Abstract
Chapter 15 provides a detailed exploration of germ cell tumors. This chapter covers a range of tumor types, including germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, and teratoma. It offers insights into their definition, epidemiology, pathology, molecular genetics, etiology, and clinical presentation. It further addresses staging and classification, diagnostic procedures, and various treatment options and considerations. The critical aspects of recurrence, follow-up, and prognosis are also discussed. This chapter serves to facilitate a well-structured approach to understanding and managing these tumors in the field of surgical neuro-oncology.
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Bibliography
Jennings MT, Gelman R, Hochberg F. Intracranial germ cell tumors: natural history and pathogenesis. J Neurosurg. 1985;63(2):155–67.
Sato K, Takeuchi H, Kubota T. Pathology of intracranial germ cell tumors. Prog Neurol Surg. 2009;23:59–75.
Brandes AA, Pasetto LM, Monfardini S. The treatment of cranial germ cell tumours. Cancer Treat Rev. 2000;26(4):233–42.
Lo AC, Hodgson D, Dang J, Tyldesley S, Bouffet E, Bartels U, Cheng S, Hukin J, Bedard PL, Goddard K, Laperriere N. Intracranial germ cell tumors in adolescents and young adults: a 40-year multi-institutional review of outcomes. Int J Radiat Oncol Biol Phys. 2020;106(2):269–78.
Kyritsis AP. Management of primary intracranial germ cell tumors. J Neuro-Oncol. 2010;96(2):143–9.
Kurucu N, Akyüz C, Varan A, Zorlu F, Aydin B, Söylemezoglu F, Yalcin B, Kutluk T, Büyükpamukcus M. Primary intracranial germ cell tumors in children 36-year experience of a single center. J Cancer Res Ther. 2020;16(6):1459–65.
Sahay A, Epari S, Chinnaswamy G, Chatterjee A, Goda JS, Patil V, Moyiadi A, Shetty P, Singh V, Sahu A, Choudhary A, Janu A, Gupta T. Primary intracranial germ cell tumors: a study with an integrated clinicopathological approach. Neurol India. 2023;71(3):500–8.
Aoyama H. Radiation therapy for intracranial germ cell tumors. Prog Neurol Surg. 2009;23:96–105.
Khafaga Y, El Weshi A, Nazmy M, Hassounah M, Alshail E, Moussa E, Allam A, Alkofide A, Jamshed A, Elhusseiny G, Ezzat I, Jenkin D. Intracranial germ cell tumors: a single-institution experience. Ann Saudi Med. 2012;32(4):359–65.
Matsutani M. Pineal germ cell tumors. Prog Neurol Surg. 2009;23:76–85.
Bowzyk Al-Naeeb A, Murray M, Horan G, Harris F, Kortmann RD, Nicholson J, Ajithkumar T. Current management of intracranial germ cell tumours. Clin Oncol (R Coll Radiol). 2018;30(4):204–14.
Balmaceda C, Finlay J. Current advances in the diagnosis and management of intracranial germ cell tumors. Curr Neurol Neurosci Rep. 2004;4(3):253–62.
Kakkar A, Biswas A, Kalyani N, Chatterjee U, Suri V, Sharma MC, Goyal N, Sharma BS, Mallick S, Julka PK, Chinnaswamy G, Arora B, Sridhar E, Chatterjee S, Jalali R, Sarkar C. Intracranial germ cell tumors: a multi-institutional experience from three tertiary care centers in India. Childs Nerv Syst. 2016;32(11):2173–80.
Plant AS, Chi SN, Frazier L. Pediatric malignant germ cell tumors: a comparison of the neuro-oncology and solid tumor experience. Pediatr Blood Cancer. 2016;63(12):2086–95.
Osorio DS, Allen JC. Management of CNS germinoma. CNS Oncol. 2015;4(4):273–9.
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Atallah, O. et al. (2024). Germ Cell Tumors. In: Hoz, S.S., et al. Surgical Neuro-Oncology. Springer, Cham. https://doi.org/10.1007/978-3-031-53642-7_15
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DOI: https://doi.org/10.1007/978-3-031-53642-7_15
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