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Abstract

In most cases, conservative therapy should be the first line treatment for those with anal incontinence. In very selected patients, such as women in the post-partum period who have suffered an obstetric anal sphincter injury (OASI) and have a wound infection or breakdown, anal sphincter repair may be offered. There is evidence that the effectiveness of this operation will wane over time. Artifical anal sphincter devices are no longer routinely offered. Sacral neuromodulation is the most effective treatment available for those who do not improve with conservative measures and remains effective in the long term. However, its exact mechanism of action remains elusive. New anal injectable devices and regenerative medicine therapies may offer some promise. For those who fail all other therapies, a stoma may be the last resort of use.

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References

  1. Parks AG, McPartlin JF. Late repair of injuries of the anal sphincter. Proc R Soc Med. 1971;64(12):1187–9.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Djusad S, Kouwagam AD. Repair of old total perineal rupture: a case series. J Surg Case Rep. 2023;2023(1):rjac628.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Zutshi M, Ferreira P, Hull T, Gurland B. Biological implants in sphincter augmentation offer a good short-term outcome after a sphincter repair. Color Dis. 2012;14(7):866–71.

    Article  CAS  Google Scholar 

  4. Engel AF, Kamm MA, Sultan AH, Bartram CI, Nicholls RJ. Anterior anal sphincter repair in patients with obstetric trauma. Br J Surg. 1994;81(8):1231–4.

    Article  CAS  PubMed  Google Scholar 

  5. Malouf AJ, Norton CS, Engel AF, Nicholls RJ, Kamm MA. Long-term results of overlapping anterior anal-sphincter repair for obstetric trauma. Lancet. 2000;355(9200):260–5.

    Article  CAS  PubMed  Google Scholar 

  6. Halverson AL, Hull TL. Long-term outcome of overlapping anal sphincter repair. Dis Colon Rectum. 2002;45(3):345–8.

    Article  PubMed  Google Scholar 

  7. Glasgow SC, Lowry AC. Long-term outcomes of anal sphincter repair for fecal incontinence: a systematic review. Dis Colon Rectum. 2012;55(4):482–90.

    Article  PubMed  Google Scholar 

  8. Cerdan, Santacruz C, Cerdan Santacruz DM, Milla Collado L, Ruiz de Leon A, Cerdan Miguel J. Multimodal Management of Fecal Incontinence Focused on Sphincteroplasty: long-term outcomes from a single center case series. J Clin Med. 2022;11(13):3755.

    Google Scholar 

  9. Ong K, Bordeianou L, Brunner M, Buntzen S, Collie MHS, Hanly A, et al. Changing paradigm of sacral neuromodulation and external anal sphincter repair for faecal incontinence in specialist centres. Color Dis. 2021;23(3):710–5.

    Article  CAS  Google Scholar 

  10. Lehur PA, Christoforidis D. Commentary on ‘Changing paradigm of sacral neuromodulation and external anal sphincter repair for faecal incontinence in specialist centres’. Color Dis. 2021;23(3):716–7.

    Article  Google Scholar 

  11. Matzel KE, Stadelmaier U, Hohenfellner M, Gall FP. Electrical stimulation of sacral spinal nerves for treatment of faecal incontinence. Lancet. 1995;346(8983):1124–7.

    Article  CAS  PubMed  Google Scholar 

  12. Carrington EV, Knowles CH. The influence of sacral nerve stimulation on anorectal dysfunction. Color Dis. 2011;13(Suppl 2):5–9.

    Article  Google Scholar 

  13. Knowles CH, de Wachter S, Engelberg S, Lehur P, Matzel KE, Zirpel L, et al. The science behind programming algorithms for sacral neuromodulation. Color Dis. 2021;23(3):592–602.

    Article  Google Scholar 

  14. Leroi AM, Parc Y, Lehur PA, Mion F, Barth X, Rullier E, et al. Efficacy of sacral nerve stimulation for fecal incontinence: results of a multicenter double-blind crossover study. Ann Surg. 2005;242(5):662–9.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Altomare DF, Giuratrabocchetta S, Knowles CH, Munoz Duyos A, Robert-Yap J, Matzel KE, et al. Long-term outcomes of sacral nerve stimulation for faecal incontinence. Br J Surg. 2015;102(4):407–15.

    Article  CAS  PubMed  Google Scholar 

  16. Boyle DJ, Murphy J, Gooneratne ML, Grimmer K, Allison ME, Chan CL, et al. Efficacy of sacral nerve stimulation for the treatment of fecal incontinence. Dis Colon Rectum. 2011;54(10):1271–8.

    Article  PubMed  Google Scholar 

  17. Maeda Y, Lundby L, Buntzen S, Laurberg S. Outcome of sacral nerve stimulation for fecal incontinence at 5 years. Ann Surg. 2014;259(6):1126–31.

