Zusammenfassung
PET/CT hat aufgrund verbesserter Geräteerfassungsmerkmale die diagnostische Bewertung von Phäochromozytomen und Paragangliomen verbessert. PET-Radiotracer für diese Tumoren bewerten häufig die Expression von Somatostatinrezeptoren, Aminosäuretransportsystemen oder den Glukosestoffwechsel. Die Sensitivität ist im Vergleich zu MIBG verbessert, einschließlich bei Tumoren mit SDHx-Genmutationen. Falsch positive Ergebnisse können Läsionen von anderen Tumoren, Meningiomen, entzündlichen Krankheiten oder physiologischer Pankreas-Aufnahme einschließen. Falsch negative Ergebnisse können aufgrund von Harn-Radiotracer-Ausscheidung oder der Verwendung von kalten Somatostatinanaloga zur Tumorkontrolle auftreten.
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Coura-Filho, G.B., Torres Silva de Oliveira, M., Morais de Campos, A.L. (2024). Positronen-Emissionstomographie bei Phäochromozytomen und Paragangliomen. In: Nuklearmedizin bei endokrinen Erkrankungen. Springer, Cham. https://doi.org/10.1007/978-3-031-47988-5_27
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