Abstract
Hearing loss (HL) is a common cause of speech, language, and cognition delays. Hearing loss occurs in 1–3 newborns per 1000 births, with clinically significant or permanent HL in 1–2 per 1000 newborns and 2 per 1000 children [1, 2]. Early diagnosis of HL is critical, as improvement in speech and cognitive functions can be achieved with early intervention [3]. Pediatric HL can be categorized as congenital (genetic and non-genetic), acquired or sensorineural, conductive, and mixed [4]. Viral central nervous system (CNS) infections can lead to congenital and acquired HL, mainly sensorineural. This chapter will focus on acquired HL associated with viral meningitis and vaccines against viruses in children.
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References
Mehl AL, Thomson V. The Colorado newborn hearing screening project, 1992-1999: on threshold of effective population-based universal newborn hearing screening. Pediatrics. 2002;109:e7.
Fortnum HM, Summerfield AQ, Marshall DH, Davis AC, Bamford JM. Prevalence of permanent childhood hearing impairment in the United Kingdom and implications for universal neonatal hearing screening: questionnaire based ascertainment study. BMJ. 2001;323:536–40.
Ching TYC, Dillon H, Button L, et al. Age at intervention for permanent hearing loss and 5-year language outcomes. Pediatrics. 2017;140:e20164274.
Erenberg A, Lemons J, Sia C, Trunkel D, Ziring P. Newborn and infant hearing loss: detection and intervention. Academy of Pediatrics Task Force on Newborn and Infant Hearing, 1998-1999. Pediatrics. 1999;103:527–30.
Logan SA, MacMahon E. Viral meningitis. BMJ. 2008;336:36–40.
Shukla B, Aguilera AE, Salazar L, Wootton SH, Kaewpoowat Q, Hasbun R. Aseptic meningitis in adults and children: diagnostic and management challenges. J Clin Virol. 2017;94:110–4.
Kohil A, Jemmieh S, Smatti MK, Yassine HM. Viral meningitis: an overview. Arch Virol. 2021;166:335–45.
Abid FB, Abukhattab A, Ghazouani H, et al. Epidemiology and clinical outcomes of viral central nervous system infections. Int J Infect Dis. 2018;73:85–90.
Romero JR. Coxsackieviruses, echoviruses, and numbered enteroviruses (EV-A71, EVD-68, EVD-70). In: Bennett JE, Dolin R, Blaser MJ, editors. Mandell, Douglas and Bennett’s principles and practice of infectious diseases. 9th ed. Philadelphia: Elsevier; 2020. p. 2227–37.
Michos AG, Syriopoulou VP, Daikos GL, et al. Aseptic meningitis in children: analysis of 506 cases. PLoS One. 2007;2:e674.
Hviid A, Melbye M. The epidemiology of viral meningitis hospitalization in childhood. Epidemiology. 2007;18:695–701.
Dumaidi K, Al-Jawabreh A. Molecular detection and genotyping of enteroviruses from CSF samples of patients with suspected sepsis-like illness and/or aseptic meningitis from 2012 to 2015 in West Bank, Palestine. PLoS One. 2017;12:e0172357.
Kadambari S, Braccio S, Ribeiro S, et al. Enterovirus and parechovirus meningitis in infants younger than 90 days old in the UK and Republic of Ireland: a British Paediatric Surveillance Unit study. Arch Dis Child. 2019;104:552–7.
Haydar SM, Hallit SR, Hallit RR, et al. Adherence to international guidelines for the treatment of meningitis infections in Lebanon. Saudi Med J. 2019;40:260–5.
Koyuncu OO, Hogue IB, Enquist LW. Virus infections in the nervous system. Cell Host Microbe. 2013;13:379–93.
Onarecker TR, Romero JR. Aseptic and viral meningitis. In: Long SS, Prober CG, Fischer M, Kimberlin DW, editors. Principles and practice of pediatric infectious diseases. 6th ed. Philadelphia: Elsevier; 2023. p. 310–5.
Pinninti SG, Kimberlin DW. Neonatal herpes simplex virus infections. Semin Perinatol. 2018;42:168–75.
Hou J, Baker LA, Zhou L, Klein RS. Viral interactions with the blood-brain barrier: old dog, new tricks. Tissue Barriers. 2016;4:e1142492.
