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Nutritional Supplements for Endurance Athletes

  • Chapter
Nutritional Supplements in Sports and Exercise

Abstract

Endurance athletes often seek nutritional strategies inclusive of dietary supplements to maximize their performance. Effective supplement routines, however, are only beneficial when built on a sound training diet, training regimen, and an appreciation of dietary needs relative to their training schema. While traditional dietary interventions are based on the glycemic index of carbohydrate, coupled with the addition of protein quality and quantity, recent innovations have introduced the potential utility of long chain glucose polymers and dietary nitrates, such as beetroot juice. Consideration is also given to the utility of supplement strategies aimed at attenuating immune responses accompanying training and competition. A key to implementing successful supplementation routines is the appreciation that athletes should be considered on an individual basis and training volume and intensity must be taken into account.

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References

  1. Bell DG, Jacobs I. Combined caffeine and ephedrine ingestion improves run times of Canadian Forces Warrior Test. Aviat Space Environ Med. 1999;70(4):325–9.

    CAS  PubMed  Google Scholar 

  2. Blomstrand E, Hassmen P, Ekblom B, Newsholme EA. Administration of branched-chain amino acids during sustained exercise–effects on performance and on plasma concentration of some amino acids. Eur J Appl Physiol Occup Physiol. 1991;63(2):83–8.

    Article  CAS  PubMed  Google Scholar 

  3. Bridge CA, Jones MA. The effect of caffeine ingestion on 8 km run performance in a field setting. J Sports Sci. 2006;24(4):433–9.

    Article  CAS  PubMed  Google Scholar 

  4. Kreider RB, Miller GW, Williams MH, Somma CT, Nasser TA. Effects of phosphate loading on oxygen uptake, ventilatory anaerobic threshold, and run performance. Med Sci Sports Exerc. 1990;22(2):250–6.

    Article  CAS  PubMed  Google Scholar 

  5. Coyle EF, Montain SJ. Benefits of fluid replacement with carbohydrate during exercise. Med Sci Sports Exerc. 1992;24(9 Suppl):S324–30.

    CAS  PubMed  Google Scholar 

  6. Armstrong LE, Costill DL, Fink WJ. Influence of diuretic-induced dehydration on competitive running performance. Med Sci Sports Exerc. 1985; 17(4):456–61.

    Article  CAS  PubMed  Google Scholar 

  7. Sutton JR, Bar-Or O. Thermal illness in fun running. Am Heart J. 1980;100(6 Pt 1):778–81.

    Article  CAS  PubMed  Google Scholar 

  8. Coyle EF. Substrate utilization during exercise in active people. Am J Clin Nutr. 1995;61(4 Suppl):968S–79.

    CAS  PubMed  Google Scholar 

  9. Krieder RB, Fry AC, O’Toole ML, editors. Overtraining in sport. Champaign, IL: Human Kinetics; 1998.

    Google Scholar 

  10. Cade JR, Reese RH, Privette RM, Hommen NM, Rogers JL, Fregly MJ. Dietary intervention and training in swimmers. Eur J Appl Physiol Occup Physiol. 1991;63(3–4):210–5.

    Article  CAS  PubMed  Google Scholar 

  11. Carli G, Bonifazi M, Lodi L, Lupo C, Martelli G, Viti A. Changes in the exercise-induced hormone response to branched chain amino acid administration. Eur J Appl Physiol Occup Physiol. 1992;64(3):272–7.

    Article  CAS  PubMed  Google Scholar 

  12. Kreider RB. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med. 1999;27(2):97–110.

    Article  CAS  PubMed  Google Scholar 

  13. Komi PV. Strength and power in sport. Cambridge, MA: Blackwell Scientific; 1992.

    Google Scholar 

  14. Coyle EF, Montain SJ. Carbohydrate and fluid ingestion during exercise: are there trade-offs? Med Sci Sports Exerc. 1992;24(6):671–8.

