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Maximizing the value of genomics in the drug discovery and development process

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Progress in Drug Research

Part of the book series: Progress in Drug Research ((PDR,volume 60))

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Summary

Genomics and all the associated technologies it has spawned have fundamentally changed the way research and development organizations carry out the work they do in the early stages of discovery. However, successful organizations must move from product concept through to registration as efficiently as possible. In order to achieve this, the early “basic” science must be combined with the clinical perspective from the start. Furthermore, since the genomics industry was first established in the early 1990s it has evolved from tool and data suppliers to drug development companies. It is therefore likely that we will see technology advances in genomics become more limited in the years ahead.

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Abbreviations

cDNA:

copy deoxyribonucleic acid

Cox2:

cyclooxygenase 2

DMOAD:

disease-modifying osteoarthritis drug

iNOS:

nitric oxide synthase

mRNA:

messenger ribonucleic acid

NCBI:

National Center for Biotechnology Information

OA:

osteoarthritis

SNP:

single nucleotide polymorphism

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© 2003 Springer Basel AG

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Spence, P. (2003). Maximizing the value of genomics in the drug discovery and development process. In: Jucker, E. (eds) Progress in Drug Research. Progress in Drug Research, vol 60. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8012-1_5

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  • DOI: https://doi.org/10.1007/978-3-0348-8012-1_5

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-9402-9

  • Online ISBN: 978-3-0348-8012-1

  • eBook Packages: Springer Book Archive

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