Overview
Part of the book series: Journal of Neural Transmission. Supplementa (NEURALTRANS, volume 73)
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Table of contents (28 chapters)
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Birth of dopaminergic neurons
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SNc Dopaminergic neurons
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Death of SNc Dopaminergic neurons
Keywords
About this book
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.
Editors and Affiliations
Bibliographic Information
Book Title: Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra
Editors: Giuseppe Giovanni, Vincenzo Di Matteo, Ennio Esposito
Series Title: Journal of Neural Transmission. Supplementa
DOI: https://doi.org/10.1007/978-3-211-92660-4
Publisher: Springer Vienna
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag Vienna 2009
Hardcover ISBN: 978-3-211-92659-8Published: 28 September 2009
Softcover ISBN: 978-3-7091-1092-8Published: 14 March 2012
eBook ISBN: 978-3-211-92660-4Published: 02 September 2009
Series ISSN: 0303-6995
Edition Number: 1
Number of Pages: XI, 369
Additional Information: Special edition of Journal of Neural Transmission, Supplement 73
Topics: Neurology