    Article  CAS  PubMed  Google Scholar 

  15. Noakes TD, Myburgh KH, du Plessis J, Lang L, Lambert M, van der Riet C, et al. Metabolic rate, not percent dehydration, predicts rectal temperature in marathon runners. Med Sci Sports Exerc. 1991; 23(4):443–9.

    Article  CAS  PubMed  Google Scholar 

  16. Klimberg VS, Nwokedi E, Hutchins LF, Pappas AA, Lang NP, Broadwater JR, et al. Glutamine facilitates chemotherapy while reducing toxicity. JPEN J Parenter Enteral Nutr. 1992;16(6 Suppl):83S–7.

    Article  CAS  PubMed  Google Scholar 

  17. Bergstrom J, Hermansen L, Hultman E, Saltin B. Diet, muscle glycogen and physical performance. Acta Physiol Scand. 1967;71(2):140–50.

    Article  CAS  PubMed  Google Scholar 

  18. Gastelu D, Hatfield FC. Nutrition for maximum performance. Garden City Park, NY: Avery; 1997.

    Google Scholar 

  19. Andersen LL, Tufekovic G, Zebis MK, Crameri RM, Verlaan G, Kjaer M, et al. The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength. Metabolism. 2005;54(2):151–6.

    Article  CAS  PubMed  Google Scholar 

  20. Ivy JL, Res PT, Sprague RC, Widzer MO. Effect of a carbohydrate-protein supplement on endurance performance during exercise of varying intensity. Int J Sport Nutr Exerc Metab. 2003;13(3):382–95.

    CAS  PubMed  Google Scholar 

  21. Saunders MJ, Kane MD, Todd MK. Effects of a carbohydrate-protein beverage on cycling endurance and muscle damage. Med Sci Sports Exerc. 2004; 36(7):1233–8.

    Article  CAS  PubMed  Google Scholar 

  22. Dangin M, Boirie Y, Garcia-Rodenas C, Gachon P, Fauquant J, Callier P, et al. The digestion rate of protein is an independent regulating factor of postprandial protein retention. Am J Physiol Endocrinol Metab. 2001;280(2):E340–8.

    CAS  PubMed  Google Scholar 

  23. Ivy J, Portman R. The performance zone. North Bergen, NJ: Basic Health; 2004.

    Google Scholar 

  24. Costill DL, Hargreaves M. Carbohydrate nutrition and fatigue. Sports Med. 1992;13(2):86–92.

    Article  CAS  PubMed  Google Scholar 

  25. Ivy JL. Muscle glycogen synthesis before and after exercise. Sports Med. 1991;11(1):6–19.

    Article  CAS  PubMed  Google Scholar 

  26. Ivy JL. Glycogen resynthesis after exercise: effect of carbohydrate intake. Int J Sports Med. 1998;19 Suppl 2:S142–5.

    Article  CAS  PubMed  Google Scholar 

  27. Haymond MW. Hypoglycemia in infants and children. Endocrinol Metab Clin North Am. 1989;18(1):211–52.

    CAS  PubMed  Google Scholar 

  28. Blom PC, Hostmark AT, Vaage O, Kardel KR, Maehlum S. Effect of different post-exercise sugar diets on the rate of muscle glycogen synthesis. Med Sci Sports Exerc. 1987;19(5):491–6.

    Article  CAS  PubMed  Google Scholar 

  29. Burke LM, Collier GR, Hargreaves M. Muscle glycogen storage after prolonged exercise: effect of the glycemic index of carbohydrate feedings. J Appl Physiol. 1993;75(2):1019–23.

    CAS  PubMed  Google Scholar 

  30. Jentjens RL, van Loon LJ, Mann CH, Wagenmakers AJ, Jeukendrup AE. Addition of protein and amino acids to carbohydrates does not enhance postexercise muscle glycogen synthesis. J Appl Physiol. 2001;91(2):839–46.

    CAS  PubMed  Google Scholar 

  31. Tarnopolsky MA, Bosman M, Macdonald JR, Vandeputte D, Martin J, Roy BD. Postexercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol. 1997;83(6):1877–83.