    Article  PubMed  Google Scholar 

  18. Desprez C, Damon H, Meurette G, Mege D, Faucheron JL, Brochard C, et al. Ten-year evaluation of a large retrospective cohort treated by sacral nerve modulation for fecal incontinence: results of a French multicenter study. Ann Surg. 2022;275(4):735–42.

    Article  PubMed  Google Scholar 

  19. Leo CA, Thomas GP, Bradshaw E, Karki S, Hodgkinson JD, Murphy J, et al. Long-term outcome of sacral nerve stimulation for faecal incontinence. Color Dis. 2020;22(12):2191–8.

    Article  CAS  Google Scholar 

  20. Tan E, Ngo NT, Darzi A, Shenouda M, Tekkis PP. Meta-analysis: sacral nerve stimulation versus conservative therapy in the treatment of faecal incontinence. Int J Color Dis. 2011;26(3):275–94.

    Article  Google Scholar 

  21. Maeda Y, Lundby L, Buntzen S, Laurberg S. Suboptimal outcome following sacral nerve stimulation for faecal incontinence. Br J Surg. 2011;98(1):140–7.

    Article  CAS  PubMed  Google Scholar 

  22. Ratto C, Litta F, Parello A, Donisi L, De Simone V, Zaccone G. Sacral nerve stimulation in faecal incontinence associated with an anal sphincter lesion: a systematic review. Color Dis. 2012;14(6):e297–304.

    Article  CAS  Google Scholar 

  23. Huang Y, Koh CE. Sacral nerve stimulation for bowel dysfunction following low anterior resection: a systematic review and meta-analysis. Color Dis. 2019;21(11):1240–8.

    Article  CAS  Google Scholar 

  24. De Wachter S, Knowles CH, Elterman DS, Kennelly MJ, Lehur PA, Matzel KE, et al. New technologies and applications in sacral Neuromodulation: an update. Adv Ther. 2020;37(2):637–43.

    Article  PubMed  Google Scholar 

  25. Shafik A. Polytetrafluoroethylene injection for the treatment of partial fecal incontinence. Int Surg. 1993;78(2):159–61.

    CAS  PubMed  Google Scholar 

  26. Maeda Y, Laurberg S, Norton C. Perianal injectable bulking agents as treatment for faecal incontinence in adults. Cochrane Database Syst Rev. 2013;(2):CD007959.

    Google Scholar 

  27. Leo CA, Leeuwenburgh M, Orlando A, Corr A, Scott SM, Murphy J, et al. Initial experience with SphinKeeper intersphincteric implants for faecal incontinence in the UK: a two-Centre retrospective clinical audit. Color Dis. 2020;22(12):2161–9.

    Article  CAS  Google Scholar 

  28. Setti Carraro P, Kamm MA, Nicholls RJ. Long-term results of postanal repair for neurogenic faecal incontinence. Br J Surg. 1994;81(1):140–4.

    Article  CAS  PubMed  Google Scholar 

  29. Baeten C, Spaans F, Fluks A. An implanted neuromuscular stimulator for fecal continence following previously implanted gracilis muscle. Report of a case. Dis Colon Rectum. 1988;31(2):134–7.

    Article  CAS  PubMed  Google Scholar 

  30. Wong MT, Meurette G, Wyart V, Glemain P, Lehur PA. The artificial bowel sphincter: a single institution experience over a decade. Ann Surg. 2011;254(6):951–6.

    Article  PubMed  Google Scholar 

  31. Sugrue J, Lehur PA, Madoff RD, McNevin S, Buntzen S, Laurberg S, et al. Long-term experience of magnetic anal sphincter augmentation in patients with fecal incontinence. Dis Colon Rectum. 2017;60(1):87–95.

    Article  PubMed  Google Scholar 

  32. Mellgren A, Zutshi M, Lucente VR, Culligan P, Fenner DE, Group TS. A posterior anal sling for fecal incontinence: results of a 152-patient prospective multicenter study. Am J Obstet Gynecol. 2016;214(3):349 e1–8.

    Article  PubMed  Google Scholar 

  33. Frudinger A, Kolle D, Schwaiger W, Pfeifer J, Paede J, Halligan S. Muscle-derived cell injection to treat anal incontinence due to obstetric trauma: pilot study with 1 year follow-up. Gut. 2010;59(1):55–61.

    Article  CAS  PubMed  Google Scholar 

  34. Frudinger A, Pfeifer J, Paede J, Kolovetsiou-Kreiner V, Marksteiner R, Halligan S. Autologous skeletal-muscle-derived cell injection for anal incontinence due to obstetric trauma: a 5-year follow-up of an initial study of 10 patients. Color Dis. 2015;17(9):794–801.

