Abstract
Stepwise diversification. The coeloma cavities of the deuterostome sea urchins (Strongylocentrotus purpuratus) mobilize monocyte-like cells, which respond to bacterial endotoxins. The diversity of the response of sea urchin coelomocytes to lipopolysaccharides was unexpectedly high: 81 full length cDNAs contained 67 unique nucleotide sequences (the 185/333 family) encoding 64 different proteins. Complement C3 was expressed, too.
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Sinkovics, J.G. (2016). A Highly Effective Immune System Predating Adaptive Immunity. In: RNA/DNA and Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-22279-0_5
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DOI: https://doi.org/10.1007/978-3-319-22279-0_5
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