    CAS  PubMed  Google Scholar 

  32. Evans WJ. Protein nutrition and resistance exercise. Can J Appl Physiol. 2001;26(Suppl):S141–52.

    Article  PubMed  Google Scholar 

  33. Leiper JB, Aulin KP, Soderlund K. Improved gastric emptying rate in humans of a unique glucose polymer with gel-forming properties. Scand J Gastroenterol. 2000;35(11):1143–9.

    Article  CAS  PubMed  Google Scholar 

  34. Piehl Aulin K, Soderlund K, Hultman E. Muscle glycogen resynthesis rate in humans after supplementation of drinks containing carbohydrates with low and high molecular masses. Eur J Appl Physiol. 2000; 81(4):346–51.

    Article  CAS  PubMed  Google Scholar 

  35. Rowlands DS, Clarke J. Lower oxidation of a high molecular weight glucose polymer vs. glucose during cycling. Appl Physiol Nutr Metab. 2011;36(2):298–306.

    Article  CAS  PubMed  Google Scholar 

  36. Rowlands DS, Wallis GA, Shaw C, Jentjens RL, Jeukendrup AE. Glucose polymer molecular weight does not affect exogenous carbohydrate oxidation. Med Sci Sports Exerc. 2005;37(9):1510–6.

    Article  CAS  PubMed  Google Scholar 

  37. Ivy JL, Katz AL, Cutler CL, Sherman WM, Coyle EF. Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion. J Appl Physiol. 1988;64(4):1480–5.

    CAS  PubMed  Google Scholar 

  38. Garetto LP, Richter EA, Goodman MN, Ruderman NB. Enhanced muscle glucose metabolism after exercise in the rat: the two phases. Am J Physiol. 1984;246(6 Pt 1):E471–5.

    CAS  PubMed  Google Scholar 

  39. Miller SL, Tipton KD, Chinkes DL, Wolf SE, Wolfe RR. Independent and combined effects of amino acids and glucose after resistance exercise. Med Sci Sports Exerc. 2003;35(3):449–55.

    Article  CAS  PubMed  Google Scholar 

  40. Williams MH. The ergogenic edge. Champaign, IL: Human kinetics; 1998.

    Google Scholar 

  41. Blomstrand E, Celsing F, Newsholme EA. Changes in plasma concentrations of aromatic and branched-chain amino acids during sustained exercise in man and their possible role in fatigue. Acta Physiol Scand. 1988;133(1):115–21.

    Article  CAS  PubMed  Google Scholar 

  42. Castell LM, Yamamoto T, Phoenix J, Newsholme EA. The role of tryptophan in fatigue in different conditions of stress. Adv Exp Med Biol. 1999;467:697–704.

    Article  CAS  PubMed  Google Scholar 

  43. Davis JM, Bailey SP, Woods JA, Galiano FJ, Hamilton MT, Bartoli WP. Effects of carbohydrate feedings on plasma free tryptophan and branched-chain amino acids during prolonged cycling. Eur J Appl Physiol Occup Physiol. 1992;65(6):513–9.

    Article  CAS  PubMed  Google Scholar 

  44. Hassmen P, Blomstrand E, Ekblom B, Newsholme EA. Branched-chain amino acid supplementation during 30-km competitive run: mood and cognitive performance. Nutrition. 1994;10(5):405–10.

    CAS  PubMed  Google Scholar 

  45. Tanaka H, West KA, Duncan GE, Bassett Jr DR. Changes in plasma tryptophan/branched chain amino acid ratio in responses to training volume variation. Int J Sports Med. 1997;18(4):270–5.

    Article  CAS  PubMed  Google Scholar 

  46. Talbott SM, Hughes K. The health professionals guide to dietary supplements. Philadelphia: Lippincott, William & Wilkens; 2007.

