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Noninvasive Approaches to Enhance Ovarian Function

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Primary Ovarian Insufficiency

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Abstract

While it is widely accepted that in vitro fertilization (IVF) utilizing donor oocytes provides the most reliable, evidence-based treatment for patients with POI desiring pregnancy, there is some evidence suggesting that POI can be treated with less invasive therapy, especially in the earlier stages of diagnosis. Ovulation induction, superovulation, supplemental hormone therapy, and lifestyle changes may be considered as noninvasive methods to improve ovarian function, although the evidence is limited by size and methodology. While further research is needed to improve the noninvasive options for fertility treatment in patients with POI, it is reasonable to consider these methods if the patient is unable or unwilling to undergo donor oocyte IVF. This chapter will highlight several noninvasive methods for potentially improving ovarian function and introduce emerging therapies that may be worth consideration prior to more aggressive treatment.

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Author information

Authors and Affiliations

  1. Kaiser Permanente Northern California, 1650 Response Road, 1A, Sacramento, CA, 95815, USA

    Lisa Marii Cookingham MD

  2. Colorado Center for Reproductive Medicine, 10290 RidgeGate Circle, Lone Tree, CO, 80124, USA

    Laxmi A. Kondapalli MD, MSCE

Authors
  1. Lisa Marii Cookingham MD
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  2. Laxmi A. Kondapalli MD, MSCE
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Corresponding author

Correspondence to Laxmi A. Kondapalli MD, MSCE .

Editor information

Editors and Affiliations

  1. Obstetrics and Gynecology, University of Colorado, Aurora, Colorado, USA

    Nanette F. Santoro

  2. Obstetrics and Gynecology, Washington University, St. Louis, Missouri, USA

    Amber R. Cooper

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© 2016 Springer International Publishing Switzerland

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Cookingham, L.M., Kondapalli, L.A. (2016). Noninvasive Approaches to Enhance Ovarian Function. In: Santoro, N., Cooper, A. (eds) Primary Ovarian Insufficiency. Springer, Cham. https://doi.org/10.1007/978-3-319-22491-6_7

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  • DOI: https://doi.org/10.1007/978-3-319-22491-6_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22490-9

  • Online ISBN: 978-3-319-22491-6

  • eBook Packages: MedicineMedicine (R0)

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