Cassady KA, Whitley RJ. Pathogenesis and pathophysiology of viral central nervous system infections. In: Scheld WM, Whitley R, Marra MC, editors. Infections of the central nervous system. 3rd ed. Philadelphia: Lippincott-Raven; 2004. p. 57–74.
Bronstein DE, Glaser CA. Aseptic meningitis and viral meningitis. In: Cherry JD, Harrison GJ, Kaplan SL, Steinbach WJ, Hotez PJ, editors. Feigin and Cherry’s textbook of pediatric infectious diseases. 8th ed. Philadelphia: Elsevier; 2019. p. 355–61.
Visintin C, Mugglestone MA, Fields EJ, Jacklin P, Murphy MS, Pollard AJ. Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance. BMJ. 2010;340:c3209.
Mehndiratta M, Rayak N, Garg H, Kumar M, Pandey S. Appraisal of Kernig’s and Brudzinski’s sign in meningitis. Ann Indian Acad Neurol. 2012;15:287–8.
Waghdhare S, Kalantri A, Joshi R, Kalantri S. Accuracy of physical signs for detecting meningitis: a hospital-based diagnostic accuracy study. Clin Neurol Neurosurg. 2010;112:752–7.
Iguchi M, Noguchi Y, Yamamoto S, Tanaka Y, Tsujimoto H. Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting. Cochrane Database Syst Rev. 2020;6:CD012824.
Romero JR, Newland JG. Viral meningitis and encephalitis: traditional and emerging viral agents. Semin Pediatr Infect Dis. 2003;14:72–82.
Pérez Méndez C, Oña Navarro M, Ballesteros García S, et al. Enteroviral meningitis. Clinical and laboratory findings in a series of 60 children. An Esp Pediatr. 2001;55:11–4.
Parikh V, Tucci V, Galwankar S. Infections of the nervous system. Int J Crit Illn Inj Sci. 2012;2:82–97.
Irani DN. Aseptic meningitis and viral myelitis. Neurol Clin. 2008;26:635–55.
Chang LY, Huang LM, Gau SS, et al. Neurodevelopment and cognition in children after enterovirus 71 infection. N Engl J Med. 2007;356:1226–34.
Wu JM, Wang JN, Tsai YC, et al. Cardiopulmonary manifestations of fulminant enterovirus 71 infection. Pediatrics. 2002;109:e26.
Pastula DM, Aliabadi N, Haynes AK, et al. Acute neurologic illness of unknown etiology in children—Colorado, August–September 2014. MMWR Morb Mortal Wkly Rep. 2014;63:901–2.
Britton PN, Dale RC, Nissen MD, et al. Parechovirus encephalitis and neurodevelopmental outcomes. Pediatrics. 2016;137:e20152848.
Rudolph H, Schroten H, Tenenbaum T. Enterovirus infections of the central nervous system in children an update. Pediatr Infect Dis J. 2016;35:567–9.
Bearden D, Collett M, Quan PL, Costa-Carvalho BT, Sullivan KE. Enteroviruses in X-linked agammaglobulinemia: update on epidemiology and therapy. J Allergy Clin Immunol Pract. 2016;4:1059–65.
Damsgaard J, Hjerrild S, Andersen H, Leutscher PDC. Long-term neuropsychiatric consequences of aseptic meningitis in adult patients. Infect Dis. 2015;47:357–63.
Schmidt H, Cohrs S, Heineman T, et al. Sleep disorders are long-term sequelae of both bacterial and viral meningitis. J Neurol Neurosurg Psychiatry. 2006;77:554–8.
Hudson JA, Broad J, Martin NG, et al. Outcomes beyond hospital discharge in infants and children with viral meningitis: a systematic review. Rev Med Virol. 2020;300:e2083.
Chang LY, Lin HY, Gau SSF, et al. Enterovirus A71 neurologic complications and long-term sequelae. J Biomed Sci. 2019;26:57.
Buch K, Bodilsen J, Knudsen A, et al. Cerebrospinal fluid lactate as a marker to differentiate between community-acquired acute bacterial meningitis and aseptic meningitis/encephalitis in adults: a Danish prospective observational cohort study. Infect Dis (Lond). 2018;50:514–21.
de Crom SC, van Furth MA, Peeters MF, Rossen JW, Obihara CC. Characteristics of pediatric patients with enterovirus meningitis and no cerebral fluid pleocytosis. Eur J Pediatr. 2012;171:795–800.