    Google Scholar 

  47. Gastmann UA, Lehmann MJ. Overtraining and the BCAA hypothesis. Med Sci Sports Exerc. 1998;30(7):1173–8.

    Article  CAS  PubMed  Google Scholar 

  48. van Hall G, Raaymakers JS, Saris WH, Wagenmakers AJ. Ingestion of branched-chain amino acids and tryptophan during sustained exercise in man: failure to affect performance. J Physiol. 1995;486(Pt 3):789–94.

    Article  PubMed Central  PubMed  Google Scholar 

  49. Costill DL, Dalsky GP, Fink WJ. Effects of caffeine ingestion on metabolism and exercise performance. Med Sci Sports. 1978;10(3):155–8.

    CAS  PubMed  Google Scholar 

  50. Erickson MA, Schwarzkopf RJ, McKenzie RD. Effects of caffeine, fructose, and glucose ingestion on muscle glycogen utilization during exercise. Med Sci Sports Exerc. 1987;19(6):579–83.

    Article  CAS  PubMed  Google Scholar 

  51. Spriet LL, MacLean DA, Dyck DJ, Hultman E, Cederblad G, Graham TE. Caffeine ingestion and muscle metabolism during prolonged exercise in humans. Am J Physiol. 1992;262(6 Pt 1):E891–8.

    CAS  PubMed  Google Scholar 

  52. Schneiker KT, Bishop D, Dawson B, Hackett LP. Effects of caffeine on prolonged intermittent-sprint ability in team-sport athletes. Med Sci Sports Exerc. 2006;38(3):578–85.

    Article  CAS  PubMed  Google Scholar 

  53. Namdar M, Koepfli P, Grathwohl R, Siegrist PT, Klainguti M, Schepis T, et al. Caffeine decreases exercise-induced myocardial flow reserve. J Am Coll Cardiol. 2006;47(2):405–10.

    Article  CAS  PubMed  Google Scholar 

  54. Killer SC, Blannin AK, Jeukendrup AE. No evidence of dehydration with moderate daily coffee intake: a counterbalanced cross-over study in a free-living population. PLoS One. 2014;9(1), e84154.

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  55. Jimenez C, Melin B, Koulmann N, Allevard AM, Launay JC, Savourey G. Plasma volume changes during and after acute variations of body hydration level in humans. Eur J Appl Physiol Occup Physiol. 1999;80(1):1–8.

    Article  CAS  PubMed  Google Scholar 

  56. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc. 1999;99(2):207–12.

    Article  CAS  PubMed  Google Scholar 

  57. Lyons TP, Riedesel ML, Meuli LE, Chick TW. Effects of glycerol-induced hyperhydration prior to exercise in the heat on sweating and core temperature. Med Sci Sports Exerc. 1990;22(4):477–83.

    Article  CAS  PubMed  Google Scholar 

  58. Montner P, Stark DM, Riedesel ML, Murata G, Robergs R, Timms M, et al. Pre-exercise glycerol hydration improves cycling endurance time. Int J Sports Med. 1996;17(1):27–33.

    Article  CAS  PubMed  Google Scholar 

  59. Arnall DA, Goforth Jr HW. Failure to reduce body water loss in cold-water immersion by glycerol ingestion. Undersea Hyperb Med. 1993;20(4):309–20.

    CAS  PubMed  Google Scholar 

  60. Earnest CP. Effect of acute creatine monohydrate ingestion on anaerobic capacity. Kinesiology. 1997;141.

    Google Scholar 

  61. Earnest CP, Almada AL, Mitchell TL. Effect of creatine monohydrate ingestion on intermediate length anaerobic treadmill running to exhaustion. J Strength Cond Res. 1997;4:234–8.

    Google Scholar 

  62. Williams MH, Kreider R, Branch JD. Creatine: the power supplement (p 15). Champaign, IL: Human Kinetics; 1999.

    Google Scholar 

  63. Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci. 1992;83(3):367–74.

    Article  CAS  PubMed  Google Scholar 

  64. Smith JC, Stephens DP, Hall EL, Jackson AW, Earnest CP. Effect of oral creatine ingestion on parameters of the work rate-time relationship and time to exhaustion in high-intensity cycling. Eur J Appl Physiol Occup Physiol. 1998;77(4):360–5.

