Abstract
This study introduces ternary oxide nanoparticles synthesized from a blend of plantain peel, guava leaves, and mushroom extracts, containing iron, silver, and vanadium. These nanoparticles, with an average diameter of 291.6 nm and a polydispersity index (PDI) of 0.137, exhibit characteristics suitable for drug delivery systems, potentially enhancing tuberculosis (TB) treatment outcomes. Their irregular morphology leads to aggregated formations, creating a porous structure ideal for drug loading and controlled release, which may improve therapeutic efficacy. The incorporation of silver oxide nanoparticles imparts antimicrobial properties, offering potential inhibition of Mycobacterium tuberculosis growth. This innovative approach, combining iron, silver, and vanadium oxides, presents promising avenues for TB treatment. Future research is imperative to validate the nanoparticles' effectiveness and safety, highlighting their potential in advancing TB treatment strategies and infectious disease management.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ifijen IH, Ikhuoria EU, Omorogbe SO, Anegbe B, Jonathan EM, Chikaodili DI (2023) Chemical, plant and microbial mediated synthesis of tin oxide nanoparticles: antimicrobial and anticancer potency. Braz J Chem Eng. https://doi.org/10.1007/s43153-023-00315-0
Maliki M, Ifijen IH, Ikhuoria EU et al (2022) Copper nanoparticles and their oxides: optical, anticancer and antibacterial properties. Int Nano Lett 12:379–398
Ifijen IH, Ikhuoria EU, Omorogbe SO, Otabor GO, Aigbodion AI, Ibrahim SD (2023) A review of P(St-MMA-AA) synthesis via emulsion polymerization, 3D P(St-MMA-AA) photonic crystal fabrication, and photonic application. In: TMS 2023 152nd annual meeting & exhibition supplemental proceedings. TMS 2023. The minerals, metals & materials society. Springer, Cham. https://doi.org/10.1007/978-3-031-22524-6_30.
Ikhuoria EU, Omorogbe SO, Sone BT, Maaza M (2018) Bioinspired shape controlled antiferromagnetic Co3O4 with prism like-anchored octahedron morphology: a facile green synthesis using Manihot esculenta Crantz extract. Sci Technol Mater Sci Technol Mater 30(2):92-90
Omorogbe SO, Aigbodion AI, Ifijen HI, Simo A, Ogbeide-Ihama NL, Ikhuoria EU (2020) Low-temperature synthesis of superparamagnetic Fe3O4 morphologies tuned using oleic acid as crystal growth modifiers. In: TMS 2020 149th annual meeting & exhibition supplemental proceedings. The minerals, metals & materials society. Springer, Cham. https://doi.org/10.1007/978-3-030-36296-6_58
Omorogbe SO, Ikhuoria EU, Igiehon LI, Agbonlahor GO, Ifijen IH, Aigbodion AI (2017) Characterization of sulphated cellulose nanocrystals as stabilizer for magnetite nanoparticles synthesis with improved magnetic properties. Nigerian J Mater Sci Eng 7(2):23–31
Ifijen IH, Udokpoh NU, Maliki M, Ikhuoria EU, Obazee EO (2023) A review of nanovanadium compounds for cancer cell therapy. In: TMS 2023 152nd annual meeting & exhibition supplemental proceedings. The minerals, metals & materials society. Springer, Cham. https://doi.org/10.1007/978-3-031-22524-6_59
Mokobia KE, Ifijen IH, Ikhuoria EU (2023) ZnO-NPs-coated implants with osteogenic properties for enhanced Osseointegration. In: TMS 2023 152nd annual meeting & exhibition supplemental proceedings. The minerals, metals & materials society. Springer, Cham. https://doi.org/10.1007/978-3-031-22524-6_27
Ifijen IH, Maliki M, Odiachi IJ, Omoruyi IC, Aigbodion AI, Ikhuoria EU (2022) Performance of metallic-based nanomaterials doped with strontium in biomedical and supercapacitor electrodes: a review. Biomed Mater Devices. https://doi.org/10.1007/s44174-022-00006-3
Udokpoh NU, Jacob JN, Archibong UD, Onaiwu GE, Ifijen IH (2023) Utilizations of graphene-based nanomaterials for the detection and treatment of Mycobacterium Tuberculosis. In: TMS 2023 152nd annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham. https://doi.org/10.1007/978-3-031-22524-6_5
Abebe B, Murthy HCA, Zerefa E, Adimasu Y (2020) PVA assisted ZnO based mesoporous ternary metal oxides nanomaterials: synthesis, optimization, and evaluation of antibacterial activity. Mater Res Express 7:045011
Ifijen IH, Ikhuoria EU, Omorogbe SO et al (2023) Chemical, plant and microbial mediated synthesis of tin oxide nanoparticles: antimicrobial and anticancer potency. Braz J Chem Eng. https://doi.org/10.1007/s43153-023-00315-0
Javed R, Zia M, Naz S et al (2020) Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects. J Nanobiotechnol 18:172. https://doi.org/10.1186/s12951-020-00704-4