Alhazmi A, Lazrek M, Alidjinou EK, Descombes G, Engelmann I, Hober D. Paediatric enterovirus meningitis without cerebrospinal fluid pleocytosis. J Infect. 2019;79:612–25.
Jaijakul S, Salazar L, Wootton SH, Aguilera E, Hasbun R. The clinical significance of neutrophilic pleocytosis in cerebrospinal fluid in patients with viral central nervous system infections. Int J Infect Dis. 2017;59:77–81.
Ohst C, Saschenbrecker S, Stiba K, et al. Reliable serological testing for the diagnosis of emerging ınfectious diseases. In: Hilgenfeld R, Vasudevan SG, editors. Dengue and Zika: control and antiviral treatment strategies, Advances in experimental medicine and biology, vol. 1062. Singapore: Springer; 2018. p. 19–43.
Verstrepen WA, Kuhn S, Kockx MM, Van De Vyvere ME, Mertens AH. Rapid detection of enterovirus RNA in cerebrospinal fluid specimens with a novel single-tube real-time reverse transcription-PCR assay. J Clin Microbiol. 2001;39:4093–6.
Khumalo J, Nicol M, Hardie D, Muloiwa R, Mteshana P, Bamford C. Diagnostic accuracy of two multiplex real-time polymerase chain reaction assays for the diagnosis of meningitis in children in a resource-limited setting. PLoS One. 2017;12:e0173948.
Mintegi S, García S, Martín MJ, et al. Clinical prediction rule for distinguishing bacterial from aseptic meningitis. Pediatrics. 2020;146:e20201126.
Gaieski DF, O’Brien NF, Hernandez R. Emergency neurologic life support: meningitis and encephalitis. Neurocrit Care. 2017;27(Suppl 1):124–33.
Wall EC, Chan JM, Gil E, Heyderman RS. Acute bacterial meningitis. Curr Opin Neurol. 2021;34:386–95.
Momméja-Marin H, Lafaurie M, Scieux C, Galicier L, Oksenhendler E, Molina JM. Herpes simplex virus type 2 as a cause of severe meningitis in immunocompromised adults. Clin Infect Dis. 2003;37:1527–33.
Kaewpoowat Q, Salazar L, Aguilera E, Wootton SH, Hasbun R. Herpes simplex and varicella zoster CNS infections: clinical presentations, treatments and outcomes. Infection. 2016;44:337–45.
Hassan STS, Šudomová M, Berchová-Bímová K, Šmejkal K, Echeverría J. Psoromic acid, a lichen-derived molecule, ınhibits the replication of HSV-1 and HSV-2, and inactivates HSV-1 DNA polymerase: shedding light on antiherpetic properties. Molecules. 2019;24:2912.
Desmond RA, Accortt NA, Talley L, et al. Enteroviral meningitis: natural history and outcome of pleconaril therapy. Antimicrob Agents Chemother. 2006;50:2409–14.
Rorabaugh ML, Berlin LE, Heldrich F, et al. Aseptic meningitis in infants younger than 2 years of age: acute illness and neurologic complications. Pediatrics. 1993;92:206–11.
Rotbart HA. Viral meningitis. Semin Neurol. 2000;20:277–92.
Kaplan MH, Klein SW, McPhee J, Harper RG. Group B coxsackievirus infections in infants younger than three months of age: a serious childhood illness. Rev Infect Dis. 1983;5:1019–32.
Modlin JF. Perinatal echovirus infection: insights from a literature review of 61 cases of serious infection and 16 outbreaks in nurseries. Rev Infect Dis. 1986;8:918–26.
Management of genital herpes in pregnancy. ACOG practice bulletin summary, number 220. Obstet Gynecol. 2020;135:1236–8.
Li ML, Shih SR, Tolbert B, Brewer G. Enterovirus A71 vaccines. Vaccines (Basel). 2021;9:199.
Cohen BE, Durstenfeld A, Roehm PC. Viral causes of hearing loss: a review for hearing health professionals. Trends Hear. 2014;18:2331216514541361.