    Article  CAS  PubMed  Google Scholar 

  65. Blumenthal M, Busse WR, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS, editors. The complete commission E monographs: therapeutic guide to herbal medicines. Boston, MA: Integrative Medicine Communications; 1998.

    Google Scholar 

  66. Stout J, Eckerson J, Ebersole K, Moore G, Perry S, Housh T, et al. Effect of creatine loading on neuromuscular fatigue threshold. J Appl Physiol. 2000;88(1):109–12.

    CAS  PubMed  Google Scholar 

  67. Bangsbo J, Gollnick PD, Graham TE, Juel C, Kiens B, Mizuno M, et al. Anaerobic energy production and O2 deficit-debt relationship during exhaustive exercise in humans. J Physiol. 1990;422:539–59.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  68. Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis. Biochem J. 1992;281(Pt 1):21–40.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  69. Cade R, Conte M, Zauner C, Mars D, Peterson J, Lunne D, et al. Effects of phosphate loading on 2,3-diphosphoglycerate and maximal oxygen uptake. Med Sci Sports Exerc. 1984;16(3):263–8.

    Article  CAS  PubMed  Google Scholar 

  70. Hord NG, Tang Y, Bryan NS. Food sources of nitrates and nitrites: the physiologic context for potential health benefits. Am J Clin Nutr. 2009;90(1):1–10.

    Article  CAS  PubMed  Google Scholar 

  71. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, et al. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension. 2008;51(3):784–90.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  72. Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH, et al. Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circ Res. 2007;100(5):654–61.

    Article  CAS  PubMed  Google Scholar 

  73. Stamler JS, Meissner G. Physiology of nitric oxide in skeletal muscle. Physiol Rev. 2001;81(1):209–37.

    CAS  PubMed  Google Scholar 

  74. Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, Dimenna FJ, Wilkerson DP, et al. Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol. 2009;107(4):1144–55.

    Article  CAS  PubMed  Google Scholar 

  75. Earnest CP, Johannsen NM, Swift DL, Gillison FB, Mikus CR, Lucia A, et al. Aerobic and strength training in concomitant metabolic syndrome and type 2 diabetes. Med Sci Sports Exerc. 2014;46(7):1293–301.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  76. Larsen FJ, Weitzberg E, Lundberg JO, Ekblom B. Effects of dietary nitrate on oxygen cost during exercise. Acta Physiol. 2007;191(1):59–66.

    Article  CAS  Google Scholar 

  77. Santalla A, Earnest CP, Marroyo JA, Lucia A. The Tour de France: an updated physiological review. Int J Sports Physiol Perform. 2012;7(3):200–9.

    PubMed  Google Scholar 

  78. Cermak NM, Gibala MJ, van Loon LJ. Nitrate supplementation’s improvement of 10-km time-trial performance in trained cyclists. Int J Sport Nutr Exerc Metab. 2012;22(1):64–71.

    CAS  PubMed  Google Scholar 

  79. Bond H, Morton L, Braakhuis AJ. Dietary nitrate supplementation improves rowing performance in well-trained rowers. Int J Sport Nutr Exerc Metab. 2012;22(4):251–6.

    CAS  PubMed  Google Scholar 

  80. Murphy M, Eliot K, Heuertz RM, Weiss E. Whole beetroot consumption acutely improves running performance. J Acad Nutr Diet. 2012;112(4):548–52.

    Article  PubMed  Google Scholar 

  81. Bescos R, Ferrer-Roca V, Galilea PA, Roig A, Drobnic F, Sureda A, et al. Sodium nitrate supplementation does not enhance performance of endurance athletes. Med Sci Sports Exerc. 2012;44(12):2400–9.

    Article  CAS  PubMed  Google Scholar 

  82. Peacock O, Tjonna AE, James P, Wisloff U, Welde B, Bohlke N, et al. Dietary nitrate does not enhance running performance in elite cross-country skiers. Med Sci Sports Exerc. 2012;44(11):2213–9.

