Skip to main content

Statistical Considerations

  • Chapter
  • First Online:
Epidemiology of Human Congenital Malformations

Abstract

Statistical considerations include discussions of study power, of the significance of confounders and how adjustment for confounders are made, mass significance and the meaning of p values, lumping or splitting. A summery is given of the statistical methods used in the book.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Källén B. The problem of confounding in studies of the effect of maternal drug use on pregnancy outcome. Obstet Gynecol Int. 2012a. doi:10.1155/2012/148616.

    PubMed  Google Scholar 

  • Källén B. Chapter 26: Human studies – epidemiologic techniques in developmental and reproductive toxicology. In: Hood RD, editor. Developmental and reproductive toxicology. A practical approach. 3rd ed. Colchester: Informa Health Care; 2012b. p. 643–74.

    Google Scholar 

  • Källén K. Maternal smoking and congenital malformations. Fetal Matern Med Rev. 2002;13:63–86.

    Article  Google Scholar 

  • Mantel N, Haenszel W. Statistical aspects of the analyses of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22:719–48.

    PubMed  CAS  Google Scholar 

  • Robert E, Guibaud P. Maternal valproic acid and congenital neural tube defect. Lancet. 1982;ii:937.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Källén, B. (2014). Statistical Considerations. In: Epidemiology of Human Congenital Malformations. Springer, Cham. https://doi.org/10.1007/978-3-319-01472-2_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-01472-2_4

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-01471-5

  • Online ISBN: 978-3-319-01472-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics