Skip to main content

Abstract

Khus (Vetiver), a significant perennial aromatic grass that may grow up to 2 meters in height, is a member of the Poaceae family. The plant has a distinctive trait that allows it to thrive in a wide variety of soil pH conditions and tolerate extended periods of seasonal floods in addition to prolonged drought. It has been used as a blood cleanser, tonic, and cooling agent since ancient times and believed to have a relaxing impact on the nervous system and is used to treat various skin problems like ringworm, indigestion, and appetite loss. It is also grown for the essential oil that is extracted from its roots. Therefore, vetiver oil is a highly valued essential component for modern perfumery and has been regarded as a high-class perfume. Its cultivation is therefore certainly an enterprise driven by profit.As one of the ingredients, C. zizanioides is used in the preparation of many traditional ayurvedic medicines, including those listed below: Fighter Hand Sanitizer, Yograj Guggul, Ushira Powder, Shadanga Paneeya, Nilavembu Churna, Sri SriTattva Ushira Syrup, Ushirasava, Trichup Herbal Hair Pack Powder, Prosman, and Balar are some examples of herbal hair products.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Stevens, P. F. (2017). Angiosperm phylogeny website (Version 14). Missouri Botanical Garden St. Louis.

    Google Scholar 

  2. Clayton, W. D., Vorontsova, M. S., Harman, K. T., & Williamson, H. (2016). GrassBase-the online world grass flora. GrassBase-The Online World Grass Flora.

    Google Scholar 

  3. Presl, K. B. (1830). Reliquiae Haenkeanae, seu Descriptiones et icones plantarum, quas in America Meridionali et Boreali, in insulis Philippinis et Marianis collegit Thaddaeus Haenke (Vol. 1). apud JG Calve.

    Google Scholar 

  4. Veldkamp, J. F. (1999). A revision of Chrysopogon Trin. Including Vetiveria Bory (Poaceae) in Thailand and Malesia with notes on some other species from Africa and Australia. Austrobaileya, 5, 503–533.

    Article  Google Scholar 

  5. Kottekkattu, T., & Pradeep, A. K. (2014). Chrysopogon festucoides (Poaceae): A new record for South India. Rheedea, 24(1), 56–59.

    Google Scholar 

  6. Sunil, C. N., Narayanan, M. R., Sivadasan, M., Shaju, T., Kumar, V. N., & Alfarhan, A. H. (2017). A new species of Chrysopogon (Poaceae: Andropogoneae) from India. Phytotaxa, 307(4), 245–253.

    Article  Google Scholar 

  7. Linnaeus, C. (2017). Phalaris zizanioides. In Mantissa plantarum Altera (Vol. 947, p. 190). Laurentii Salvii/Holmiae.

    Google Scholar 

  8. De Guzmam, C. C., & Oyen, L. P. A. (1999). Vetiveria zizanioides (L) Nash. In Plant resources of South-East Asia 19 essential oil plants (pp. 167–172). Backhuys Publishers.

    Google Scholar 

  9. Adams, R. P., McDaniel, C. A., & Carter, F. L. (1988). Termiticidal activities in the heartwood, bark/sapwood and leaves of Juniperus species from the United States. Biochemical Systematics and Ecology, 16(5), 453–456.

    Article  Google Scholar 

  10. PIER. (2018). Pacific Island ecosystem at risk. IOP publishing Pacific Island ecosystem at risk Honolulu Hawaii. HEAR/University of Hawaii.

    Google Scholar 

  11. USDA-ARS. (2020). Germplasm Resources Information Network (GRIN). Online Database. National Germplasm Resources Laboratory.

    Google Scholar 

  12. Weber, E., Sun, S. G., & Li, B. (2008). Invasive alien plants in China: Diversity and ecological insights. Biological Invasions, 10(8), 1411–1429.

    Article  Google Scholar 

  13. Zhang, W., Liu, J. X., & Huo, P. H. (2017). Phoma herbarum causes leaf spots and blight on vetiver grass (Vetiveria zizanioides L.) in southern China. Plant Disease, 101(10), 1823.

    Article  Google Scholar 

  14. Jian, O. U., Changyi, L. U., & O'TOOLE, D. K. (2008). A risk assessment system for alien plant bio-invasion in Xiamen, China. Journal of Environmental Sciences, 20(8), 989–997.

    Article  Google Scholar 

  15. Chong, K. Y., Tan, H. T., & Corlett, R. T. (2009). A checklist of the total vascular plant flora of Singapore: Native, naturalised and cultivated species. National University of Singapore.

    Google Scholar 

  16. Zuloaga, F. O., Morrone, O., Davidse, G., Filgueiras, T. S., Peterson, P. M., Soreng, R. J., & Judziewicz, E. J. (2003). Catalogue of new world grasses (Poaceae): III. Subfamilies Panicoideae, Aristidoideae, Arundinoideae, and Danthonioideae (pp. 34–62).

