Abstract
Lung cancer remains the leading cause of cancer-related mortality in the developing world. Smoking is the most important preventable risk factor and strong public health efforts are needed to curtail this. Most patients with lung cancer have advanced disease at presentation; hence, the survival rates are poor. The role of screening low-dose CT for early detection of lung cancer has not been evaluated in the tropics and hence cannot be recommended in these areas. The standard of care for early-stage lung cancers remains surgical resection.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ferlaly J, Soerjomataram I, Dikshit R et al (2015). Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136: E359–E386
Behera D, Balamugesh T (2004) Lung cancer in India. Indian J Chest Dis Allied Sci 46:269–281
Parkin DM, Bray F, Ferlay J et al (2005) Global cancer statistics, 2002. CA Cancer J Clin 55:74–108
Janssen-Heijnen ML, Coebergh JW (2003) The changing epidemiology of lung cancer in Europe. Lung Cancer 41:245–258
Thun MJ, Lally CA, Flannery JT et al (1997) Cigarette smoking and changes in the histopathology of lung cancer. J Natl Cancer Inst 89:1580–1586
Bach PB, Kattan MW, Thornquist MD et al (2003) Variations in lung cancer risk among smokers. J Natl Cancer Inst 95:470–478
Lee PN, Forey BA (2013) Indirectly estimated absolute lung cancer mortality rates by smoking status and histological type based on a systematic review. BMC Cancer 13:189
Prasad R, Singhal S, Garg R (2009) Bidi smoking and lung cancer. Biosci Trends 3:41–43
Asomaning K, Miller DP, Liu G et al (2008) Second hand smoke, age of exposure and lung cancer risk. Lung Cancer 61:13–20
Humans IWGotEoCRt (2010) Household use of solid fuels and high-temperature frying. IARC Monogr Eval Carcinog Risks Hum 95:1–430
Kurmi OP, Arya PH, Lam KB et al (2012) Lung cancer risk and solid fuel smoke exposure: a systematic review and meta-analysis. Eur Respir J 40:1228–1237
Yorifuji T, Kashima S (2013) Air pollution: another cause of lung cancer. Lancet Oncol 14:788–789
Groome PA, Bolejack V, Crowley JJ et al (2007) The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol 2:694–705
De Wever W, Stroobants S, Coolen J et al (2009) Integrated PET/CT in the staging of nonsmall cell lung cancer: technical aspects and clinical integration. Eur Respir J 33:201–212
Annema JT, van Meerbeeck JP, Rintoul RC et al (2010) Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial. JAMA 304:2245–2252
Koike T, Yamato Y, Yoshiya K et al (2003) Intentional limited pulmonary resection for peripheral T1 N0 M0 small-sized lung cancer. J Thorac Cardiovasc Surg 125:924–928
Okada M, Koike T, Higashiyama M et al (2006) Radical sublobar resection for small-sized non-small cell lung cancer: a multicenter study. J Thorac Cardiovasc Surg 132:769–775
Sugi K, Kaneda Y, Esato K (2000) Video-assisted thoracoscopic lobectomy achieves a satisfactory long-term prognosis in patients with clinical stage IA lung cancer. World J Surg 24:27–30; discussion 30–21
Strauss GM, Herndon JE 2nd, Maddaus MA et al (2008) Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups. J Clin Oncol 26:5043–5051
Timmerman RD, Herman J, Cho LC (2014) Emergence of stereotactic body radiation therapy and its impact on current and future clinical practice. J Clin Oncol 32:2847–2854
Pignon JP, Tribodet H, Scagliotti GV et al (2008) Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group. J Clin Oncol 26:3552–3559
Ramnath N, Dilling TJ, Harris LJ et al (2013) Treatment of stage III non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143:e314S–e340S
Ardizzoni A, Boni L, Tiseo M et al (2007) Cisplatin- versus carboplatin-based chemotherapy in first-line treatment of advanced non-small-cell lung cancer: an individual patient data meta-analysis. J Natl Cancer Inst 99:847–857
Scagliotti GV, Parikh P, von Pawel J et al (2008) Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 26:3543–3551
Azzoli CG, Temin S, Aliff T et al (2011) 2011 Focused Update of 2009 American Society of clinical oncology clinical practice guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 29:3825–3831
Lima JP, dos Santos LV, Sasse EC et al (2010) Camptothecins compared with etoposide in combination with platinum analog in extensive stage small cell lung cancer: systematic review with meta-analysis. J Thorac Oncol 5:1986–1993
Prophylactic Cranial Irradiation Overview Collaborative Group (2000) Cranial irradiation for preventing brain metastases of small cell lung cancer in patients in complete remission. Cochrane Database Syst Rev (4):CD002805
Weksler B, Nason KS, Shende M et al (2012) Surgical resection should be considered for stage I and II small cell carcinoma of the lung. Ann Thorac Surg 94:889–893
Shi Y, Au JS, Thongprasert S et al (2014) A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER). J Thorac Oncol 9:154–162
Savas P, Hughes B, Solomon B (2013) Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer. J Thorac Dis 5:S579–S592
Solomon BJ, Mok T, Kim D-W, Wu Y-L et al (2014) First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 371:2167–2177
Shaw AT, Kim DW, Nakagawa K et al (2013) Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 368:2385–2394
Shaw AT, Ou S-H, Bang Y-J, Camidge DR et al (2014) Crizotinib in ROS1-rearranged non-small-cell lung cancer. N Engl J Med 371:1963–1971
Soria JC, Mauguen A, Reck M et al (2013) Systematic review and meta-analysis of randomised, phase II/III trials adding bevacizumab to platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer. Ann Oncol 24:20–30
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Behera, D., Maturu, V.N. (2015). Lung Cancer. In: Droz, JP., Carme, B., Couppié, P., Nacher, M., Thiéblemont, C. (eds) Tropical Hemato-Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-18257-5_37
Download citation
DOI: https://doi.org/10.1007/978-3-319-18257-5_37
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-18256-8
Online ISBN: 978-3-319-18257-5
eBook Packages: MedicineMedicine (R0)