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Percutaneous Vertebral Augmentation: Vertebroplasty and Kyphoplasty

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Minimally Invasive Surgery in Orthopedics

Abstract

Vertebroplasty and balloon kyphoplasty are two percutaneous surgical options for the treatment of osteoporotic vertebral compression fractures (VCF) that have become increasingly utilized since their development in the mid 1980s. These well-described techniques can also address VCF caused by metastatic lesions, multiple myeloma, and hemangiomas. Physicians from several disciplines including neurosurgery, orthopedic surgery, and radiology now perform vertebroplasty and balloon kyphoplasty as a routine part of their practice. The surgical goals of vertebroplasty are to stabilize the fractured vertebral body and provide relief from pain. Pain is thought to be alleviated from bonding and strengthening the fractured vertebral body, as well as from the thermal reaction that occurs during the curing of the polymethylmethacrylate (PMMA) cement. Balloon kyphoplasty has similar goals but also aims at partially correcting the deformity by restoring the vertebral body height. However, controversy does exist over whether the pain is relieved from fracture stabilization, the PMMA thermal reaction, or from the restoration of vertebral height. Recent developments have included using an arc osteotome, which is placed through a percutaneous transpedicular approach, for cavity creation prior to filling the defect with PMMA cement. This chapter summarizes the indications, techniques, and complications for both the vertebroplasty with and without cavity creation.

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References

  1. Galibert P, Deramond H, Rosat P, Le Gars D. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie. 1987;33(2):166–8.

    CAS  PubMed  Google Scholar 

  2. Chen JF, Wu CT, Lee ST. Percutaneous vertebroplasty for the treatment of burst fractures. Case report. J Neurosurg Spine. 2004;1(2):228–31.

    Article  PubMed  Google Scholar 

  3. Ray NF, Chan JK, Thamer M, Melton III LJ. Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation. J Bone Miner Res. 1997;12(1):24–35.

    Article  CAS  PubMed  Google Scholar 

  4. Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR. Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group. Arch Intern Med. 1999;159(11):1215–20.

    Article  CAS  PubMed  Google Scholar 

  5. Cooper C, Atkinson EJ, O’Fallon WM, Melton III LJ. Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985–1989. J Bone Miner Res. 1992;7(2):221–7.

    Article  CAS  PubMed  Google Scholar 

  6. Lyles KW. Management of patients with vertebral compression fractures. Pharmacotherapy. 1999;19(1 Pt 2):21S–4.

    Article  CAS  PubMed  Google Scholar 

  7. Melton III LJ. Epidemiology worldwide. Endocrinol Metab Clin North Am. 2003;32(1):1–13. v.

    Article  PubMed  Google Scholar 

  8. Olszynski WP, Shawn Davison K, Adachi JD, et al. Osteoporosis in men: epidemiology, diagnosis, prevention, and treatment. Clin Ther. 2004;26(1):15–28.

    Article  PubMed  Google Scholar 

  9. Rao RD, Singrakhia MD. Painful osteoporotic vertebral fracture. Pathogenesis, evaluation, and roles of vertebroplasty and kyphoplasty in its management. J Bone Joint Surg Am. 2003;85-A(10):2010–22.

    PubMed  Google Scholar 

  10. Fourney DR, Schomer DF, Nader R, et al. Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients. J Neurosurg. 2003;98 Suppl 1:21–30.

    PubMed  Google Scholar 

  11. Wise JJ, Fischgrund JS, Herkowitz HN, Montgomery D, Kurz LT. Complication, survival rates, and risk factors of surgery for metastatic disease of the spine. Spine. 1999;24(18):1943–51.

    Article  CAS  PubMed  Google Scholar 

  12. Greenlee RT, Murray T, Bolden S, Wingo PA. Cancer statistics, 2000. CA Cancer J Clin. 2000;50(1):7–33.

    Article  CAS  PubMed  Google Scholar 

  13. Aebi M. Spinal metastasis in the elderly. Eur Spine J. 2003;12 Suppl 2:S202–13.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Burton AW, Reddy SK, Shah HN, Tremont-Lukats I, Mendel E. Percutaneous vertebroplasty – a technique to treat refractory spinal pain in the setting of advanced metastatic cancer: a case series. J Pain Symptom Manage. 2005;30(1):87–95.