    Google Scholar 

  17. Greenfield, J. C. (1989). Vetiver grass (Vetiveria spp.): the ideal plant for vegetative soil and moisture conservation. World Bank; Del Giudice, L., Massardo, D. R., Pontieri, P., Bertea, C. M., Mombello, D., Carata, E., ... & Alifano, P. (2008). The microbial community of vetiver root and its involvement into essential oil biogenesis. Environmental Microbiology, 10(10), 2824–2841.

    Google Scholar 

  18. Truong, P., Van, T. T., & Pinners, E. (2008). Vetiver system applications technical reference manual (pp. 89–96). The Vetiver Network International.

    Google Scholar 

  19. Plants, U. T. (2020). Useful tropical plants database. K Fern.

    Google Scholar 

  20. Joy, R. J. (2009). “SUNSHINE” VETIVERGRASS Chrysopogon zizanioides (L.) Roberty. USDA NRCS Plant Materials Center.

    Google Scholar 

  21. Grand view Research (2020) Vetiver oil market size, share & trends analysis report by application (Medical, food & beverage, spa & relaxation), by region (North America, Europe, Asia Pacific, central & South America, Middle East & Africa), and segment forecasts, 2020–2027. Grand view Research.

    Google Scholar 

  22. Paillat, L., Périchet, C., Pierrat, J. P., Lavoine, S., Filippi, J. J., Meierhenrich, U., & Fernandez, X. (2012). Purification of vetiver alcohols and esters for quantitative high-performance thin-layer chromatography determination in Haitian vetiver essential oils and vetiver acetates. Journal of Chromatography A, 1241, 103–111.

    Article  CAS  PubMed  Google Scholar 

  23. Chomchalow, N. (2001a). The utilization of vetiver as medicinal and aromatic Plants with special reference to Chomchalow N (2001b). Office of the Royal Development Projects Board.

    Google Scholar 

  24. Chomchalow, N. (2001b). The utilization of vetiver as medicinal and aromatic Plants with special reference to.Chomchalow N (2012). Office of the Royal Development Projects Board

    Google Scholar 

  25. Peyron, L. (1989). Vetiver in perfumery. La Quintessenza, 13, 4–14.

    Google Scholar 

  26. Viano, J., Gaydou, E., & Smadja, J. (1991). On the presence of intracellular bacteriums in the roots of Vetiveria zizanioides (L.). Staph Rev Cytol Biol Végét-Bot, 14, 65–70.

    Google Scholar 

  27. Putiyanan, S., Nanthachit, K., & Kittipongpatana, N. (2006). Chrysopogon zizanioides (L.) Roberty (Gramineae) part I. Pharmacognostic identification of roots. Chiang Mai University Journal (Thailand) CMU, 5(2), 179–198.

    Google Scholar 

  28. Chauhan, M. (2019). Ushira, Vetiver (Vetiveria zizanioides). Planet Ayurveda, 75(1), 12–34.

    Google Scholar 

  29. Curtis, S. (1996). Essential oils (Neal’s yard remedies). Aurier Press.

    Google Scholar 

  30. Shealy, C. N. (1998). The illustrated encyclopedia of healing remedies. Element Books Limited.

    Google Scholar 

  31. Lingga, P. (2001). Recipes of traditional medicine. PenebarSwadaya.

    Google Scholar 

  32. Usmanghani, K., Saeed, A., & Alam, M. T. (1997a). Indusyunic medicine (pp. 363–364). Faculity of Pharmacy, University of Karachi, Pakistan.

    Google Scholar 

  33. Usmanghani, K., Saeed, A., & Alam, M. T. (1997b). Indusyunic medicine: Traditional medicine of herbal animal and mineral origin in Pakistan. Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi.

    Google Scholar 

  34. Ibrahim, A. U.(1996). Uses of Vetiveria nigritana grass species inNorthern Nigeria:ACase of Bauchi State. In Abstracts of papers presented at ICV-1 (pp 1–124).

    Google Scholar 

  35. Jain, V., & Jain, S. K. (2016). Compendium of Indian folk medicine and ethnobotany (1991–2015). Deep Publications.

    Google Scholar 

  36. Singh, K. K., & Maheshwari, J. K. (1983). Traditional phytotherapy amongst the tribals of Varanasi district, Uttar Pradesh. Journal of Economic and Taxonomic Botany, 4, 829–838.

    Google Scholar 

  37. Sastry, K. N. R. (1996). Socio-economic dimensions of vetiver in rainfed areas of Karnataka (India). In Vetiver: A miracle grass (pp. 4–8).

    Google Scholar 

  38. Pripdeevech, P., Wongpornchai, S., & Promsiri, A. (2006). Highly volatile constituents of Vetiveria zizanioides roots grown under different cultivation conditions. Molecules, 11(10), 817–826.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Dowthwaite, S. V., & Rajani, S. (2000). Vetiver: Perfumer’s liquid gold. In Proceedings of ICV-2 held in Cha-am (pp. 478–81).

    Google Scholar 

  40. Lavania, U. C. (2003a). Other uses and utilization of vetiver: Vetiver oil. In The third international vetiver conference, Guangzhou (p. 475).

    Google Scholar 

  41. Bhatwadekar, S. V., Pednekar, P. R., Chakravarti, K. K., & Paknikar, S. K. (1982). Survey of sesquiterpenoids of vetiver oil. Cultivation and utilization of aromatic plants/edited by CK Atal and BM Kapur.

    Google Scholar 

  42. Demole, E. P., Holzner, G. W., & Youssefi, M. J. (1995). Malodor formation in alcoholic perfumes containing vetiveryl acetate and vetiver oil. Perfumer & Flavorist, 20(1), 35–40.

    CAS  Google Scholar 

  43. Sinha, S., Jothiramajayam, M., Ghosh, M., Jana, A., Chatterji, U., & Mukherjee, A. (2015). Vetiver oil (Java) attenuates cisplatin-induced oxidative stress, nephrotoxicity and myelosuppression in Swiss albino mice. Food and Chemical Toxicology, 81, 120–128.

    Article  CAS  PubMed  Google Scholar 

  44. Mallavarapu, G. R., Syamasundar, K. V., Ramesh, S., & Rao, B. R. R. (2012). Constituents of South Indian vetiver oils. Natural Product Communications, 7(2), 1934578X1200700228.

    Article  Google Scholar 

  45. Sellier, N., Cazaussus, A., Budzinski, H., & Lebon, M. (1991). Structure determination of sesquiterpenes in chinese vetiver oil by gas chromatography—Tandem mass spectrometry. Journal of Chromatography A, 557, 451–458.

    Article  CAS  Google Scholar 

  46. Pfau, A., & Plattner, P. (1940). Studies on volatile plant materials XI on the constituents of the β-Vetivone. Helvetica Chimica Acta, 23, 768–792.

    Article  CAS  Google Scholar 

  47. Naves, Y. R., & Perrottet, E. (1941). Volatile plant materials XIII. Alpha-and beta-vetivones. Helvetica Chimica Acta, 24, 3–29.

    Article  CAS  Google Scholar 

  48. Pinder, A. R. (1980). Further synthetic investigations in the eremophilane sesquiterpene group. Synthesis of (±)-isovalencenic acid,(±)-isovalencenol, and their (Z)-isomers, and experiments directed towards the synthesis of tessaric acid. Journal of the Chemical Society, Perkin Transactions, 1, 1752–1755.

    Article  Google Scholar 

  49. Arctander, S. (1969). Perfume and flavor chemicals:(aroma chemicals) (Vol. 2). Allured Publishing Corporation.

    Google Scholar 

  50. Umarani, D. C., Gore, K. G., & Chakravarti, K. K. (1966). Terpenoids xc: Khusimol, a new sesquiterpene alcohol. Tetrahedron Letters, 7(12), 1255–1261.

    Article  Google Scholar 

  51. Hanayama, N., Kido, F., Sakuma, R., Uda, H., & Yoshikoshi, A. (1968). Minor acidic constituents of vetiver oil. Tetrahedron Letters, 9(58), 6099–6102.

    Article  Google Scholar 

  52. Nguyen, T. A., & Feizon, M. (1965). Sesquiterpenes of vetiver oils. Am Perfum Cosmet, 80(3), 40–50.

    Google Scholar 

  53. Homma, A., Kato, M., Wu, M. D., & Yoshikoshi, A. (1970). Minor sesquiterpene alcohols of vetiver oil. Tetrahedron Letters, 11(3), 231–234.

    Article  Google Scholar 

  54. Del Giudice, L., Massardo, D. R., Pontieri, P., Bertea, C. M., Mombello, D., Carata, E., et al. (2008). The microbial community of vetiver root and its involvement into essential oil biogenesis. Environmental Microbiology, 10(10), 2824–2841.

    Article  PubMed  Google Scholar 

  55. Kaiser, R., & Naegeli, P. (1972). Biogenetically significant components in vetiver oil. Tetrahedron Letters, 13(20), 2009–2012.

    Article  Google Scholar 

  56. Weyerstahl, P., Marschall, H., Splittgerber, U., & Wolf, D. (1997). New cis-eudesm-6-ene derivatives from vetiver oil. Liebigs Annalen, 1997(8), 1783–1787.

    Article  Google Scholar 

  57. Andersen, N. H. (1970). The structures of zizanol and vetiselinenol. Tetrahedron Letters, 11(21), 1755–1758.

    Article  Google Scholar 

  58. Naegeli, P., & Kaiser, R. (1972). A new synthetic approach to the acorane-, daucane-and cedrane skeleton. Tetrahedron Letters, 13(20), 2013–2016.

