Abstract
Chronic pruritus accompanies a broad range of systemic disorders among which are hematologic and lymphoproliferative disorders, metabolic and endocrine diseases, solid tumours, and infectious diseases. Among endocrine disorders chronic pruritus is commonly observed in patients suffering from diabetes mellitus, thyroid and parathyroid disorders, anorexia nervosa, celiac disease, carcinoid syndrome, and multiple endocrine neoplasia type 2. The molecular mechanisms involved in pruritus in these diseases remain largely enigmatic. Treatment options are limited as so far no clinical studies have been performed addressing itching in endocrine disorders.
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Abbreviations
- MEN2A:
-
Multiple endocrine neoplasia type 2A
- PTH:
-
Parathyroid hormone
- TNF:
-
Tumour necrosis factor
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Kremer, A.E., Weisshaar, E. (2016). Endocrine Diseases. In: Misery, L., Ständer, S. (eds) Pruritus. Springer, Cham. https://doi.org/10.1007/978-3-319-33142-3_35
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DOI: https://doi.org/10.1007/978-3-319-33142-3_35
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