Gentili D, Ori G (2022) Reversible assembly of nanoparticles: theory, strategies, and computational simulations. Nanoscale 14(36):14385–14432. https://doi.org/10.1039/D2NR02640F
Bertolucci E, Galletti AMR, Antonetti C, Marracci M, Tellini B, Piccinelli F, Visone C (2015) Chemical and magnetic properties characterization of magnetic nanoparticles. In: 2015 IEEE international instrumentation and measurement technology conference (I2MTC) proceedings, pp 1492–1496. IEEE. https://doi.org/10.1109/i2mtc.2015.7151498
Wu Y, Gao G, Wu G (2015) Self-assembled three-dimensional hierarchical porous V2O5/graphene hybrid aerogels for supercapacitors with high energy density and long cycle life. J Mater Chem A 3:1828–1832. https://doi.org/10.1039/C4TA05537C
Li R, Chen Z, Ren N, Wang Y, Wang Y, Yu F (2019) Biosynthesis of silver oxide nanoparticles and their photocatalytic and antimicrobial activity evaluation for wound healing applications in nursing care. J Photochem Photobiol, B 199:111593. https://doi.org/10.1016/j.jphotobiol.2019.111593
Sutrisno L, Ariga K (2023) Nanoarchitectonics with engineered pores for cancer therapy. NPG Asia Mater 15(21). https://doi.org/10.1038/s41427-023-00469-w
Kerantzas CA, Jacobs WR Jr (2017) Origins of combination therapy for tuberculosis: lessons for future antimicrobial development and application. mBio 8(2):e01586–16. https://doi.org/10.1128/mBio.01586-16. PMID: 28292983; PMCID: PMC5350467
Campbell S, Smeets N (2019) Drug delivery: localized and systemic therapeutic strategies with polymer systems. In: Jafar Mazumder M, Sheardown H, Al-Ahmed A (eds) Functional polymers. Polymers and polymeric composites: a reference series. Springer, Cham. https://doi.org/10.1007/978-3-319-95987-0_32
Li J, Mooney DJ (2016) Designing hydrogels for controlled drug delivery. Nat Rev Mater 1(12):16071. https://doi.org/10.1038/natrevmats.2016.71
Uskokovic V (2015) Nanostructured platforms for the sustained and local delivery of antibiotics in the treatment of osteomyelitis. Crit Rev Ther Drug Carrier Syst 32(1):1–59. https://doi.org/10.1615/critrevtherdrugcarriersyst.2014010920
Tăbăran AF, Matea CT, Mocan T, Tăbăran A, Mihaiu M, Iancu C, Mocan L (2020) Silver nanoparticles for the therapy of tuberculosis. Int J Nanomed 15:2231–2258. https://doi.org/10.2147/IJN.S241183
Yin IX, Zhang J, Zhao IS, Mei ML, Li Q, Chu CH (2020) The antibacterial mechanism of silver nanoparticles and its application in dentistry. Int J Nanomed 15:2555–2562. https://doi.org/10.2147/IJN.S246764
Montiel Schneider MG, MartÃn MJ, Otarola J, Vakarelska E, Simeonov V, Lassalle V, Nedyalkova M (2022) Biomedical applications of iron oxide nanoparticles: current insights progress and perspectives. Pharmaceutics 14(1):204. https://doi.org/10.3390/pharmaceutics14010204
Wang J, Zhou H, Guo G, Cheng T, Peng X, Mao X, Zhang X et al (2017) A functionalized surface modification with vanadium nanoparticles of various valences against implant-associated bloodstream infection. Int J Nanomed 12, 3121–3136. https://doi.org/10.2147/IJN.S129459
Acknowledgements
The authors express heartfelt gratitude to TETFUND for their generous research funding, which played a pivotal role in the successful completion of their study. This support enabled crucial experiments, access to essential resources, and the presentation of findings at conferences, elevating the overall quality and impact of the research. TETFUND’s commitment to fostering research excellence and their significant contribution to the academic community is deeply appreciated. Their support not only advanced the authors' careers but also contributed to the progress of knowledge in Nanotechnology. The authors extend their wholehearted thanks to TETFUND for their unwavering support and acknowledge the valuable opportunity provided by their research funding.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Minerals, Metals & Materials Society
About this paper
Cite this paper
Uwidia, I.E., Ikhuoria, E.U., Okojie, R.O., Ifijen, I.H., Chikaodili, I.D. (2024). Synthesis of Ternary Oxide Nanoparticles of Iron, Silver, and Vanadium from Blended Extracts for Potential Tuberculosis Treatment. In: TMS 2024 153rd Annual Meeting & Exhibition Supplemental Proceedings. TMS 2024. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-031-50349-8_118
Download citation
DOI: https://doi.org/10.1007/978-3-031-50349-8_118
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-50348-1
Online ISBN: 978-3-031-50349-8
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)