    Article  CAS  Google Scholar 

  35. Sun L, Kuang M, Penn M, Damaser MS, Zutshi M. Stromal cell-derived factor 1 plasmid regenerates both smooth and skeletal muscle after anal sphincter injury in the long term. Dis Colon Rectum. 2017;60(12):1320–8.

    Article  PubMed  Google Scholar 

  36. Malone PS, Ransley PG, Kiely EM. Preliminary report: the antegrade continence enema. Lancet. 1990;336(8725):1217–8.

    Article  CAS  PubMed  Google Scholar 

  37. Thomas K, Bassuini M. Laparoscopic caecodivision ACE (antegrade continence enema) procedure. Tech Coloproctol. 2008;12(1):65–7.

    Article  CAS  PubMed  Google Scholar 

  38. Norton C, Burch J, Kamm MA. Patients’ views of a colostomy for fecal incontinence. Dis Colon Rectum. 2005;48(5):1062–9.

    Article  PubMed  Google Scholar 

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Correspondence to Gregory Thomas .

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Appendix: MCQ

Appendix: MCQ

Mark each item TRUE or FALSE

20.1.1 Questions

  1. 1.

    Anal incontinence is

    1. (A)

      More common in men

    2. (B)

      Linked to significant obstetric trauma

    3. (C)

      Always best managed with surgery

    4. (D)

      Often associated with other pelvic floor disorders

    5. (E)

      Likely to have a significant impact on quality of life of those affected

  2. 2.

    Regarding assessment and management of anl incontinence:

    1. (A)

      A rectal prolapse found at presentation may be left for conservative treatment

    2. (B)

      Lower GI endoscopy is indicated if rectal bleeding and/or a recent change in bowel habit is reported

    3. (C)

      Chronic loose stool should be investigated and corrected in the early stages of treatment

    4. (D)

      Endoanal ultrasonography may help determine what treatment may be offered

    5. (E)

      Biofeedback/ pelvic floor nursing therapy is unhelpful in most cases

  3. 3.

    Secondary anal sphincter repair:

    1. (A)

      May be offered for any type of sphincter defect

    2. (B)

      Maintains good outcomes in the long term for the majority

    3. (C)

      Requires prior endoanal ultrasonography and assessment of sphincter function

    4. (D)

      A covering colostomy should be used for all cases

    5. (E)

      May be combined with a soft tissue flap in the presence of significant perineal tissue loss

  4. 4.

    Sacral neuromodulation

    1. (A)

      Has a clearly defined mechanism of action

    2. (B)

      May be performed under local anaesthesia

    3. (C)

      Can be offered to those with a sphincter defect

    4. (D)

      Typically has a test stage

    5. (E)

      Once the device has been implanted, the patient may be discharged without the need for follow up

  5. 5.

    Regarding other surgical options for anal incontinence

    1. (A)

      There are a wide range of artificial anal sphincter devices currently available

    2. (B)

      Antegrade colonic enemas (ACE) are well tolerated in adults, with few complications

    3. (C)

      The “Sphinkeeper” anal injectable requires endoanal ultrasonography to achieve optimal device placement

    4. (D)

      A diverting colostomy should always be considered a “last resort” for those with severe faecal incontinence

    5. (E)

      Mucus leakage may persist after a colostomy

20.1.2 Answers

  1. 1.

    Anal incontinence is

    1. (A)

      FALSE

    2. (B)

      TRUE

    3. (C)

      FALSE

    4. (D)

      TRUE

    5. (E)

      TRUE

  2. 2.

    Regarding assessment and management of anl incontinence:

    1. (A)

      FALSE

    2. (B)

      TRUE

    3. (C)

      TRUE

    4. (D)

      TRUE

    5. (E)

      FALSE

  3. 3.

    Secondary anal sphincter repair:

    1. (A)

      FALSE

    2. (B)

      FALSE

    3. (C)

      TRUE

    4. (D)

      FALSE

    5. (E)

      TRUE

  4. 4.

    Sacral neuromodulation

    1. (A)

      FALSE

    2. (B)

      TRUE

    3. (C)

      TRUE

    4. (D)

      TRUE

    5. (E)

      FALSE

  5. 5.

    Regarding other surgical options for anal incontinence

    1. (A)

      FALSE

    2. (B)

      FALSE

    3. (C)

      TRUE

    4. (D)

      FALSE

    5. (E)

      TRUE

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Thomas, G., Vaizey, C. (2024). Surgical Management of Anal Incontinence. In: Sultan, A.H., Thakar, R., Lewicky-Gaupp, C. (eds) Pelvic Floor, Perineal, and Anal Sphincter Trauma During Childbirth. Springer, Cham. https://doi.org/10.1007/978-3-031-43095-4_20

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  • DOI: https://doi.org/10.1007/978-3-031-43095-4_20

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