Greco A, Fusconi M, Gallo A, Marinelli C, Macri GF, Vincentiis MD. Sudden sensorineural hearing loss: an autoimmune disease? Autoimmun Rev. 2011;10:756–61.
Smith RJH, Bale JF, White KR. Sensorineural hearing loss in children. Lancet. 2005;365:879–90.
Nikolopoulos TP, Dyar D, Gibbin KP. Assessing candidate children for cochlear implantation with the Nottingham Children’s Implant Profile (NChIP): the first 200 children. Int J Pediatr Otorhinolaryngol. 2004;68:127–35.
Graham ME, Dedhia K, Park AH. Early detection and diagnosis of infant hearing impairment. In: Flint P, Haughey B, Lund V, et al., editors. Cummings otolaryngology head and neck surgery. 7th ed. Philadelphia: Elsevier; 2021. p. 2887–97.
Kim H, Kim MW, Nam DH, Kang EY, Yang HS. Efficacy of auditory evoked potential follow-up in viral meningitis of infants. Childs Nerv Syst. 2020;3077-3083:3077.
Jiang F, Kuper H, Bright T, Qin WZ. Etiology of childhood bilateral sensorineural hearing loss in Shandong province, China. Am J Audiol. 2020;36:236–43.
Gupta RK, Best J, MacMahon E. Mumps and the UK epidemic 2005. BMJ. 2005;330:1132–5.
Sanayake SN. Mumps: a resurgent disease with protean manifestations. Med J Aust. 2008;189:456–9.
Bjorvatn B, Wolontis S. Mumps meningoencephalitis in Stockholm, November 1964-July 1971. I. Analysis of a hospitalized study group. Questions of selection and representativity. Scand J Infect Dis. 1973;5:253–60.
Johnstone JA, Ross CA, Dunn M. Meningitis and encephalitis associated with mumps infection. A 10-year survey. Arch Dis Child. 1972;47:647–51.
Koskiniemi M, Donner M, Pettay O. Clinical appearance and outcome in mumps encephalitis in children. Acta Paediatr Scand. 1983;72:603–9.
Murray HG, Field CM, McLeod WJ. Mumps meningoencephalitis. Br Med J. 1960;1:1850–3.
Hashimoto H, Fujioka M, Kinumaki H. An office-based prospective study of deafness in mumps. Pediatr Infect Dis J. 2009;28:173–5.
Vuori M, Lahikainen EA, Peltonen T. Perceptive deafness in connection with mumps. A study of 298 servicemen suffering from mumps. Acta Otolaryngol. 1962;55:231–6.
Everberg G. Deafness following mumps. Acta Otolaryngol. 1957;48:397–403.
Takagi A, Ohfuji S, Nakano T, Kumihashi H, Kano M, Tanaka T. Incidence of mumps deafness in Japan, 2005-2017: analysis of Japanese ınsurance claims database. J Epidemiol. 2022;32:21–6.
Hviid A, Rubin S, Muhlemann K. Mumps. Lancet. 2008;371:932–44.
Kawashima Y, Ihara K, Nakamura M, Nakashima T, Fukuda S, Kitamura K. Epidemiological study of mumps deafness in Japan. Auris Nasus Larynx. 2005;32:125–8.
Yanagita N, Murahashi K. A comparative study of mumps deafness and idiopathic profound sudden deafness. Arch Otorhinolaryngol. 1986;243:197–9.
Morita S, Fujiwara K, Fukuda A, et al. The clinical features and prognosis of mumps-associated hearing loss: a retrospective, multi-institutional investigation in Japan. Acta Otolaryngol. 2017;137(sup565):s44–7.
Nomura Y. Diagnostic criteria for sudden deafness, mumps deafness and perilymphatic fistula. Acta Otolaryngol Suppl. 1988;456:7–8.
Nomura Y, Harada T, Sakata H, Sugiura A. Sudden deafness and asymptomatic mumps. Acta Otolaryngol Suppl. 1988;456:9–11.
Okamoto M, Shitara T, Nakayama M, et al. Sudden deafness accompanied by asymptomatic mumps. Acta Otolaryngol Suppl. 1994;514:45–8.