    Article  PubMed  Google Scholar 

  15. Chow E, Holden L, Danjoux C, et al. Successful salvage using percutaneous vertebroplasty in cancer patients with painful spinal metastases or osteoporotic compression fractures. Radiother Oncol. 2004;70(3):265–7.

    Article  PubMed  Google Scholar 

  16. Masala S, Lunardi P, Fiori R, et al. Vertebroplasty and kyphoplasty in the treatment of malignant vertebral fractures. J Chemother. 2004;16 Suppl 5:30–3.

    PubMed  Google Scholar 

  17. Yamada K, Matsumoto Y, Kita M, Yamamoto K, Kobayashi T, Takanaka T. Long-term pain relief effects in four patients undergoing percutaneous vertebroplasty for metastatic vertebral tumor. J Anesth. 2004;18(4):292–5.

    Article  PubMed  Google Scholar 

  18. Diamond TH, Hartwell T, Clarke W, Manoharan A. Percutaneous vertebroplasty for acute vertebral body fracture and deformity in multiple myeloma: a short report. Br J Haematol. 2004;124(4):485–7.

    Article  PubMed  Google Scholar 

  19. Shimony JS, Gilula LA, Zeller AJ, Brown DB. Percutaneous vertebroplasty for malignant compression fractures with epidural involvement. Radiology. 2004;232(3):846–53.

    Article  PubMed  Google Scholar 

  20. Jang JS, Lee SH. Efficacy of percutaneous vertebroplasty combined with radiotherapy in osteolytic metastatic spinal tumors. J Neurosurg Spine. 2005;2(3):243–8.

    Article  PubMed  Google Scholar 

  21. Verlaan JJ, van de Kraats EB, Oner FC, van Walsum T, Niessen WJ, Dhert WJ. Bone displacement and the role of longitudinal ligaments during balloon vertebroplasty in traumatic thoracolumbar fractures. Spine. 2005;30(16):1832–9.

    Article  PubMed  Google Scholar 

  22. Ross PD, Davis JW, Epstein RS, Wasnich RD. Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Ann Intern Med. 1991;114(11):919–23.

    Article  CAS  PubMed  Google Scholar 

  23. Lieberman I. Vertebral augmentation for osteoporotic and osteolytic vertebral compression fractures: vertebroplasty and kyphoplasty. In: Haid Jr RW, Subach BR, Rodts Jr GE, editors. Advances in spinal stabilization, vol. 16. Basel: Karge; 2003. p. 240–50.

    Chapter  Google Scholar 

  24. Uhthoff HK, Jaworski ZF. Bone loss in response to long-term immobilisation. J Bone Joint Surg Br. 1978;60-B(3):420–9.

    CAS  PubMed  Google Scholar 

  25. Silverman SL. The clinical consequences of vertebral compression fracture. Bone. 1992;13 Suppl 2:S27–31.

    Article  PubMed  Google Scholar 

  26. Cook DJ, Guyatt GH, Adachi JD, et al. Quality of life issues in women with vertebral fractures due to osteoporosis. Arthritis Rheum. 1993;36(6):750–6.

    Article  CAS  PubMed  Google Scholar 

  27. Gold DT. The clinical impact of vertebral fractures: quality of life in women with osteoporosis. Bone. 1996;18 Suppl 3:185S–9.

    Article  CAS  PubMed  Google Scholar 

  28. Schlaich C, Minne HW, Bruckner T, et al. Reduced pulmonary function in patients with spinal osteoporotic fractures. Osteoporos Int. 1998;8(3):261–7.

    Article  CAS  PubMed  Google Scholar 

  29. Lippuner K. Medical treatment of vertebral osteoporosis. Eur Spine J. 2003;12 Suppl 2:S132–41.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Diamond TH, Champion B, Clark WA. Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. Am J Med. 2003;114(4):257–65.

    Article  PubMed  Google Scholar 

  31. Li Y, Hai Y, Li L, Feng Y, Wang M, Cao G. Early effects of vertebroplasty or kyphoplasty versus conservative treatment of vertebral compression fractures in elderly polytrauma patients. Arch Orthop Trauma Surg. 2015;135(12):1633–6.