    Article  Google Scholar 

  59. Paknikar, S. K., Bhatwadekar, S. V., & Chakravarti, K. K. (1975). Biogenetically significant components of vetiver oil: Occurrence of (−) X-funebrene and related compounds. Tetrahedron Letters, 16(34), 2973–2976.

    Article  Google Scholar 

  60. Zalkow, L. H., & Glower, M. G., Jr. (1975). The absolute configuration of a vetiver acoradiene. The conversion of carotol to acoradienes. Tetrahedron Letters, 16(1), 75–78.

    Article  Google Scholar 

  61. Filippi, J. J. (2014). Norsesquiterpenes as markers of overheating in Indonesian vetiver oil. Flavour and Fragrance Journal, 29(3), 137–142.

    Article  CAS  Google Scholar 

  62. Shibamoto, T., & Nishimura, O. (1982). Isolation and identification of phenols in oil of vetiver. Phytochemistry, 21(3), 793.

    Article  CAS  Google Scholar 

  63. Clery, R. A., Hammond, C. J., & Wright, A. C. (2005). Nitrogen compounds from Haitian vetiver oil. Journal of Essential Oil Research, 17(6), 591–592.

    Article  CAS  Google Scholar 

  64. Mollik, M. A. H. (2013). Combination of trichosanthes cucumerina L. compounds: An analysis for novel effects of anticancer cell activites as probes for pharmacological studies. Journal for Immunotherapy of Cancer, 1(1), 1–1.

    Google Scholar 

  65. Sharifi-Rad, M., Fokou, P. V. T., Sharopov, F., Martorell, M., Ademiluyi, A. O., Rajkovic, J., et al. (2018). Antiulcer agents: From plant extracts to phytochemicals in healing promotion. Molecules, 23(7), 1751.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Silva, N. C. C., & Fernandes Júnior, A. J. J. O. V. A. (2010). Biological properties of medicinal plants: A review of their antimicrobial activity. Journal of Venomous Animals and Toxins Including Tropical Diseases, 16, 402–413.

    Article  Google Scholar 

  67. Pareek, A. R. C. H. A. N. A., & Kumar, A. S. H. W. A. N. I. (2013). Ethnobotanical and pharmaceutical uses of Vetiveria zizanioides (Linn) Nash: a medicinal plant of Rajasthan. International Journal of Pharmacy and Life Sciences, 50, L12–L18.

    Google Scholar 

  68. Ramírez-Rueda, R. Y., Marinho, J., & Salvador, M. J. (2019). Bioguided identification of antimicrobial compounds from Chrysopogon zizaniodes (L.) Roberty root essential oil. Future Microbiology, 14(14), 1179–1189.

    Article  PubMed  Google Scholar 

  69. Hammer, K. A., Carson, C. F., & Riley, T. V. (1999). Antimicrobial activity of essential oils and other plant extracts. Journal of Applied Microbiology, 86(6), 985–990.

    Article  CAS  PubMed  Google Scholar 

  70. David, A., Wang, F., Sun, X., Li, H., Lin, J., Li, P., & Deng, G. (2019). Chemical composition, antioxidant, and antimicrobial activities of Vetiveria zizanioides (L.) Nash essential oil extracted by carbon dioxide expanded ethanol. Molecules, 24(10), 1897.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  71. Jayashree, S., Rathinamala, J., & Lakshmanaperumalsamy, P. (2011a). Antimicrobial activity of Vetiveria zizanoides against some pathogenic bacteria and fungi. Medicinal Plants-International Journal of Phytomedicines and Related Industries, 3(2), 151–156.

    Article  Google Scholar 

  72. Luqman, S., Srivastava, S., Darokar, M. P., & Khanuja, S. P. (2005). Detection of antibacterial activity in spent roots of two genotypes of aromatic grass Vetiveria zizanioides. Pharmaceutical Biology, 43(8), 732–736.

    Article  Google Scholar 

  73. Saikia, D., Parveen, S., Gupta, V. K., & Luqman, S. (2012). Anti-tuberculosis activity of Indian grass KHUS (Vetiveria zizanioides L. Nash). Complementary Therapies in Medicine, 20(6), 434–436.

    Article  PubMed  Google Scholar 

  74. Gupta, R., Sharma, K. K., Afzal, M., Damanhouri, Z. A., Ali, B., Kaur, R., et al. (2013). Anticonvulsant activity of ethanol extracts of Vetiveria zizanioides roots in experimental mice. Pharmaceutical Biology, 51(12), 1521–1524.

    Article  PubMed  Google Scholar 

  75. Luqman, S., Kumar, R., Kaushik, S., Srivastava, S., Darokar, M. P., & Khanuja, S. P. (2009). Antioxidant potential of the root of Vetiveria zizanioides (L.) Nash. Indian Journal of Biochemistry and Biophysics, 46(1), 122–125.

    CAS  PubMed  Google Scholar 

  76. Rajasekhar, C. H., Kokila, B. N., & Rakesh, R. B. (2014). Potentiating effect of vetiveria zizanioides root extract and essential oil on phenobarbital induced sedation-hypnosis in swiss albino mice. International Journal of Experimental Pharmacology, 4, 89–93.