Fukuda S, Chida E, Kuroda T, Kashiwamura M, Inuyama Y. An anti-mumps IgM antibody level in the serum of idiopathic sudden sensorineural hearing loss. Auris Nasus Larynx. 2001;28(Suppl):s3–5.
Fukuda A, Morita S, Nakamaru Y, et al. Anti-mumps IgM antibody positive rate with sudden sensorineural hearing loss using second-generation enzyme immunoassay: a retrospective, multi-institutional investigation in Hokkaido, Japan. Auris Nasus Larynx. 2018;45:911–5.
Galazka AM, Robertson SE, Kraighter A. Mumps and mumps vaccine: a global review. Bull World Health Organ. 1999;77:3–14.
Lindsay JR. Histopathology of deafness due to postnatal viral disease. Arch Otolaryngol. 1973;98:258–64.
Westmore GA, Pickard BH, Stern H. Isolation of mumps virus from the inner ear after sudden deafness. Br Med J. 1979;1:14–5.
Katsushika M, Kashio A, Ogata E, et al. Outcomes of cochlear implantations for mumps deafness: a report of four pediatric cases. Int J Pediatr Otorhinolaryngol. 2018;114:76–9.
Noda T, Kakazu Y, Komune S. Cochlear implants for mumps deafness: two paediatric cases. J Laryngol Otol. 2015;129(Suppl 2):s38–41.
McKenna MJ. Measles, mumps, and sensorineural hearing loss. Ann N Y Acad Sci. 1997;830:291–8.
Suboti R. Histopathological findings in the inner ear caused by measles. J Laryngol Otol. 1976;90:173–81.
Fukuda S, Ishikawa K, Inuyama Y. Acute measles infection in the hamster cochlea. Acta Otolaryngol Suppl. 1994;514:111–6.
Sagar PR, Shah P, Bollampally VC, Alhumaidi N, Malik BH. Otosclerosis and measles: do measles have a role in otosclerosis? A review article. Cureus. 2020;12:e9908.
Noda M, Maeda Y, Kataoka Y, Nishizaki K. Paediatric varicella zoster virus infection causing sudden hearing loss. B-ENT. 2018;14:147–51.
Shao M, Xiong G, Xiang G, Xu S, Zheng Y, Zhang L. Sudden deafness as an initial presentation of varicella: case report and literature review. Ann Palliat Med. 2021;10:5891–6.
Schwab J, Ryan M. Varicella zoster virus meningitis in a previously immunized child. Pediatrics. 2004;114:e273–4.
Veltri RW, Wilson WR, Sprinkle PM, Rodman SM, Kavesh DA. The implication of viruses in idiopathic sudden hearing loss: primary infection or reactivation of latent viruses? Otolaryngol Head Neck Surg. 1981;89:137–41.
Alsanosi AA, Influenza A. (H1N1): a rare cause of deafness in two children. J Laryngol Otol. 2012;126:1274–5.
Zhang N, Zuo Y, Jiang L, Peng Y, Huang X, Zuo L. Epstein-Barr virus and neurological diseases. Front Mol Biosci. 2022;8:816098.
Wang Y, Yang J, Wen Y. Lessons from Epstein-Barr virus DNA detection in cerebrospinal fluid as a diagnostic tool for EBV-induced central nervous system dysfunction among HIV-positive patients. Biomed Pharmacother. 2022;145:112392.
Kelly MJ, Benjamin LA, Cartwright K, et al. Epstein-Barr virus coinfection in cerebrospinal fluid is associated with increased mortality in Malawian adults with bacterial meningitis. J Infect Dis. 2012;205:106–10.
Kleines M, Schiefer J, Stienen A, Blaum M, Ritter K, Häusler M. Expanding the spectrum of neurological disease associated with Epstein-Barr virus activity. Eur J Clin Microbiol Infect Dis. 2011;30:1561–9.
Miyashita T, Kobayashi Z, Numasawa Y, Akaza M, Ishihara S, Shintani S. Epstein-Barr virus-associated meningitis presenting with hearing impairment. Intern Med. 2012;51:1755–7.
Yossepowitch O, Lossos A, Lossos IS. Sudden hearing loss following acute hepatitis. Postgrad Med J. 1999;75:309–12.
