Skip to main content

Accuracy, Precision, Sensitivity, and Specificity of Noninvasive ICP Absolute Value Measurements

  • Chapter
Intracranial Pressure and Brain Monitoring XV

Abstract

An innovative absolute intracranial pressure (ICP) value measurement method has been validated by multicenter comparative clinical studies. The method is based on two-depth transcranial Doppler (TCD) technology and uses intracranial and extracranial segments of the ophthalmic artery as pressure sensors. The ophthalmic artery is used as a natural pair of “scales” that compares ICP with controlled pressure Pe, which is externally applied to the orbit. To balance the scales, ICP = Pe a special two-depth TCD device was used as a pressure balance indicator. The proposed method is the only noninvasive ICP measurement method that does not need patient-specific calibration.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Czosnyka M, Pickard JD (2004) Monitoring and interpretation of intracranial pressure. J Neurol Neurosurg Psychiatry 75:813–821

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Kimberly HH, Shah S, Marill K, Noble V (2008) Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure. Acad Emerg Med 15:201–204

    Article  PubMed  Google Scholar 

  3. Buki B, Avan P, Lemaire JJ, Dordain M, Chazal J, Ribari O (1996) Otoacoustic emissions: a new tool for monitoring intracranial pressure through stapes displacement. Hear Res 94:125–139

    Article  CAS  PubMed  Google Scholar 

  4. Geeraerts T, Launey Y, Martin L, Pottecher J, Vigue B, Duranteau J et al (2007) Ultrasonography of the optic nerve sheath may be useful for detecting raised intracranial pressure after brain injury. Intensive Care Med 33:1704–1711

    Article  PubMed  Google Scholar 

  5. Kristiansson H, Nissborg E, Jr Bartek J, Andersen M, Reinstrup P, Romner B (2013) Measuring elevated intracranial pressure through noninvasive methods: a review of the literature. J Neurosurg Anesthesiol 25:372–385

    Article  PubMed  Google Scholar 

  6. Wu J, He W, Chen WM, Zhu L (2013) Research on simulation and experiment of noninvasive intracranial pressure monitoring based on acoustoelasticity effects. Med Devices (Auckl) 6:123–131

    Article  Google Scholar 

  7. Cyrous A, O’neal B, Freeman WD (2012) New approaches to bedside monitoring in stroke. Expert Rev Neurother 12:915–928

    Article  CAS  PubMed  Google Scholar 

  8. Raboel PH, Jr Bartek J, Andersen M, Bellander BM, Romner B (2012) Intracranial pressure monitoring: invasive versus non-invasive methods – a review. Crit Care Res Pract 2012:950393

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Muchnok T, Deitch K, Giraldo P (2012) Can intraocular pressure measurements be used to screen for elevated intracranial pressure in emergency department patients? J Emerg Med 43:532–537

    Article  PubMed  Google Scholar 

  10. Shaw M, Piper I, Campbell P et al (2012) Investigation of the relationship between transcranial impedance and intracranial pressure. Acta Neurochir Suppl 114:61–65

    Article  PubMed  Google Scholar 

  11. Ragauskas A, Petkus V, Chomskis R, Zakelis R, Daubaris G, Moehring M, Saxon EA, Giansiracusa R, Swedenburg S, Raisutis R (2013) Method and apparatus for determining the absolute value of intracranial pressure. US Patent No. 8,394,025, 12 Mar 2013

    Google Scholar 

  12. Ragauskas A, Daubaris G, Dziugys A, Azelis V, Gedrimas V (2005) Innovative non-invasive method for absolute intracranial pressure measurement without calibration. Acta Neurochir Suppl 95:357–361

    Article  CAS  PubMed  Google Scholar 

  13. Ragauskas A, Matijosaitis V, Zakelis R, Petrikonis K, Rastenyte D, Piper I, Daubaris G (2012) Clinical assessment of noninvasive intracranial pressure absolute value measurement method. Neurology 78:1684–1691

    Article  CAS  PubMed  Google Scholar 

  14. Ragauskas A, Bartusis L, Piper I, Zakelis R, Matijosaitis V, Petrikonis K, Rastenyte D (2014) Improved diagnostic value of a TCD-based non-invasive ICP measurement method compared with the sonographic ONSD method for detecting elevated intracranial pressure. Neurol Res 36:607–614

    Article  PubMed  Google Scholar 

  15. Alperin N, Lee SH, Loth F, Raksin P, Lichto T (2000) MR-intracranial pressure (ICP): a method for noninvasive measurement of intracranial pressure and elastance. Baboon and Human Study. Radiology 217:877–885

    Article  CAS  PubMed  Google Scholar 

  16. Alperin N, Hushek SG, Lee SH, Sivaramakrishnan A, Lichtor T (2005) MRI study of cerebral blood flow and CSF flow dynamics in an upright posture: the effect of posture on the intracranial compliance and pressure. Acta Neurochir Suppl 95:177–181

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported by the European Commission’s Seventh Framework Programme projects: “BrainSafe” (grant agreement No.: 232545), “BrainSafe II” (grant agreement No: 315549), “TBIcare” (grant agreement No: 270259) and also by NSBRI (NASA).

Conflict of Interest

Professor Arminas Ragauskas is the inventor of the patented noninvasive absolute ICP measurement method.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Arminas Ragauskas .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Krakauskaite, S. et al. (2016). Accuracy, Precision, Sensitivity, and Specificity of Noninvasive ICP Absolute Value Measurements. In: Ang, BT. (eds) Intracranial Pressure and Brain Monitoring XV. Acta Neurochirurgica Supplement, vol 122. Springer, Cham. https://doi.org/10.1007/978-3-319-22533-3_63

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-22533-3_63

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22532-6

  • Online ISBN: 978-3-319-22533-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics