromycin or doxycycline. N. gonorrhoeae is efficiently destroyed by combined therapy: ceftriaxone and azithromycin.

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Author information

Authors and Affiliations

  1. Dermatology 2, Colentina Clinical Hospital, Carol Davila University of Medicine and Pharmacy, Sos. Stefan cel Mare nr. 19-21, 020125, Bucharest, Romania

    George-Sorin Tiplica

  2. Research Division of Skin Biology and Pathobiology, Department of Dermatology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria

    Erwin Tschachler

Authors
  1. George-Sorin Tiplica
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  2. Erwin Tschachler
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Correspondence to George-Sorin Tiplica .

Editor information

Editors and Affiliations

  1. Department of Dermatology and Venereology, University of Iceland,(Hudlaeknastodin Dermatology Clinic), Kopavogur, Iceland

    Jón Hjaltalín Ólafsson

  2. Cutaneous Infection Clinic, Dermatology, Kings College Hospital NHS Trust, London, United Kingdom

    Roderick James Hay

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Tiplica, GS., Tschachler, E. (2016). Venereal Disease II: Chlamydia trachomatis Infection, Gonorrhoea. In: Ólafsson, J., Hay, R. (eds) Antibiotic and Antifungal Therapies in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-319-39424-4_5

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  • DOI: https://doi.org/10.1007/978-3-319-39424-4_5

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-39424-4

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