Arslan F, Karagöz E, Beköz HS, Ceylan B, Mert A. Epstein-Barr virus-associated haemophagocytic lymphohistiocytosis presenting with acute sensorineural hearing loss: a case report and review of the literature. Infez Med. 2017;3:277–80.
McBride W, Gill KR, Wiviott L. West Nile virus infection with hearing loss. J Infect. 2006;53:e203–5.
Jamison SC, Michaels SR, Ratard R, Sweet JM, Deboisblanc BP. A 41-year-old HIV-positive man with acute onset of quadriplegia after West Nile virus infection. South Med J. 2007;100:1051–3.
Casetta I, Ciorba A, Cesnik E, Trevisi P, Tugnoli V, Bovo R. West Nile virus neuroinvasive disease presenting with acute flaccid paralysis and bilateral sensorineural hearing loss. J Neurol. 2011;258:1880–1.
Weatherhead JE, Miller VE, Garcia MN, et al. Long-term neurological outcomes in West Nile virus-infected patients: an observational study. Am J Trop Med Hyg. 2015;92:1006–12.
Khalil A, Moutranb H, Corr C, Elias F. A case of West Nile viral encephalitis with reversible hearing loss in an immunocompetent patient. Abstracts/Int J Infect Dis. 2016;53S:4–163.
Parrino D, Brescia G, Trimarchi MV, et al. Cochlear-vestibular impairment due to West Nile virus infection. Ann Otol Rhinol Laryngol. 2019;128:1198–202.
Ficenec SC, Percak J, Arguello S, et al. Lassa fever induced hearing loss: the neglected disability of hemorrhagic fever. Int J Infect Dis. 2020;100:82–7.
Ibekwe TS, Okokhere PO, Asogun D, et al. Early-onset sensorineural hearing loss in Lassa fever. Eur Arch Otorhinolaryngol. 2011;268:197–201.
Yun NE, Ronca S, Tamura A, et al. Animal model of sensorineural hearing loss associated with Lassa virus infection. J Virol. 2015;90:2920–7.
Okokhere P, Colubri A, Azubike C, et al. Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study. Lancet Infect Dis. 2018;18:684–95.
Okokhere PO, Ibekwe TS, Akpede GO. Sensorineural hearing loss in Lassa fever: two case reports. J Med Case Rep. 2009;3:36.
Grahn A, Bråve A, Lagging M, et al. Imported case of Lassa fever in Sweden with encephalopathy and sensorineural hearing deficit. Open Forum Infect Dis. 2016;3:ofw198.
Mateer EJ, Huang C, Shehu NY, Paessler S. Lassa fever-induced sensorineural hearing loss: a neglected public health and social burden. PLoS Negl Trop Dis. 2018;12:e0006187.
Cashman KA, Wilkinson ER, Zeng X, et al. Immune-mediated systemic vasculitis as the proposed cause of sudden-onset sensorineural hearing loss following Lassa virus exposure in Cynomolgus macaques. MBio. 2018;9:e01896–18.
Edington G, White H. The pathology of Lassa fever: a tribute to the late Dr. J. M. Troup. Trans R Soc Trop Med Hyg. 1972;66:381–9.
Mentel R, Kaftan H, Wegner U, Reissmann A, Gürtler L. Are enterovirus infections a co-factor in sudden hearing loss? J Med Virol. 2004;72:625–9.
Schattner A, Halperin D, Wolf D, Zimhony O. Enteroviruses and sudden deafness. CMAJ. 2003;168:1421–3.
Anderson SM, Gold D, Olson G, Pisano J. Chronic aseptic meningitis caused by enterovirus in a humorally immunosuppressed adult patient presenting with sensorineural hearing loss: a case report. BMC Infect Dis. 2022;22:16.
Kenna MA. Acquired hearing loss in children. Otolaryngol Clin N Am. 2015;48:933–53.
Wilson WR. The relationship of the herpesvirus family to sudden hearing loss: a prospective clinical study and literature review. Laryngoscope. 1986;96:870–7.
Chand RP, Jan A, Vyas H. Acute sensorineural deafness following herpes simplex infection. Eur J Pediatr. 1993;152:379.
Al Muhaimeed H, Zakzouk SM. Hearing loss and herpes simplex. J Trop Pediatr. 1997;43:20–4.
