Abstract
The shape of the posterior eyeball is a crucial factor in many clinical applications, such as myopia prevention, surgical planning, and disease screening. However, current shape representations are limited by their low resolution or small field of view, providing insufficient information for surgeons to make accurate decisions. This paper proposes a novel task of reconstructing complete 3D posterior shapes based on small-FOV OCT images and introduces a novel Posterior Eyeball Shape Network (PESNet) to accomplish this task. The proposed PESNet is designed with dual branches that incorporate anatomical information of the eyeball as guidance. To capture more detailed information, we introduce a Polar Voxelization Block (PVB) that transfers sparse input point clouds to a dense representation. Furthermore, we propose a Radius-wise Fusion Block (RFB) that fuses correlative hierarchical features from the two branches. Our qualitative results indicate that PESNet provides a well-represented complete posterior eyeball shape with a chamfer distance of 9.52, SSIM of 0.78, and Density of 0.013 on the self-made posterior ocular shape dataset. We also demonstrate the effectiveness of our model by testing it on patients’ data. Overall, our proposed PESNet offers a significant improvement over existing methods in accurately reconstructing the complete 3D posterior eyeball shape. This achievement has important implications for clinical applications.
J. Zhang and Y. Hu—Co-first authors.
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References
Alamouti, B., Funk, J.: Retinal thickness decreases with age: an oct study. Br. J. Ophthalmol. 87(7), 899–901 (2003)
Atchison, D.A., et al.: Eye shape in emmetropia and myopia. Investig. Ophthalmol. Vis. Sci. 45(10), 3380–3386 (2004)
Belghith, A., et al.: Structural change can be detected in advanced-glaucoma eyes. Investig. Ophthalmol. Vis. Sci. 57(9), OCT511–OCT518 (2016)
Bongratz, F., Rickmann, A.M., Pölsterl, S., Wachinger, C.: Vox2cortex: fast explicit reconstruction of cortical surfaces from 3D MRI scans with geometric deep neural networks. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pp. 20773–20783 (2022)
Brennan, N.A., Toubouti, Y.M., Cheng, X., Bullimore, M.A.: Efficacy in myopia control. Prog. Retin. Eye Res. 83, 100923 (2021)
Ciller, C., et al.: Multi-channel MRI segmentation of eye structures and tumors using patient-specific features. PLoS ONE 12(3), e0173900 (2017)
Ciller, C., et al.: Automatic segmentation of the eye in 3D magnetic resonance imaging: a novel statistical shape model for treatment planning of retinoblastoma. Int. J. Radiat. Oncol. Biol. Phys. 92(4), 794–802 (2015)
Guo, X., et al.: Three-dimensional eye shape, myopic maculopathy, and visual acuity: the Zhongshan ophthalmic center-brien holden vision institute high myopia cohort study. Ophthalmology 124(5), 679–687 (2017)
He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)
Ishii, K., Iwata, H., Oshika, T.: Quantitative evaluation of changes in eyeball shape in emmetropization and myopic changes based on elliptic fourier descriptors. Investig. Ophthalmol. Vis. Sci. 52(12), 8585–8591 (2011)
Johnson, J., Alahi, A., Fei-Fei, L.: Perceptual losses for real-time style transfer and super-resolution. In: Leibe, B., Matas, J., Sebe, N., Welling, M. (eds.) ECCV 2016. LNCS, vol. 9906, pp. 694–711. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46475-6_43
Kim, Y.C., Moon, J.S., Park, H.Y.L., Park, C.K.: Three dimensional evaluation of posterior pole and optic nerve head in tilted disc. Sci. Rep. 8(1), 1–11 (2018)
Kuo, A.N., et al.: Correction of ocular shape in retinal optical coherence tomography and effect on current clinical measures. Am. J. Ophthalmol. 156(2), 304–311 (2013)
Leshno, A., Mezad-Koursh, D., Ziv-Baran, T., Stolovitch, C.: A paired comparison study on refractive changes after strabismus surgery. J. Am. Assoc. Pediatr. Ophthalmol. Strabismus 21(6), 460–462 (2017)
Liu, J., et al.: Planemvs: 3D plane reconstruction from multi-view stereo. In: Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), pp. 8665–8675 (2022)
Mildenhall, B., Srinivasan, P.P., Tancik, M., Barron, J.T., Ramamoorthi, R., Ng, R.: NERF: representing scenes as neural radiance fields for view synthesis. Commun. ACM 65(1), 99–106 (2021)
Miyake, M., et al.: Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. PLoS ONE 9(9), e107923 (2014)
Moriyama, M., et al.: Topographic analyses of shape of eyes with pathologic myopia by high-resolution three-dimensional magnetic resonance imaging. Ophthalmology 118(8), 1626–1637 (2011)
Palchunova, K., et al.: Precise retinal shape measurement by alignment error and eye model calibration. Opt. Rev. 29(3), 188–196 (2022)
Park, Y., Kim, Y.C., Ahn, Y.J., Park, S.H., Shin, S.Y.: Morphological change of the posterior pole following the horizontal strabismus surgery with swept source optical coherence tomography. Sci. Rep. 11(1), 1–11 (2021)
Qi, C.R., Su, H., Mo, K., Guibas, L.J.: Pointnet: deep learning on point sets for 3D classification and segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 652–660 (2017)
Rozema, J., Dankert, S., Iribarren, R., Lanca, C., Saw, S.M.: Axial growth and lens power loss at myopia onset in Singaporean children. Investig. Ophthalmol. Vis. Sci. 60(8), 3091–3099 (2019)
Singh, K.D., Logan, N.S., Gilmartin, B.: Three-dimensional modeling of the human eye based on magnetic resonance imaging. Investig. Ophthalmol. Vis. Sci. 47(6), 2272–2279 (2006)
Sun, L., Shao, W., Zhang, D., Liu, M.: Anatomical attention guided deep networks for ROI segmentation of brain MR images. IEEE Trans. Med. Imaging 39(6), 2000–2012 (2019)
Tatewaki, Y., et al.: Morphological prediction of glaucoma by quantitative analyses of ocular shape and volume using 3-dimensional T2-weighted MR images. Sci. Rep. 9(1), 15148 (2019)
Verkicharla, P.K., Mathur, A., Mallen, E.A., Pope, J.M., Atchison, D.A.: Eye shape and retinal shape, and their relation to peripheral refraction. Ophthalmic Physiol. Opt. 32(3), 184–199 (2012)
Wang, Y.X., Panda-Jonas, S., Jonas, J.B.: Optic nerve head anatomy in myopia and glaucoma, including parapapillary zones alpha, beta, gamma and delta: histology and clinical features. Prog. Retin. Eye Res. 83, 100933 (2021)
Xiang, P., et al.: Snowflake point deconvolution for point cloud completion and generation with skip-transformer. IEEE Trans. Pattern Anal. Mach. Intell. 45(5), 6320–6338 (2022)
Acknowledgment
This work was supported in part by General Program of National Natural Science Foundation of China (82272086 and 82102189), Guangdong Basic and Applied Basic Research Foundation (2021A1515012195), Shenzhen Stable Support Plan Program (20220815111736001 and 20200925174052004), and Agency for Science, Technology and Research (A*STAR) Advanced Manufacturing and Engineering (AME) Programmatic Fund (A20H4b0141) and Central Research Fund (CRF).
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Zhang, J. et al. (2023). Polar Eyeball Shape Net for 3D Posterior Ocular Shape Representation. In: Greenspan, H., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2023. MICCAI 2023. Lecture Notes in Computer Science, vol 14225. Springer, Cham. https://doi.org/10.1007/978-3-031-43987-2_18
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