    Google Scholar 

  77. Chou, S. T., Lai, C. P., Lin, C. C., & Shih, Y. (2012). Study of the chemical composition, antioxidant activity and anti-inflammatory activity of essential oil from Vetiveria zizanioides. Food Chemistry, 134(1), 262–268.

    Article  CAS  Google Scholar 

  78. Kim, H. J., Chen, F., Wang, X., Chung, H. Y., & Jin, Z. (2005a). Evaluation of antioxidant activity of vetiver (Vetiveria zizanioides L.) oil and identification of its antioxidant constituents. Journal of Agricultural and Food Chemistry, 53(20), 7691–7695.

    Article  CAS  PubMed  Google Scholar 

  79. Brüne, B., von Knethen, A., & Sandau, K. B. (1998). Nitric oxide and its role in apoptosis. European Journal of Pharmacology, 351(3), 261–272.

    Article  PubMed  Google Scholar 

  80. Powers, C. N., Osier, J. L., McFeeters, R. L., Brazell, C. B., Olsen, E. L., Moriarity, D. M., et al. (2018). Antifungal and cytotoxic activities of sixty commercially-available essential oils. Molecules, 23(7), 1549.

    Article  PubMed  PubMed Central  Google Scholar 

  81. Aron, P. M., & Kennedy, J. A. (2008). Flavan-3-ols: Nature, occurrence and biological activity. Molecular Nutrition & Food Research, 52(1), 79–104.

    Article  CAS  Google Scholar 

  82. Tapiero, H., Tew, K. D., Ba, G. N., & Mathe, G. (2002). Polyphenols: Do they play a role in the prevention of human pathologies? Biomedicine & Pharmacotherapy, 56(4), 200–207.

    Article  CAS  Google Scholar 

  83. Chitra, T., Jayashree, S., & Rathinamala, J. (2014). Evaluation of anticancer activity of Vetiveria zizanioides against human breast cancer. International Journal of Pharmaceutical Sciences, 6, 164–166.

    Google Scholar 

  84. Elzaawely, A. A., Xuan, T. D., & Tawata, S. (2005). Antioxidant and antibacterial activities of Rumex japonicus H OUTT. Aerial Parts. Biological and Pharmaceutical Bulletin, 28(12), 2225–2230.

    Article  CAS  PubMed  Google Scholar 

  85. Villarama, C. D., & Maibach, H. I. (2005). Glutathione as a depigmenting agent: An overview. International Journal of Cosmetic Science, 27(3), 147–153.

    Article  CAS  PubMed  Google Scholar 

  86. Tepe, B., Akpulat, H. A., & Sokmen, M. (2011). Evaluation of the chemical composition and antioxidant activity of the essential oils of Peucedanum longifolium (Waldst. & Kit.) and P. palimbioides (Boiss.). Records of Natural Products, 5(2), 108.

    CAS  Google Scholar 

  87. Tarai, D. K., Nayak, S., & Karan, S. (2010). In vitro free radical scavenging activity of Vetiveria zizanioides. Journal of Pharmacy Research, 3(4), 681–683.

    Google Scholar 

  88. Al-Kharusi, N., Babiker, H. A., Al-Salam, S., Waly, M. I., Nemmar, A., Al-Lawati, I., et al. (2013). Ellagic acid protects against cisplatin-induced nephrotoxicity in rats: a dose-dependent study. European Review for Medical and Pharmacological Sciences, 17(3), 299–310.

    CAS  PubMed  Google Scholar 

  89. Chirino, Y. I., & Pedraza-Chaverri, J. (2009). Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity. Experimental and Toxicologic Pathology, 61(3), 223–242.

    Article  CAS  PubMed  Google Scholar 

  90. An, Y., Xin, H., Yan, W., & Zhou, X. (2011). Amelioration of cisplatin-induced nephrotoxicity by pravastatin in mice. Experimental and Toxicologic Pathology, 63(3), 215–219.

    Article  CAS  PubMed  Google Scholar 

  91. Rao, R. C., Gal, C. S. L., Granger, I., Gleye, J., Augereau, J. M., & Bessibes, C. (1994). Khusimol, a non-peptide ligand for vasopressin V1a receptors. Journal of Natural Products, 57(10), 1329–1335.

    Article  CAS  PubMed  Google Scholar 

  92. Thubthimthed, S., Thisayakorn, K., Rerk-am, U., Tangstirapakdee, S., & Suntorntanasat, T. (2003, October). Vetiver oil and its sedative effect. In The 3rd international vetiver conference, Guangzhou (492–494).

    Google Scholar 

  93. Dikshit, A. (1984). Antifungal action of some essential oils against animal pathogens. Fitoterapia, 55, 171–176.

    CAS  Google Scholar 

  94. Kaushal, S., & Chahal, K. K. (2008). Schiff bases of khusilal: Synthesis and their antifungal activity. Pestology, 32, 47–49.