Nomura Y, Kurata T, Saito K. Cochlear changes after herpes simplex virus infection. Acta Otolaryngol. 1985;99:419–27.
Studahl M, Lindquist L, Eriksson BM, et al. Acute viral infections of the central nervous system in immunocompetent adults: diagnosis and management. Drugs. 2013;73:131–58.
Bentivi JO, de Azevedo CMPES, Lopes MKD, et al. Audiological assessment of children with HIV/AIDS: a meta-analysis. J Pediatr. 2020;96:537–45.
Htapcak S, Kuper H, Bartlett P, et al. Hearing loss in HIV-infected children in Lilongwe, Malawi. PLoS One. 2016;11:e0161421.
Dawood G, Klop D, Olivier E, Elliott H, Pillay M, Grimmer K. Nature and extent of hearing loss in HIV-infected children: a scoping review. Int J Pediatr Otorhinolaryngol. 2020;134:110036.
Christopher N, Edward T, Sabrina BK, Agnes N. The prevalence of hearing impairment in the 6 months-5 years HIV/AIDS-positive patients attending paediatric infectious disease clinic at Mulago Hospital. Int J Pediatr Otorhinolaryngol. 2013;77:262–5.
Rarey KE. Otologic pathophysiology in patients with human immunodeficiency virus. Am J Otolaryngol. 1990;11:366–9.
Timon CI, Walsh MA. Sudden sensorineural hearing loss as a presentation of HIV infection. J Laryngol Otol. 1989;103:1071–2.
van der Westhuizen Y, Swanepoel de W, Heinze B, Hofmeyr LM. Auditory and otological manifestations in adults with HIV/AIDS. Int J Audiol. 2013;52:37–43.
Vincenti V, Pasanisi E, Bacciu A, et al. Cochlear implantation in a human immunodeficiency virus-infected patient. Laryngoscope. 2005;115:1079–81.
De Luca P, Scarpa A, Ralli M, et al. Auditory disturbances and SARS-CoV-2 ınfection: brain ınflammation or cochlear affection? Systematic review and discussion of potential pathogenesis. Front Neurol. 2021;12:707207.
Tufatulin GS, Boboshko MY, Garbaruk ES, et al. Hearing function in children after new coronavirus infection (COVID-19). Vestn Otorinolaringol. 2021;86:28–34 [article in Russian, abstract in English].
Saki N, Karimi M, Bayat A. Cochlear implant failure following COVID 19: report of two cases. Am J Otolaryngol. 2021;42:102910.
Ghiselli S, Laborai A, Biasucci G, Carvelli M, Salsi D, Cuda D. Auditory evaluation of infants born to COVID19 positive mothers. Am J Otolaryngol. 2022;43:103379.
Nabe-Nielsen J, Walter B. Unilateral total deafness as a complication of the measles-mumps-rubella vaccination. Scand Audiol Suppl. 1988;30:69–70.
Kaga K, Ichimura K, Ihara M. Unilateral total loss of auditory and vestibular function as a complication of mumps vaccination. Int J Pediatr Otorhinolaryngol. 1998;43:73–5.
Rikitake M, Sampei S, Komori M, Sakurai Y, Kojima H. Bilateral deafness as a complication of the vaccination-a case report. Int Tinnitus J. 2018;22:19–22.
Murray MW, Lewis MJ. Mumps meningitis after measles, mumps, and rubella vaccination. Lancet. 1989;2:677.
Belyaletdinova IK, Mitrofanova IV, Kozlovskaya LI, Ignatyev GM. Cases of aseptic meningitis after vaccination against mumps in Russia (2009-2019). Public Health. 2020;186:8–11.
Brodsky L, Stanievich J. Sensorineural hearing loss following live measles virus vaccination. Int J Pediatr Otorhinolaryngol. 1985;10:159–63.
Stewart BJ, Prabhu PU. Reports of sensorineural deafness after measles, mumps, and rubella immunisation. Arch Dis Child. 1993;69:153–4.
Jayajaran V, Sedler PA. Hearing loss following measles vaccination. J Infect. 1995;30:184–5.
Asatryan A, Pool V, Chen RT, Kohl KS, Davis RL, Iskander JK. Live attenuated measles and mumps viral strain containing vaccines and hearing loss: vaccine adverse event reporting system (VAERS), United States, 1990–2003. Vaccine. 2008;26:1166–72.
