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Overview of Inpatient Management of Hypertriglyceridemia Associated Acute Pancreatitis in Patients with Diabetes Mellitus

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Diabetes Management in Hospitalized Patients

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Abstract

Dyslipidemia associated with diabetes mellitus (DM) has been identified as a risk factor for acute pancreatitis. Hypertriglyceridemia is often seen in patients with diabetes mellitus and is a known cause of acute pancreatitis. In acute pancreatitis caused by hypertriglyceridemia, insulin has been found to be the most effective therapy due to its ability for dose adjustment and its anti-inflammatory properties. It has been a topic of discussion whether to use low rates of intravenous (IV) insulin and dextrose fluids versus higher rates for hypertriglyceridemia-induced acute pancreatitis. We will also discuss evidence on acute pancreatitis risks associated with certain DM medications. This chapter provides an overview of the inpatient care of those with diabetes mellitus and acute pancreatitis.

We thank Vishnu Priya Pulipati for their expert suggestions and involvement in the critical review of the chapter.

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Benyaminov, F., Sinha, A. (2023). Overview of Inpatient Management of Hypertriglyceridemia Associated Acute Pancreatitis in Patients with Diabetes Mellitus. In: Schulman-Rosenbaum, R.C. (eds) Diabetes Management in Hospitalized Patients. Contemporary Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-031-44648-1_14

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