    Article  CAS  PubMed  Google Scholar 

  83. Wilkerson DP, Hayward GM, Bailey SJ, Vanhatalo A, Blackwell JR, Jones AM. Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists. Eur J Appl Physiol. 2012;112(12):4127–34.

    Article  CAS  PubMed  Google Scholar 

  84. Jensen L, Bangsbo J, Hellsten Y. Effect of high intensity training on capillarization and presence of angiogenic factors in human skeletal muscle. J Physiol. 2004;557(Pt 2):571–82.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  85. McConell GK, Bradley SJ, Stephens TJ, Canny BJ, Kingwell BA, Lee-Young RS. Skeletal muscle nNOS mu protein content is increased by exercise training in humans. Am J Physiol Regul Integr Comp Physiol. 2007;293(2):R821–8.

    Article  CAS  PubMed  Google Scholar 

  86. Poveda JJ, Riestra A, Salas E, Cagigas ML, Lopez-Somoza C, Amado JA, et al. Contribution of nitric oxide to exercise-induced changes in healthy volunteers: effects of acute exercise and long-term physical training. Eur J Clin Invest. 1997;27(11):967–71.

    Article  CAS  PubMed  Google Scholar 

  87. Mackinnon LT. Exercise and natural killer cells. What is the relationship? Sports Med. 1989;7(3):141–9.

    Article  CAS  PubMed  Google Scholar 

  88. McCarthy DA, Dale MM. The leucocytosis of exercise. A review and model. Sports Med. 1988;6(6):333–63.

    Article  CAS  PubMed  Google Scholar 

  89. Brahmi Z, Bray RA, Abrams SI. Evidence for an early calcium-independent event in the activation of the human natural killer cell cytolytic mechanism. J Immunol. 1985;135(6):4108–13.

    CAS  PubMed  Google Scholar 

  90. Berning JR. Energy intake, diet and muscle wasting. In: Kreider RB, Fry AC, O’Toole ML, editors. Overtraining in sport. Champaign, IL: Human Kinetics; 1998.

    Google Scholar 

  91. Haff GG, Lehmkuhl MJ, McCoy LB, Stone MH. Carbohydrate supplementation and resistance training. J Strength Cond Res. 2003;17(1):187–96.

    PubMed  Google Scholar 

  92. Flakoll PJ, Judy T, Flinn K, Carr C, Flinn S. Postexercise protein supplementation improves health and muscle soreness during basic military training in Marine recruits. J Appl Physiol. 2004;96(3):951–6.

    Article  PubMed  Google Scholar 

  93. Buckley JD, Abbott MJ, Brinkworth GD, Whyte PB. Bovine colostrum supplementation during endurance running training improves recovery, but not performance. J Sci Med Sport. 2002;5(2):65–79.

    Article  CAS  PubMed  Google Scholar 

  94. Buckley JD. Bovine colostrum: Does it improve athletic performance? Nutrition. 2002;18(9):776–7.

    Article  PubMed  Google Scholar 

  95. Brinkworth GD, Buckley JD, Bourdon PC, Gulbin JP, David A. Oral bovine colostrum supplementation enhances buffer capacity but not rowing performance in elite female rowers. Int J Sport Nutr Exerc Metab. 2002;12(3):349–65.

    PubMed  Google Scholar 

  96. Bolke E, Jehle PM, Hausmann F, Daubler A, Wiedeck H, Steinbach G, et al. Preoperative oral application of immunoglobulin-enriched colostrum milk and mediator response during abdominal surgery. Shock. 2002;17(1):9–12.

    Article  PubMed  Google Scholar 

  97. Khan Z, Macdonald C, Wicks AC, Holt MP, Floyd D, Ghosh S, et al. Use of the ‘nutriceutical’, bovine colostrum, for the treatment of distal colitis: results from an initial study. Aliment Pharmacol Ther. 2002;16(11):1917–22.