    Article  PubMed  Google Scholar 

  32. Chen AT, Cohen DB, Skolasky RL. Impact of nonoperative treatment, vertebroplasty, and kyphoplasty on survival and morbidity after vertebral compression fracture in the medicare population. J Bone Joint Surg Am. 2013;95(19):1729–36.

    Article  PubMed  Google Scholar 

  33. Tanigawa N, Komemushi A, Kariya S, et al. Percutaneous vertebroplasty: relationship between vertebral body bone marrow edema pattern on MR images and initial clinical response. Radiology. 2006;239:195–200.

    Article  PubMed  Google Scholar 

  34. Alvarez L, Perez-Higueras A, Granizo JJ, de Miguel I, Quinones D, Rossi RE. Predictors of outcomes of percutaneous vertebroplasty for osteoporotic vertebral fractures. Spine. 2005;30(1):87–92.

    Article  PubMed  Google Scholar 

  35. Barr JD, Jensen ME, Hirsch JA, McGraw JK, Barr RM, Brook AL, Meyers PM, Munk PL, Murphy KJ, O’Toole JE, Rasmussen PA, Ryken TC, Sanelli PC, Schwartzberg MS, Seidenwurm D, Tutton SM, Zoarski GH, Kuo MD, Rose SC, Cardella JF. Position statement on percutaneous vertebral augmentation: a consensus statement developed by the Society of Interventional Radiology (SIR), American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS), American College of Radiology (ACR), American Society of Neuroradiology (ASNR), American Society of Spine Radiology (ASSR), Canadian Interventional Radiology Association (CIRA), and the Society of NeuroInterventional Surgery (SNIS). J Vasc Interv Radiol. 2014;25(2): 171–81.

    Google Scholar 

  36. Barr JD, Barr MS, Lemley TJ, McCann RM. Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine. 2000;25(8):923–8.

    Article  CAS  PubMed  Google Scholar 

  37. Brown DB, Gilula LA, Sehgal M, Shimony JS. Treatment of chronic symptomatic vertebral compression fractures with percutaneous vertebroplasty. AJR Am J Roentgenol. 2004;182(2):319–22.

    Article  PubMed  Google Scholar 

  38. Brown DB, Glaiberman CB, Gilula LA, Shimony JS. Correlation between preprocedural MRI findings and clinical outcomes in the treatment of chronic symptomatic vertebral compression fractures with percutaneous vertebroplasty. AJR Am J Roentgenol. 2005;184(6):1951–5.

    Article  PubMed  Google Scholar 

  39. Irani FG, Morales JP, Sabharwal T, Dourado R, Gangi A, Adam A. Successful treatment of a chronic post-traumatic 5-year-old osteoporotic vertebral compression fracture by percutaneous vertebroplasty. Br J Radiol. 2005;78(927):261–364.

    Article  CAS  PubMed  Google Scholar 

  40. McGraw JK, Cardella J, Barr JD, et al. Society of Interventional Radiology quality improvement guidelines for percutaneous vertebroplasty. J Vasc Interv Radiol. 2003;14(7):827–31.

    Article  PubMed  Google Scholar 

  41. Stallmeyer MJ, Zoarski GH, Obuchowski AM. Optimizing patient selection in percutaneous vertebroplasty. J Vasc Interv Radiol. 2003;14(6):683–96.

    Article  PubMed  Google Scholar 

  42. Garfin SR, Lin G, Lieberman I. Retrospective analysis of the outcomes of balloon kyphoplasty to treat vertebral body compression fracture (VCF) refractory to medical management. Eur Spine J. 2001;10 Suppl 1:S7.

    Google Scholar 

  43. Garfin SR, Yuan HA, Reiley MA. New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine. 2001;26(14):1511–5.

    Article  CAS  PubMed  Google Scholar 

  44. Togawa D, Kovacic JJ, Bauer TW, Reinhardt MK, Brodke DS, Lieberman IH. Radiographic and histologic findings of vertebral augmentation using polymethylmethacrylate in the primate spine: percutaneous vertebroplasty versus kyphoplasty. Spine. 2006;31(1):E4–10.

    Article  PubMed  Google Scholar 

  45. Verlaan JJ, van de Kraats EB, Oner FC, van Walsum T, Niessen WJ, Dhert WJ. The reduction of endplate fractures during balloon vertebroplasty: a detailed radiological analysis of the treatment of burst fractures using pedicle screws, balloon vertebroplasty, and calcium phosphate cement. Spine. 2005;30(16):1840–5.

