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Role of Mucosal Healing

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Endoscopy in Inflammatory Bowel Disease

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Abstract

Mucosal healing (MH), defined by the complete endoscopic healing of all inflammatory lesions, has become a relevant measure of inflammatory bowel disease (IBD) status and an important treatment goal. Endoscopy is the gold standard to evaluate MH and treatment response. In this chapter we review the significance of MH in the two main types of IBD, ulcerative colitis (UC) and Crohn’s disease (CD), the various endoscopic scoring systems for each, and clinical applications of MH for the care of IBD patients.

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Acknowledgments

The authors would like to thank Dr. Douglas Hartman, MD, for providing histology images.

Financial Disclosures

Dr. Barrie—none

Dr. Regueiro—Abbvie, Janssen, UCB, Shire, Takeda

Author information

Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Arthur M. Barrie III MD, PhD

  2. Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh Medical Center, 200 Lothrop Street, C-Wing, Mezzanine, Pittsburgh, 15213, PA, USA

    Miguel Regueiro MD

Authors
  1. Arthur M. Barrie III MD, PhD
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  2. Miguel Regueiro MD
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Corresponding author

Correspondence to Miguel Regueiro MD .

Editor information

Editors and Affiliations

  1. Digestive Disease Institute, Virginia Mason Medical Center, Seattle, Washington, USA

    Richard Kozarek

  2. Digestive Disease Institute, Virginia Mason Medical Center, Seattle, Washington, USA

    Michael Chiorean

  3. Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA

    Michael Wallace

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© 2015 Springer International Publishing Switzerland

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Barrie, A.M., Regueiro, M. (2015). Role of Mucosal Healing. In: Kozarek, R., Chiorean, M., Wallace, M. (eds) Endoscopy in Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-11077-6_12

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  • DOI: https://doi.org/10.1007/978-3-319-11077-6_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-11076-9

  • Online ISBN: 978-3-319-11077-6

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