Abstract
Acquired thrombophilias are common—this chapter discusses PNH, Behcet’s disease, nephrotic syndrome, inflammatory bowel disease, and air travel. Acquired thrombophilias range from rare disorders such as Behçet’s disease to the very common initial presentation of malignancy. Acquired hypercoagulable states may present at any age. Patients with acquired disorders often present with a “flurry” of thromboses. While patients with congenital disorders may have two thromboses separated by years, the patient with an acquired thrombophilia may present with repeated thrombosis even on anticoagulant therapy. In some patients, thrombosis may be the first manifestation of the underlying disease. In many patients thrombosis is a well-recognized complication of the underlying disease.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Barbano B, Gigante A, Amoroso A, Cianci R. Thrombosis in nephrotic syndrome. Semin Thromb Hemost. 2013;39(5):469–76.
Cannegieter SC. Travel-related thrombosis. Best Pract Res Clin Haematol. 2012;25(3):345–50.
Hill A, Kelly RJ, Hillmen P. Thrombosis in paroxysmal nocturnal hemoglobinuria. Blood. 2013;121(25):4985–96.
Nguyen GC, Bernstein CN, Bitton A, Chan AK, Griffiths AM, Leontiadis GI, Geerts W, Bressler B, Butzner JD, Carrier M, Chande N, Marshall JK, Williams C, Kearon C. Consensus statements on the risk, prevention, and treatment of venous thromboembolism in inflammatory bowel disease: Canadian Association of Gastroenterology. Gastroenterology. 2014;146:835–848.e6.
Springer J, Villa-Forte A. Thrombosis in vasculitis. Curr Opin Rheumatol. 2013;25(1):19–25.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
DeLoughery, T.G. (2015). Acquired Thrombophilias. In: DeLoughery, T. (eds) Hemostasis and Thrombosis. Springer, Cham. https://doi.org/10.1007/978-3-319-09312-3_18
Download citation
DOI: https://doi.org/10.1007/978-3-319-09312-3_18
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-09311-6
Online ISBN: 978-3-319-09312-3
eBook Packages: MedicineMedicine (R0)