Abstract
Repeat two-stage revision for knee periprosthetic joint infection (PJI) is an effective method of treatment. However, there is a higher prevalence of failure in those subjects with poor general health based on the MSIS (Musculoskeletal Infection Society score), inadequate soft tissue envelope, and resistant bacteria. Seventy-eight percent of subjects experience reimplantation after a repeat implant removal. Of those who complete the second-stage surgery, 37% experience additional revision for infection and 14% experience amputation. The reinfection-free implant survivorship amounts to 77% after 1 year and 38% after 5 years. Knee arthrodesis should be strongly considered as the treatment of choice for subjects who have persistent infected total knee arthroplasty (TKA) after a failed two-stage reimplantation procedure.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Wu CH, Gray CF, Lee GC. Arthrodesis should be strongly considered after failed two-stage reimplantation TKA. Clin Orthop Relat Res. 2014;472:3295–304.
Fehring KA, Abdel MP, Ollivier M, Mabry TM, Hanssen AD. Repeat two-stage exchange arthroplasty for periprosthetic knee infection is dependent on host grade. J Bone Joint Surg Am. 2017;99:19–24.
McPherson EJ, Tontz W Jr, Patzakis M, Woodsome C, Holton P, Norris L, et al. Outcome of infected total knee utilizing a staging system for prosthetic joint infection. Am J Orthop (Belle Mead NJ). 1999;28:161–5.
Vadiee I, Backstein DJ. The effectiveness of repeat two-stage revision for the treatment of recalcitrant total knee arthroplasty infection. J Arthroplast. 2019;34:369–74.
Maden C, Jaibaji M, Konan S, Zagra L, Borella M, Harvey A, et al. The outcomes of surgical management of failed two-stage revision knee arthroplasty. Acta Biomed. 2021;92(3):e2021197.
Steinicke AC, Schwarze J, Gosheger G, Moellenbeck B, Ackmann T, Theil C. Repeat two-stage exchange arthroplasty for recurrent periprosthetic hip or knee infection: what are the chances for success? Arch Orthop Trauma Surg. 2022; https://doi.org/10.1007/s00402-021-04330-z. Online ahead of print.
Neufeld ME, Liechti EF, Soto F, Linke P, Busch SM, Gehrke T, et al. High revision rates following repeat septic revision after failed one-stage exchange for periprosthetic joint infection in total knee arthroplasty. Bone Joint J. 2022;104-B:386–93.
Christiner T, Yates P, Prosser G. Repeat two-stage revision for knee prosthetic joint infection results in very high failure rates. ANZ J Surg. 2022;92:487–92.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Rodríguez-Merchán, E.C. (2023). Repeat Two-Stage Revision for Knee Periprosthetic Joint Infection. In: Rodríguez-Merchán, E.C. (eds) Advances in Orthopedic Surgery of the Knee. Springer, Cham. https://doi.org/10.1007/978-3-031-33061-2_15
Download citation
DOI: https://doi.org/10.1007/978-3-031-33061-2_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-33060-5
Online ISBN: 978-3-031-33061-2
eBook Packages: MedicineMedicine (R0)