    Article  PubMed  Google Scholar 

  46. Phillips FM. Minimally invasive treatments of osteoporotic vertebral compression fractures. Spine. 2003;28 Suppl 15:S45–53.

    PubMed  Google Scholar 

  47. Gangi A, Kastler BA, Dietemann JL. Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. AJNR Am J Neuroradiol. 1994;15(1):83–6.

    CAS  PubMed  Google Scholar 

  48. Mathis JM, Wong W. Percutaneous vertebroplasty: technical considerations. J Vasc Interv Radiol. 2003;14(8):953–60.

    Article  PubMed  Google Scholar 

  49. Do HM. Intraosseous venography during percutaneous vertebroplasty: is it needed? AJNR Am J Neuroradiol. 2002;23(4):508–9.

    PubMed  Google Scholar 

  50. Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. AJNR Am J Neuroradiol. 1997;18(10):1897–904.

    CAS  PubMed  Google Scholar 

  51. McGraw JK, Heatwole EV, Strnad BT, Silber JS, Patzilk SB, Boorstein JM. Predictive value of intraosseous venography before percutaneous vertebroplasty. J Vasc Interv Radiol. 2002;13(2 Pt 1):149–53.

    Article  PubMed  Google Scholar 

  52. Gaughen Jr JR, Jensen ME, Schweickert PA, Kaufmann TJ, Marx WF, Kallmes DF. Relevance of antecedent venography in percutaneous vertebroplasty for the treatment of osteoporotic compression fractures. AJNR Am J Neuroradiol. 2002;23(4):594–600.

    PubMed  Google Scholar 

  53. Vasconcelos C, Gailloud P, Beauchamp NJ, Heck DV, Murphy KJ. Is percutaneous vertebroplasty without pretreatment venography safe? Evaluation of 205 consecutives procedures. AJNR Am J Neuroradiol. 2002;23(6):913–7.

    PubMed  Google Scholar 

  54. Wong W, Mathis J. Is intraosseous venography a significant safety measure in performance of vertebroplasty? J Vasc Interv Radiol. 2002;13(2 Pt 1):137–8.

    Article  PubMed  Google Scholar 

  55. Belkoff SM, Molloy S. Temperature measurement during polymerization of polymethylmethacrylate cement used for vertebroplasty. Spine. 2003;28(14):1555–9.

    PubMed  Google Scholar 

  56. Lieberman IH, Dudeney S, Reinhardt MK, Bell G. Initial outcome and efficacy of “kyphoplasty” in the treatment of painful osteoporotic vertebral compression fractures. Spine. 2001;26(14):1631–8.

    Article  CAS  PubMed  Google Scholar 

  57. Dublin AB, Hartman J, Latchaw RE, Hald JK, Reid MH. The vertebral body fracture in osteoporosis: restoration of height using percutaneous vertebroplasty. AJNR Am J Neuroradiol. 2005;26(3):489–92.

    PubMed  Google Scholar 

  58. McKiernan F, Faciszewski T, Jensen R. Does vertebral height restoration achieved at vertebroplasty matter? J Vasc Interv Radiol. 2005;16(7):973–9.

    Article  PubMed  Google Scholar 

  59. Chiras J, Depriester C, Weill A, Sola-Martinez MT, Deramond H. Percutaneous vertebral surgery. Technics and indications. J Neuroradiol. 1997;24(1):45–59.

    CAS  PubMed  Google Scholar 

  60. Cortet B, Cotten A, Boutry N, et al. Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study. J Rheumatol. 1999;26(10):2222–8.

    CAS  PubMed  Google Scholar 

  61. Teng MM, Cheng H, Ho DM, Chang CY. Intraspinal leakage of bone cement after vertebroplasty: a report of 3 cases. AJNR Am J Neuroradiol. 2006;27(1):224–9.

    CAS  PubMed  Google Scholar 

  62. du Choe H, Marom EM, Ahrar K, Truong MT, Madewell JE. Pulmonary embolism of polymethyl methacrylate during percutaneous vertebroplasty and kyphoplasty. AJR Am J Roentgenol. 2004;183(4):1097–102.