    CAS  Google Scholar 

  95. Sharma, P. K., Raina, A. P., & Dureja, P. (2009). Evaluation of the antifungal and phytotoxic effects of various essential oils against Sclerotium rolfsii (Sacc) and Rhizoctonia bataticola (Taub). Archives of Phytopathology and Plant Protection, 42(1), 65–72.

    Article  CAS  Google Scholar 

  96. Dubey, N., Raghav, C. S., Gupta, R. L., & Chhonkar, S. S. (2010a). Chemical composition and antifungal activity of vetiver oil of North and South India against Rhizoctonia solani. Pesticide Research Journal, 22, 63–67.

    CAS  Google Scholar 

  97. Sangeetha, D., & Stella, D. (2012). Screening of antimicrobial activity of vetiver extracts against certain pathogenic microorganisms. International Journal of Pharmacy and Biological Sciences, 3(1), 197–203.

    Google Scholar 

  98. Jain, S. C., Nowicki, S., Eisner, T., & Meinwald, J. (1982). Insect repellents from vetiver oil: I. Zizanal and epizizanal. Tetrahedron Letters, 23(45), 4639–4642.

    Article  CAS  Google Scholar 

  99. Karintanyakit, P., & Babpraserth, C. (1996). Vegetables pest management by using essential oil from vetiver grass (Vetiveria zizanioides Nash). In Vetiver: A Miracle Grass, Chiang Rai (Thailand) (pp. 4–8).

    Google Scholar 

  100. Ndemah, R., Gounou, S., & Schulthess, F. (2002). The role of wild grasses in the management of lepidopterous stem-borers on maize in the humid tropics of western Africa. Bulletin of Entomological Research, 92(6), 507–519.

    Article  CAS  PubMed  Google Scholar 

  101. Chomchalow, N., Lekskul, S., Pichitakul, N., & Wasuwat, S. (1970). Researches on essential oils at ASRCT. ASST Newsletters, 3(5–6), 49–63.

    Google Scholar 

  102. Zhu, B. C., Henderson, G., Chen, F., Maistrello, L., & Laine, R. A. (2001). Nootkatone is a repellent for Formosan subterranean termite (Coptotermes formosanus). Journal of Chemical Ecology, 27(3), 523–531.

    Article  CAS  PubMed  Google Scholar 

  103. Nix, K. E., Henderson, G., & Laine, R. A. (2003). Field evaluation of nootkatone and tetrahydronootkatone as wood treatments against Coptotermes formosanus. Sociobiology, 42(2), 413.

    Google Scholar 

  104. Maistrello, L., Henderson, G., & Laine, R. A. (2001). Efficacy of vetiver oil and nootkatone as soil barriers against Formosan subterranean termite (Isoptera: Rhinotermitidae). Journal of Economic Entomology, 94(6), 1532–1537.

    Article  CAS  PubMed  Google Scholar 

  105. Maistrello, L., Henderson, G., & Laine, R. A. (2003). Comparative effects of vetiver oil, nootkatone and disodium octaborate tetrahydrate on Coptotermes formosanus and its symbiotic fauna. Pest Management Science: Formerly Pesticide Science, 59(1), 58–68.

    Article  CAS  Google Scholar 

  106. Ibrahim, S. A., Henderson, G., Zhu, B. C., Fei, H., & Laine, R. A. (2004). Toxicity and behavioral effects of nootkatone, 1, 10-dihydronootkatone, and tetrahydronootkatone to the formosan subterranean termite (Isoptera: Rhinotermitidae). Journal of Economic Entomology, 97(1), 102–111.

    Article  CAS  PubMed  Google Scholar 

  107. Sujatha, S. (2010). Essential oil and its insecticidal activity of medicinal aromatic plant Vetiveria zizanioides (L.) against the red flour beetle Tribolium castaneum (Herbst). Asian Journal of Agricultural Sciences, 2(3), 84–88.

    Google Scholar 

  108. Pangnakorn, U. (2009). Efficiency of vetiver grass extracts against Cowpea Weevil (Callosobruchus maculatus Fabr.). American-Eurasian Journal of Agricultural & Environmental Sciences, 6, 356–359.

    Google Scholar 

  109. Aarthi, N., & Murugan, K. (2010). Larvicidal and repellent activity of Vetiveria zizanioides L, Ocimum basilicum Linn and the microbial pesticide spinosad against malarial vector, Anopheles stephensi Liston (Insecta: Diptera: Culicidae). Journal of Biopesticides, 3(1), 199–204.

    Google Scholar 

  110. Vimala, Y., Anuj, K. A., & Gupta, M. K. (2005). Physico-chemical interpretation of allelopathic interaction of vetiver with two non-edible oil yielding fence plants. Journal of Experimental Botany, 2, 141–150.