Huang HH, Huang CC, Hsueh PY, Lee TJ. Bilateral sudden deafness following H1N1 vaccination. Otolaryngol Head Neck Surg. 2010;143:849–50.
Kolarov C, Lobermann M, Fritzsche C, Hemmer C, Mlynski R, Reisinger EC. Bilateral deafness two days following influenza vaccination: a case report. Hum Vaccin Immunother. 2019;15:107–8.
Orlando MP, Masieri S, Pascarella MA, CiofaloA FF. Sudden hearing loss in childhood consequent to hepatitis B vaccination: a case report. Ann N Y Acad Sci. 1997;830:319–21.
Biacabe B, Erminy M, Bonfils P. A case report of fluctuant sensorineural hearing loss after hepatitis B vaccination. Auris Nasus Larynx. 1997;24:357–60.
Davanipour Z, Stewart CE, McGann DG. Hepatitis B vaccination and asymmetrical tinnitus and hearing loss. Clin Res. 1994;42:341A.
Hemachudha T, Phanuphak P, Johnson RT, Griffin DE, Ratanavongsiri J, Siriprasomsup W. Neurologic complications of Semple-type rabies vaccine: clinical and immunological studies. Neurology. 1987;37:550–6.
Manning SE, Rupprecht CE, Fishbein D, et al. Human rabies prevention-United States, 2008: recommendations of the Advisory Committee on Immunization Practices. MMWR Recomm Rep. 2008;57:1–28.
World Health Organization. WHO Expert Consultation on Rabies. Second report. World Health Organ Tech Rep Ser. 2013;982:1–139. http://apps.who.int/iris/bitstream/10665/85346/1/9789240690943_eng.pdf. Accessed 30 Dec 2022.
Sabchareon A, Lang J, Attanath P, et al. A new Vero cell rabies vaccine: results of a comparative trial with human diploid cell rabies vaccine in children. Clin Infect Dis. 1999;29:141–9.
Fishbein DB, Dreesen DW, Holmes DF, Teplis CF, Mehta N, Briggs DJ. Human diploid cell rabies vaccine purified by zonal centrifugation: a controlled study of antibody response and side effects following primary and booster pre-exposure immunizations. Vaccine. 1989;7:437–42.
Fishbein DB, Yenne KM, Dreesen DW, et al. Risk factors for systemic hypersensitivity reactions after booster vaccinations with human diploid cell rabies vaccine: a nationwide prospective study. Vaccine. 1993;11:1390–4.
Dreesen DW, Fishbein DB, Kemp DT, Brown J. Two-year comparative trial on the immunogenicity and adverse effects of purified chick embryo cell rabies vaccine for pre-exposure immunization. Vaccine. 1989;7:397–400.
Kulkarni PS, Sapru A, D’Costa PM, et al. Safety and immunogenicity of a new purified Vero cell rabies vaccine (PVRV) administered by intramuscular and intradermal routes in healthy volunteers. Vaccine. 2013;31:2719–22.
Mattner F, Bitz F, Goedecke M, et al. Adverse effects of rabies pre and postexposure prophylaxis in 290 health-care workers exposed to rabies infected organ donor or transplant recipients. Infection. 2007;35:219–24.
Güçlü O, Dereköy FS. Sudden hearing loss after rabies vaccination. Balkan Med J. 2013;30:327–8.
Okhovat S, Fox R, Magill J, Narula A. Sudden onset unilateral sensorineural hearing loss after rabies vaccination. BMJ Case Rep. 2015;2015:bcr2015211977.
Gupta D, Singh G, Tijender. A case report of sudden hearing loss after rabies vaccination. IP J Otorhinolaryngol Allied Sci. 2021;4:139–41.
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Kara, B., Güngör, M., Arısoy, E.S., Demmler-Harrison, G.J. (2023). Viral Meningitis in Children and Hearing Loss. In: Arısoy, A.E., Arısoy, E.S., Bayar Muluk, N., Cingi, C., Correa, A.G. (eds) Hearing Loss in Congenital, Neonatal and Childhood Infections. Comprehensive ENT. Springer, Cham. https://doi.org/10.1007/978-3-031-38495-0_24
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