    Article  CAS  PubMed  Google Scholar 

  98. Playford RJ, MacDonald CE, Calnan DP, Floyd DN, Podas T, Johnson W, et al. Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability. Clin Sci. 2001;100(6):627–33.

    Article  CAS  PubMed  Google Scholar 

  99. Ardawi MS, Newsholme EA. Metabolism in lymphocytes and its importance in the immune response. Essays Biochem. 1985;21:1–44.

    CAS  PubMed  Google Scholar 

  100. Ardawi MS, Newsholme EA. Glutamine metabolism in lymphocytes of the rat. Biochem J. 1983;212(3):835–42.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  101. Carli F, Webster J, Ramachandra V, Pearson M, Read M, Ford GC, et al. Aspects of protein metabolism after elective surgery in patients receiving constant nutritional support. Clin Sci. 1990;78(6):621–8.

    Article  CAS  PubMed  Google Scholar 

  102. Vukovich MD, Sharp RL, Kesl LD, Schaulis DL, King DS. Effects of a low-dose amino acid supplement on adaptations to cycling training in untrained individuals. Int J Sport Nutr. 1997;7(4):298–309.

    CAS  PubMed  Google Scholar 

  103. Williams JZ, Abumrad N, Barbul A. Effect of a specialized amino acid mixture on human collagen deposition. Ann Surg. 2002;236(3):369–74. discussion 74–5.

    Article  PubMed Central  PubMed  Google Scholar 

  104. Castell LM, Poortmans JR, Newsholme EA. Does glutamine have a role in reducing infections in athletes? Eur J Appl Physiol Occup Physiol. 1996; 73(5):488–90.

    Article  CAS  PubMed  Google Scholar 

  105. Barbosa E, Moreira EA, Goes JE, Faintuch J. Pilot study with a glutamine-supplemented enteral formula in critically ill infants. Revista do Hospital das Clinicas. 1999;54(1):21–4.

    Article  CAS  PubMed  Google Scholar 

  106. des Robert C, Le Bacquer O, Piloquet H, Roze JC, Darmaun D. Acute effects of intravenous glutamine supplementation on protein metabolism in very low birth weight infants: a stable isotope study. Pediatr Res. 2002;51(1):87–93.

    Article  CAS  PubMed  Google Scholar 

  107. Yoshida S, Kaibara A, Ishibashi N, Shirouzu K. Glutamine supplementation in cancer patients. Nutrition. 2001;17(9):766–8.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Woodbolt International, Bryan, TX, USA

    Conrad P. Earnest PhD, FACSM

  2. Texas A&M University, College Station, TX, USA

    Conrad P. Earnest PhD, FACSM & Christopher Rasmussen MS, CSCS

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  1. Conrad P. Earnest PhD, FACSM
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  2. Christopher Rasmussen MS, CSCS
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Correspondence to Conrad P. Earnest PhD, FACSM .

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Editors and Affiliations

  1. Exercise Sport Nutrition Laboratory, Department of Health & Kinesiology, Texas A & M University, College Station, Texas, USA

    Mike Greenwood

  2. Biomedical and Lifestyle Diseases (BioLED) Unit, Institute of Sport, Exercise & Active Living, College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia

    Matthew B. Cooke

  3. The Center For Applied Health Sciences (CAHS), Stow, Ohio, USA

    Tim Ziegenfuss

  4. Nutrition & Applied Clinical Trials, QPS-MRA (Miami Research) & Athletics Department, Florida International University, Miami, Florida, USA

    Douglas S. Kalman

  5. Exercise & Sport Science Laboratory, Nova Southeastern University, Fort Lauderdale-Davie, Florida, USA

    Jose Antonio

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Earnest, C.P., Rasmussen, C. (2015). Nutritional Supplements for Endurance Athletes. In: Greenwood, M., Cooke, M., Ziegenfuss, T., Kalman, D., Antonio, J. (eds) Nutritional Supplements in Sports and Exercise. Springer, Cham. https://doi.org/10.1007/978-3-319-18230-8_11

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