    Article  PubMed  Google Scholar 

  63. Monticelli F, Meyer HJ, Tutsch-Bauer E. Fatal pulmonary cement embolism following percutaneous vertebroplasty (PVP). Forensic Sci Int. 2005;149(1):35–8.

    Article  CAS  PubMed  Google Scholar 

  64. Pott L, Wippermann B, Hussein S, Gunther T, Brusch U, Fremerey R. PMMA pulmonary embolism and post interventional associated fractures after percutaneous vertebroplasty. Orthopade. 2005;34(7):698–700. 702.

    Article  CAS  PubMed  Google Scholar 

  65. Righini M, Sekoranja L, Le Gal G, Favre I, Bounameaux H, Janssens JP. Pulmonary cement embolism after vertebroplasty. Thromb Haemost. 2006;95(2):388–9.

    CAS  PubMed  Google Scholar 

  66. Yoo KY, Jeong SW, Yoon W, Lee J. Acute respiratory distress syndrome associated with pulmonary cement embolism following percutaneous vertebroplasty with polymethylmethacrylate. Spine. 2004;29(14):E294–7.

    Article  PubMed  Google Scholar 

  67. Padovani B, Kasriel O, Brunner P, Peretti-Viton P. Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty. AJNR Am J Neuroradiol. 1999;20(3):375–7.

    CAS  PubMed  Google Scholar 

  68. Baumann A, Tauss J, Baumann G, Tomka M, Hessinger M, Tiesenhausen K. Cement embolization into the vena cava and pulmonal arteries after vertebroplasty: interdisciplinary management. Eur J Vasc Endovasc Surg. 2005;31(5):558–61.

    Article  PubMed  Google Scholar 

  69. Chung SE, Lee SH, Kim TH, Yoo KH, Jo BJ. Renal cement embolism during percutaneous vertebroplasty. Eur Spine J. 2006;15 Suppl 5:590–4.

    Article  PubMed  Google Scholar 

  70. Freitag M, Gottschalk A, Schuster M, Wenk W, Wiesner L, Standl TG. Pulmonary embolism caused by polymethylmethacrylate during percutaneous vertebroplasty in orthopaedic surgery. Acta Anaesthesiol Scand. 2006;50(2):248–51.

    Article  CAS  PubMed  Google Scholar 

  71. Childers Jr JC. Cardiovascular collapse and death during vertebroplasty. Radiology. 2003;228(3):902. author reply 902–903.

    Article  PubMed  Google Scholar 

  72. Park JH, Choo SJ, Park SW. Images in cardiovascular medicine. Acute pericarditis caused by acrylic bone cement after percutaneous vertebroplasty. Circulation. 2005;111(6):e98.

    Article  PubMed  Google Scholar 

  73. Schmid KE, Boszczyk BM, Bierschneider M, Zarfl A, Robert B, Jaksche H. Spondylitis following vertebroplasty: a case report. Eur Spine J. 2005;14(9):895–9.

    Article  PubMed  Google Scholar 

  74. Walker DH, Mummaneni P, Rodts Jr GE. Infected vertebroplasty. Report of two cases and review of the literature. Neurosurg Focus. 2004;17(6):E6.

    Article  PubMed  Google Scholar 

  75. Yu SW, Chen WJ, Lin WC, Chen YJ, Tu YK. Serious pyogenic spondylitis following vertebroplasty – a case report. Spine. 2004;29(10):E209–11.

    Article  PubMed  Google Scholar 

  76. Kim SY, Seo JB, Do KH, Lee JS, Song KS, Lim TH. Cardiac perforation caused by acrylic cement: a rare complication of percutaneous vertebroplasty. AJR Am J Roentgenol. 2005;185(5):1245–7.

    Article  PubMed  Google Scholar 

  77. Syed MI, Jan S, Patel NA, Shaikh A, Marsh RA, Stewart RV. Fatal fat embolism after vertebroplasty: identification of the high-risk patient. AJNR Am J Neuroradiol. 2006;27(2):343–5.

    CAS  PubMed  Google Scholar 

  78. Syed MI, Patel NA, Jan S, Harron MS, Morar K, Shaikh A. New symptomatic vertebral compression fractures within a year following vertebroplasty in osteoporotic women. AJNR Am J Neuroradiol. 2005;26(6):1601–4.