    Google Scholar 

  111. Bernauer, U., Bodin, L., Chaudhry, Q., Coenraads, P., Dusinska, M., Ezendam, J., et al. (2019). Opinion of the scientific committee on consumer safety (SCCS)–final opinion on the safety of fragrance ingredient acetylated vetiver oil (AVO)-(Vetiveria zizanioides root extract acetylated)-submission III. Regulatory Toxicology and Pharmacology, 107, 104389.

    Article  Google Scholar 

  112. Bilici, M., Efe, H., Köroğlu, M. A., Uydu, H. A., Bekaroğlu, M., & Değer, O. (2001). Antioxidative enzyme activities and lipid peroxidation in major depression: Alterations by antidepressant treatments. Journal of Affective Disorders, 64(1), 43–51.

    Article  CAS  PubMed  Google Scholar 

  113. Karan, S. K., Pal, D., Mishra, S. K., & Mondal, A. (2013). Antihyperglycaemic effect of Vetiveria zizanioides (L.) Nash root extract in alloxan induced diabetic rats. Asian Journal of Chemistry, 25(3), 1555.

    CAS  Google Scholar 

  114. Ben-Shaul, V., Lomnitski, L., Nyska, A., Zurovsky, Y., Bergman, M., & Grossman, S. (2001). The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge. Toxicology Letters, 123(1), 1–10.

    Article  CAS  PubMed  Google Scholar 

  115. Xin, C., Xiaojing, L., Jiao, W., Haofu, D., & Wenquan, W. (2010). Study on chemical composition and antifungal activity in volatile oil of Alpinia oxyphylla Miq fruits. Chinese Agricultural Science Bulletin, 26, 366–371.

    Google Scholar 

  116. Munoz-Munoz, J. L., García-Molina, F., Varón, R., Tudela, J., García-Cánovas, F., & Rodríguez-López, J. N. (2009). Generation of hydrogen peroxide in the melanin biosynthesis pathway. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 1794(7), 1017–1029.

    Article  CAS  PubMed  Google Scholar 

  117. Liu, G. S., Peshavariya, H., Higuchi, M., Brewer, A. C., Chang, C. W., Chan, E. C., & Dusting, G. J. (2012). Microphthalmia-associated transcription factor modulates expression of NADPH oxidase type 4: a negative regulator of melanogenesis. Free Radical Biology and Medicine, 52(9), 1835–1843.

    Article  CAS  PubMed  Google Scholar 

  118. Panich, U., Tangsupa-a-nan, V., Onkoksoong, T., Kongtaphan, K., Kasetsinsombat, K., Akarasereenont, P., & Wongkajornsilp, A. (2011). Inhibition of UVA-mediated melanogenesis by ascorbic acid through modulation of antioxidant defense and nitric oxide system. Archives of Pharmacal Research, 34(5), 811–820.

    Article  CAS  PubMed  Google Scholar 

  119. Khater, H. F. (2012). Prospects of botanical biopesticides in insect pest management. Pharmacologia, 3(12), 641–656.

    Article  Google Scholar 

  120. Khater, H. F., & Geden, C. J. (2018). Potential of essential oils to prevent fly strike and their effects on the longevity of adult Lucilia sericata. Journal of Vector Ecology, 43(2), 261–270.

    Article  PubMed  Google Scholar 

  121. Khater, H. F., & Geden, C. J. (2019). Efficacy and repellency of some essential oils and their blends against larval and adult house flies, Musca domestica L.(Diptera: Muscidae). Journal of Vector Ecology, 44(2), 256–263.

    Article  PubMed  Google Scholar 

  122. Murugan, K., Priyanka, V., Dinesh, D., Madhiyazhagan, P., Panneerselvam, C., Subramaniam, J., et al. (2015). Predation by Asian bullfrog tadpoles, Hoplobatrachus tigerinus, against the dengue vector, Aedes aegypti, in an aquatic environment treated with mosquitocidal nanoparticles. Parasitology Research, 114(10), 3601–3610.

    Article  PubMed  Google Scholar 

  123. Roni, M., Murugan, K., Panneerselvam, C., Subramaniam, J., Nicoletti, M., Madhiyazhagan, P., et al. (2015). Characterization and biotoxicity of Hypnea musciformis-synthesized silver nanoparticles as potential eco-friendly control tool against Aedes aegypti and Plutella xylostella. Ecotoxicology and Environmental Safety, 121, 31–38.

    Article  CAS  PubMed  Google Scholar 

  124. Saiyudthong, S., Pongmayteegul, S., Marsden, C. A., & Phansuwan-Pujito, P. (2015). Anxiety-like behaviour and c-fos expression in rats that inhaled vetiver essential oil. Natural Product Research, 29(22), 2141–2144.

