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Mechanical Properties of Three Different Types of Skin Graft

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Agache's Measuring the Skin

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Abstract

Artificial dermis is widely used in the treatment of excessive burn injuries and is also more and more used in reconstructive surgery. The collagen/glycosaminoglycan matrix becomes vascularized and metabolically incorporated into the body, in a manner similar to that of composite or full-thickness skin grafts. The use of artificial dermis increases qualities of split-thickness skin graft and can avoid flaps to cover avascular beds with the phenomenon of bridging.

Artificial dermis is an excellent option for reconstructing defects created by tumor excision, especially in elderly population, and can be used in a wide variety of locations.

After a review of literature about the use of artificial dermis for oncologic surgical defects, we report and discuss our experiment with the first clinical cases in our department.

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Acknowledgments

The author thanks the companies Skinexigence and Perimed, as well as the laboratory of anatomo-pathology, in particular Professor Kantelip and Dr Algros for their contribution to this article.

There is no conflict of interest.

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Authors and Affiliations

  1. Orthopedic Surgery, Traumatology, Plastic Aesthetic, Reconstructive Surgery, and Hand Surgery Department, EA 4268, IFR 133 INSERM I4S, Besançon University Hospital, Besançon, France

    J. Pauchot

  2. Center for Research and Studies on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC INSERM 1431), Besançon University Hospital; INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

    Alexandre Guichard & Thomas Lihoreau

  3. Center for Research and Studies on the Integument (CERT), Department of Dermatology, Clinical Investigation Center (CIC BT506), Besançon University Hospital, INSERM UMR1098, FED4234 IBCT, University of Franche-Comté, Besançon, France

    Ahmed Elkhyat

  4. Skinexigence SAS, Bioparc, Besançon, France

    Sophie Mac-Mary

  5. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Philippe Humbert

Authors
  1. J. Pauchot
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  2. Alexandre Guichard
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  3. Thomas Lihoreau
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  4. Ahmed Elkhyat
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  5. Sophie Mac-Mary
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  6. Philippe Humbert
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Corresponding author

Correspondence to J. Pauchot .

Editor information

Editors and Affiliations

  1. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Philippe Humbert

  2. Center for Study and Research on the Integuments, Department of Dermatology, University Hospital of Besançon, Besançon, France

    Ferial Fanian

  3. Department of Dermatology, School of Medicine, University of California, San Francisco, California, USA

    Howard I. Maibach

  4. Department of Dermatology, University Hospital of Besançon, Besançon, France

    Pierre Agache

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Pauchot, J., Guichard, A., Lihoreau, T., Elkhyat, A., Mac-Mary, S., Humbert, P. (2017). Mechanical Properties of Three Different Types of Skin Graft. In: Humbert, P., Fanian, F., Maibach, H., Agache, P. (eds) Agache's Measuring the Skin. Springer, Cham. https://doi.org/10.1007/978-3-319-32383-1_149

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  • DOI: https://doi.org/10.1007/978-3-319-32383-1_149

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-319-32383-1

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