    PubMed  Google Scholar 

  79. Tanigawa N, Komemushi A, Kariya S, Kojima H, Shomura Y, Sawada S. Radiological follow-up of new compression fractures following percutaneous vertebroplasty. Cardiovasc Intervent Radiol. 2006;29(1):92–6.

    Article  PubMed  Google Scholar 

  80. Kim SH, Kang HS, Choi JA, Ahn JM. Risk factors of new compression fractures in adjacent vertebrae after percutaneous vertebroplasty. Acta Radiol. 2004;45(4):440–5.

    Article  CAS  PubMed  Google Scholar 

  81. Lin EP, Ekholm S, Hiwatashi A, Westesson PL. Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol. 2004;25(2):175–80.

    PubMed  Google Scholar 

  82. Mehdizade A, Lovblad KO, Wilhelm KE, et al. Radiation dose in vertebroplasty. Neuroradiology. 2004;46(3):243–5.

    Article  CAS  PubMed  Google Scholar 

  83. Kruger R, Faciszewski T. Radiation dose reduction to medical staff during vertebroplasty: a review of techniques and methods to mitigate occupational dose. Spine. 2003;28(14):1608–13.

    PubMed  Google Scholar 

  84. Evans AJ, Kip KE, Brinjikji W, Layton KF, Jensen ML, Gaughen JR, Kallmes DF. Randomized controlled trial of vertebroplasty versus kyphoplasty in the treatment of vertebral compression fractures. J Neurointerv Surg. 2015; pii: neurintsurg-2015-011811. doi:10.1136/neurintsurg-2015-011811 (Epub ahead of print)

    Google Scholar 

  85. Wang H, Sribastav SS, Ye F, Yang C, Wang J, Liu H, Zheng Z. Comparison of percutaneous vertebroplasty and balloon kyphoplasty for the treatment of single level vertebral compression fractures: a meta-analysis of the literature. Pain. 2015;18(3):209–22.

    Google Scholar 

  86. Huang Z, Wan S, Ning L, Han S. Is unilateral kyphoplasty as effective and safe as bilateral kyphoplasties for osteoporotic vertebral compression fractures? A meta-analysis. Clin Orthop Relat Res. 2014;472(9):2833–42.

    Article  PubMed  PubMed Central  Google Scholar 

  87. Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. Radiol Clin North Am. 1998;36(3):533–46.

    Article  CAS  PubMed  Google Scholar 

  88. Perez-Higueras A, Alvarez L, Rossi RE, Quinones D, Al-Assir I. Percutaneous vertebroplasty: long-term clinical and radiological outcome. Neuroradiology. 2002;44(11):950–4.

    Article  CAS  PubMed  Google Scholar 

  89. Cortet B, Cotten A, Boutry N, et al. Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma. Rev Rhum Engl Ed. 1997;64(3):177–83.

    CAS  PubMed  Google Scholar 

  90. Dudeney S, Lieberman IH, Reinhardt MK, Hussein M. Kyphoplasty in the treatment of osteolytic vertebral compression fractures as a result of multiple myeloma. J Clin Oncol. 2002;20(9):2382–7.

    Article  CAS  PubMed  Google Scholar 

  91. Kumar K, Verma AK, Wilson J, LaFontaine A. Vertebroplasty in osteoporotic spine fractures: a quality of life assessment. Can J Neurol Sci. 2005;32(4):487–95.

    Article  PubMed  Google Scholar 

  92. McKiernan F, Faciszewski T, Jensen R. Quality of life following vertebroplasty. J Bone Joint Surg Am. 2004;86-A(12):2600–6.

    PubMed  Google Scholar 

  93. Winking M, Stahl JP, Oertel M, Schnettler R, Boker DK. Treatment of pain from osteoporotic vertebral collapse by percutaneous PMMA vertebroplasty. Acta Neurochir (Wien). 2004;146(5):469–76.

    Article  CAS  Google Scholar 

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Fessler, R.D., Lebow, R.L., O’Toole, J.E., Fessler, R.G., Eichholz, K.M. (2016). Percutaneous Vertebral Augmentation: Vertebroplasty and Kyphoplasty. In: Scuderi, G., Tria, A. (eds) Minimally Invasive Surgery in Orthopedics. Springer, Cham. https://doi.org/10.1007/978-3-319-34109-5_109

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