    Article  CAS  PubMed  Google Scholar 

  125. Cheaha, D., Issuriya, A., Manor, R., Kwangjai, J., Rujiralai, T., & Kumarnsit, E. (2016). Modification of sleep-waking and electroencephalogram induced by vetiver essential oil inhalation. Journal of Intercultural Ethnopharmacology, 5(1), 72.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  126. Nirwane, A. M., Gupta, P. V., Shet, J. H., & Patil, S. B. (2015). Anxiolytic and nootropic activity of Vetiveria zizanioides roots in mice. Journal of Ayurveda and Integrative Medicine, 6(3), 158.

    Article  PubMed  PubMed Central  Google Scholar 

  127. Velmurugan, C., Shajahan, S. K., Kumar, A., Kumar, V., & Thomas, S. (2014). Memory and learning enhancing activity of different extracts of roots of Vetiveria zizanioides. International Journal of Novel Trends in Pharmaceutical Sciences, 4(6), 174–182.

    Google Scholar 

  128. Bizzo, H. R., Hovell, A. M. C., & de Rezende, C. M. (2009). Essential oils in Brazil: General aspects, production and perspective. Quim Nova, 32(3), 588–594.

    Article  CAS  Google Scholar 

  129. Facey, P. C., Porter, R. B., Reese, P. B., & Williams, L. A. (2005). Biological activity and chemical composition of the essential oil from Jamaican Hyptis verticillata Jacq. Journal of Agricultural and Food Chemistry, 53(12), 4774–4777.

    Article  CAS  PubMed  Google Scholar 

  130. Williams, L. A. (1993). Adverse effects of extracts of artocarpus altilis park, and azadirachta indica (A. juss) on the reproductive physiology of the adult female tick, boophilus microplus (canest.). Invertebrate Reproduction & Development, 23(2–3), 159–164.

    Article  Google Scholar 

  131. WILLIAMS, L. A., GARDNER, M. T., SINGH, P. D., THE, T. L., FLETCHER, C. K., CALED-WILLIAMS, L. I. S. A., & KRAUS, W. (1997). Mode of action studies of the acaricidal agent, epingaione. Invertebrate Reproduction & Development, 31(1–3), 231–236.

    Article  CAS  Google Scholar 

  132. Loizzo, M. R., Tundis, R., Conforti, F., Menichini, F., Bonesi, M., Nadjafi, F., et al. (2010). Salvia leriifolia Benth (Lamiaceae) extract demonstrates in vitro antioxidant properties and cholinesterase inhibitory activity. Nutrition Research, 30(12), 823–830.

    Article  CAS  PubMed  Google Scholar 

  133. Ribeiro, V. L. S., Vanzella, C., dos Santos Moysés, F., Dos Santos, J. C., Martins, J. R. S., von Poser, G. L., & Siqueira, I. R. (2012). Effect of Calea serrata less. N-hexane extract on acetylcholinesterase of larvae ticks and brain Wistar rats. Veterinary Parasitology, 189(2–4), 322–326.

    Article  PubMed  Google Scholar 

  134. Ribeiro, V. L. S., Avancini, C., Gonçalves, K., Toigo, E., & von Poser, G. (2008). Acaricidal activity of Calea serrata (Asteraceae) on Boophilus microplus and Rhipicephalus sanguineus. Veterinary Parasitology, 151(2–4), 351–354.

    Article  PubMed  Google Scholar 

  135. Clemente, M. A., de Oliveira Monteiro, C. M., Scoralik, M. G., Gomes, F. T., de Azevedo Prata, M. C., & Daemon, E. (2010). Acaricidal activity of the essential oils from Eucalyptus citriodora and Cymbopogon nardus on larvae of Amblyomma cajennense (Acari: Ixodidae) and Anocentor nitens (Acari: Ixodidae). Parasitology Research, 107(4), 987–992.

    Article  PubMed  Google Scholar 

  136. Arrigoni-Blank, M. D. F., Santos, A. V., & Blank, A. F. (2011). Direct organogenesis and acclimatization of patchouli. Horticultura Brasileira, 29, 145–150.

    Article  Google Scholar 

  137. Barros, G. C., Tresvenzol, L. M., Cunha, L. C., Ferri, P. H., Paula, J. R., & Bara, M. T. F. (2009). Composição química, atividade antibacteriana e avaliação da toxicidade aguda de Vetiveria zizanoides L. Nash (Poaceae). Latin American Journal of Pharmacy, 28, 531–537.

    CAS  Google Scholar 

  138. Rattan, R. S. (2010). Mechanism of action of insecticidal secondary metabolites of plant origin. Crop Protection, 29(9), 913–920.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sadia Zafar .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Zafar, S., Khan, I.M., Muddasar, M., Iqbal, R., Gohar, U.F. (2023). Khus. In: Zia-Ul-Haq, M., Abdulkreem AL-Huqail, A., Riaz, M., Farooq Gohar, U. (eds) Essentials of Medicinal and Aromatic Crops. Springer, Cham. https://doi.org/10.1007/978-3-031-35403-8_26

Download citation

Publish with us

Policies and ethics