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Neuroimaging in PTSD and Relationship with Other Stress Disorders: Comparisons with Anxiety Disorders and Depression

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Comprehensive Guide to Post-Traumatic Stress Disorder

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Abstract

To review the neuroimaging in PTSD and its relationship with other stress disorders, in this chapter, the author mainly refers to the neuroimaging studies in other stress disorders such as panic disorder (PD), social anxiety disorder (social phobia: SAD), specific phobia (SP), generalized anxiety disorder (GAD), and major depressive disorder (MDD). This chapter will give the particulars of putative neuroanatomical models of these six stress disorders based on neuroimaging techniques such as mainly magnetic resonance imaging (MRI) and functional MRI (fMRI), respectively.

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Abbreviations

5-HT:

Serotonin

ACC:

Anterior cingulate gyrus

B:

Basal nucleus of amygdala

BDNF:

Brain-derived neurotrophic factor

BNST:

Bed nucleus of stria terminalis

BOLD:

Blood oxygenation level dependent

BP:

Blood pressure

CCK-4:

Cholecystokinin tetrapeptide

CE:

Central nucleus of amygdala

fMRI:

Functional MRI

GABA:

γ-Aminobutyric acid

GAD:

Generalized anxiety disorder

GC:

Glucocorticoid

HR:

Heart rate

ITC:

Intercalated cell masses in amygdala

LA:

Lateral nucleus of amygdala

LN:

Lateral nucleus

MDD:

Major depressive disorder

mPFC:

Medial prefrontal cortex

MRI:

Magnetic resonance imaging

NA:

Noradrenaline

OFC:

Orbitofrontal cortex

PD:

Panic disorder

PET:

Positron emission tomography

PN:

Paraventricular nucleus

PTSD:

Posttraumatic stress disorder

REM:

Rapid eye movement

Social phobia: SAD:

Social anxiety disorder

SP:

Specific phobia

SPECT:

Single-photon emission computed tomography (SPECT)

SSRI:

Selective serotonin reuptake inhibitors

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Authors and Affiliations

  1. Department of Psychiatry and Psychotherapy, Gifu University, Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan

    Toshiki Shioiri

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  1. Toshiki Shioiri
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Correspondence to Toshiki Shioiri .

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Editors and Affiliations

  1. Buckinghamshire New University, Uxbridge, Middlesex, United Kingdom

    Colin R. Martin

  2. Kings College, London, United Kingdom

    Victor R. Preedy

  3. University of Westminster, London, United Kingdom

    Vinood B. Patel

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Shioiri, T. (2015). Neuroimaging in PTSD and Relationship with Other Stress Disorders: Comparisons with Anxiety Disorders and Depression. In: Martin, C., Preedy, V., Patel, V. (eds) Comprehensive Guide to Post-Traumatic Stress Disorder. Springer, Cham. https://doi.org/10.1007/978-3-319-08613-2_85-1

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  • DOI: https://doi.org/10.1007/978-3-319-08613-2_85-1

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